TY  - JOUR
TI  - Does Vitamin D Replacement Alter the Chemotherapy Outcome in Lung Cancer
AB  - Objectives: Lung cancer accounts for 20% of cancer-related deaths worldwide. Several studies have shown that Vitamin D levels at the time of diagnosis are prognostic in lung cancer. In this study, we evaluated the relationship betweenpre-diagnosis Vitamin D replacement levels and platinum-based chemotherapy results.Methods: In this cross-sectional study, we retrospectively analyzed archive records of all 247 patients diagnosed withlung cancer from an oncology center in Turkey, between 2012-2018. The chemotherapy outcomes, Vitamin D levels andreplacement doses of these patients up to 6 months ago were recorded.Results: Vitamin D levels of 153 patients were below 15 ng/mL, 65 patients had a level of 15-30 ng/mL, and 29 patientshad a vitamin D level higher than 30 ng/mL. In the study population, 215 had a replacement below 300.000 IU whereas32 had a replacement above 300.000 IU. When the patients were evaluated based on their chemotherapy responses, nodifference was observed between the patients with below and above 300.000 IU. In our study, Vitamin D and replacement level at the time of diagnosis did not change the chemotherapy response.Conclusion: Vitamin D replacement levels were not significantly associated with chemotherapy outcomes in our study.
AU  - Beypinar, Ismail
AU  - demir, hacer
AU  - Uysal, Mukremin
AU  - araz, murat
AU  - Beypınar, Dilek
DO  - 10.14744/ejmo.2019.31913
PY  - 2019
JO  - Eurasian Journal of Medicine and Oncology
VL  - 3
IS  - 2
SN  - 2587-2400
SP  - 112
EP  - 115
DB  - TRDizin
UR  - http://search/yayin/detay/333570
ER  -