Yıl: 2019 Cilt: 3 Sayı: 2 Sayfa Aralığı: 112 - 115 Metin Dili: İngilizce DOI: 10.14744/ejmo.2019.31913

Does Vitamin D Replacement Alter the Chemotherapy Outcome in Lung Cancer

Öz:
Objectives: Lung cancer accounts for 20% of cancer-related deaths worldwide. Several studies have shown that Vitamin D levels at the time of diagnosis are prognostic in lung cancer. In this study, we evaluated the relationship betweenpre-diagnosis Vitamin D replacement levels and platinum-based chemotherapy results.Methods: In this cross-sectional study, we retrospectively analyzed archive records of all 247 patients diagnosed withlung cancer from an oncology center in Turkey, between 2012-2018. The chemotherapy outcomes, Vitamin D levels andreplacement doses of these patients up to 6 months ago were recorded.Results: Vitamin D levels of 153 patients were below 15 ng/mL, 65 patients had a level of 15-30 ng/mL, and 29 patientshad a vitamin D level higher than 30 ng/mL. In the study population, 215 had a replacement below 300.000 IU whereas32 had a replacement above 300.000 IU. When the patients were evaluated based on their chemotherapy responses, nodifference was observed between the patients with below and above 300.000 IU. In our study, Vitamin D and replacement level at the time of diagnosis did not change the chemotherapy response.Conclusion: Vitamin D replacement levels were not significantly associated with chemotherapy outcomes in our study.
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APA ARAZ M, BEYPINAR İ, BEYPINAR D, DEMİR H, UYSAL M (2019). Does Vitamin D Replacement Alter the Chemotherapy Outcome in Lung Cancer. Eurasian Journal of Medicine and Oncology, 3(2), 112 - 115. 10.14744/ejmo.2019.31913
Chicago ARAZ MURAT,BEYPINAR İsmail,BEYPINAR Dilek,DEMİR Hacer,UYSAL Mükremin Does Vitamin D Replacement Alter the Chemotherapy Outcome in Lung Cancer. Eurasian Journal of Medicine and Oncology 3, no.2 (2019): 112 - 115. 10.14744/ejmo.2019.31913
MLA ARAZ MURAT,BEYPINAR İsmail,BEYPINAR Dilek,DEMİR Hacer,UYSAL Mükremin Does Vitamin D Replacement Alter the Chemotherapy Outcome in Lung Cancer. Eurasian Journal of Medicine and Oncology, vol.3, no.2, 2019, ss.112 - 115. 10.14744/ejmo.2019.31913
AMA ARAZ M,BEYPINAR İ,BEYPINAR D,DEMİR H,UYSAL M Does Vitamin D Replacement Alter the Chemotherapy Outcome in Lung Cancer. Eurasian Journal of Medicine and Oncology. 2019; 3(2): 112 - 115. 10.14744/ejmo.2019.31913
Vancouver ARAZ M,BEYPINAR İ,BEYPINAR D,DEMİR H,UYSAL M Does Vitamin D Replacement Alter the Chemotherapy Outcome in Lung Cancer. Eurasian Journal of Medicine and Oncology. 2019; 3(2): 112 - 115. 10.14744/ejmo.2019.31913
IEEE ARAZ M,BEYPINAR İ,BEYPINAR D,DEMİR H,UYSAL M "Does Vitamin D Replacement Alter the Chemotherapy Outcome in Lung Cancer." Eurasian Journal of Medicine and Oncology, 3, ss.112 - 115, 2019. 10.14744/ejmo.2019.31913
ISNAD ARAZ, MURAT vd. "Does Vitamin D Replacement Alter the Chemotherapy Outcome in Lung Cancer". Eurasian Journal of Medicine and Oncology 3/2 (2019), 112-115. https://doi.org/10.14744/ejmo.2019.31913