TY  - JOUR
TI  - Multicenter study of levodopa carbidopa intestinal gel in Parkinson’s disease: the Turkish experience
AB  - Background/aim: Our purpose was to determine the efficacy of levodopa carbidopa intestinal gel (LCIG) in a series of Turkish patientswith Parkinson’s disease (PD).Materials and methods: We had telephone calls with 54 patients from 11 neurology centers who were on LCIG treatment, and 44patients or their caregivers were included in an eight-item survey between September 2015 and June 2016. The reliability and validity ofthe survey were evaluated with intraclass correlation coefficients for every question separately.Results: Average age of the patients were 63.48 and the duration of PD was 12.79 years. Average LCIG treatment period was 15.63months. Percentages of the patients who reported they were ‘better’ after LCIG treatment were as follows: 80% for time spent off, 55% fordyskinesia, 65% for tremor, 85% for gait disorder, 50% for pain, 50% for sleep disorders, 42.5% for depression, 32.5% for incontinence,and 70% for activities of daily living. Cronbach’s alpha was 0.795 and the intraclass correlation coefficient was reliable for the items.Conclusion: As detected by a survey performed by telephone calls with good interrater reliability, patients with PD improve with LCIGtreatment in many aspects of the disease.
AU  - TEZCAN, Sabiha
AU  - Ulukan, Çağrı
AU  - Kenangil, Gulay
AU  - BORA TOKCAER, Ayse
AU  - HANAĞASI, HAŞMET AYHAN
AU  - ÇAKMUR, Raif
AU  - Elibol, Bulent
AU  - GÜLTEKİN, Murat
AU  - BİLGİÇ, BAŞAR
AU  - GÜNAL, DILEK
AU  - AKBOSTANCI, Muhittin Cenk
AU  - MİRZA, Meral
AU  - DOGU, OKAN
AU  - ERER ÖZBEK, Çiğdem Sevda
AU  - KUSBECI, Ozge Yilmaz
DO  - 10.3906/sag-1904-150
PY  - 2020
JO  - Turkish Journal of Medical Sciences
VL  - 50
IS  - 1
SN  - 1300-0144
SP  - 66
EP  - 85
DB  - TRDizin
UR  - http://search/yayin/detay/334237
ER  -