TY  - JOUR
TI  - Perinatal and Medical Risk Factors in Children with Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder or Specific Learning Disorder: Comparison Between Diagnostic Groups
AB  - Introduction: Epigenetic changes in the pathogenesis ofneurodevelopmental disorders, including prenatal and earlylife exposures, are becoming as appealing as hereditarygenes. This study aimed to investigate possible pre-pubertalenvironmental and developmental risk factors for childrenwith Attention Deficit Hyperactivity Disorder (ADHD), AutismSpectrum Disorder (ASD), and Specific Learning Disorder (SLD).Methods: The study included 98 children (24 ADHD, 24 SLD,26 ASD, 20 controls) aged 7-12 years. The diagnostic evaluationwas based on the American Psychiatric Association Diagnosticand Statistical Manual of Mental Disorders and Schedule forAffective Disorders and Schizophrenia for School-age Childrenpresentversion. Parents completed socio-demographic dataform for clinical evaluation, and The Wechsler Children’sIntelligence scale was used to assess cognitive skills.Results: In our study, low parental education level, parentalunemployment, low-income, and history of psychiatricdisorders in first-degree relatives were associated with SLDrisk, prematurity, and early self-regulation difficulties wereassociated with ASD risk, and history of allergy was associatedwith ADHD risk.Conclusion: In this study, the presence of many differentrisk factors that play a possible role in neurodevelopmentaldisorders suggests that further epigenetic studies are needed.
AU  - Karabekiroglu, Koray
AU  - Bozkurt, abdullah
AU  - Şahin, Berkan
DO  - 10.4274/imj.galenos.2019.02347
PY  - 2019
JO  - İstanbul Medical Journal
VL  - 20
IS  - 6
SN  - 2619-9793
SP  - 502
EP  - 507
DB  - TRDizin
UR  - http://search/yayin/detay/333282
ER  -