TY  - JOUR
TI  - The Safety and Efficacy of Propofol Combinations with Ketamine or Fentanyl in Lumbar Puncture Application in Children with Haematological Diseases: A Prospective, Randomised, Single-Blinded Study
AB  - Objectives: The aim of the study was to evaluate reliability, efficiency and side effects of two different combinationsthat are ketamine-propofol and fentanyl-propofol, in pediatric hematology patients undergoing lumbar puncture (LP).Methods: A total of 100 paediatric cases, aged 4-14 years, who were planned to undergo LP procedure were administered two different sedo-analgesia protocols. An anesthetist administered ketamine 1 mg/kg intravascularly (iv) to theketamine group (K), then after 1 min 2 mg/kg propofol was administered iv. In the fentanyl group (F), 1 mcg/kg fentanylwas given and after 1 min 2 mg/kg propofol was administered iv. All patients were monitorized and the heart rate,blood pressure, oxygen saturation, number of LP attempts, the side effects and also additional doses and the physiciansatisfaction were recorded.Results: The requirement for additional doses was higher in Group F (p<0.001) and the physician satisfaction was lowerin Group F (p=0.021). When hemodynamic parameters were compared, the reduction in F group was determined asgreater than that in K group (p<0.01).Conclusion: Safe and effective sedation has been obtained with both protocols during LP. However, the ketaminepropofol combination had a lower requirement for additional doses and the physician satisfaction level was higher.
AU  - Sever, Feyza
AU  - ANDIRAN ŞENAYLI, Yeşim
AU  - keskin, gülşen
AU  - KURT, Devrim Tanıl
AU  - Ozmert, Sengul
AU  - YARALI, NESE
AU  - Saydam, Sibel
AU  - Akin, Mine
AU  - Kirkiz, Serap
DO  - 10.14744/ejmo.2019.70524
PY  - 2019
JO  - Eurasian Journal of Medicine and Oncology
VL  - 3
IS  - 2
SN  - 2587-2400
SP  - 120
EP  - 125
DB  - TRDizin
UR  - http://search/yayin/detay/333581
ER  -