Yıl: 2019 Cilt: 35 Sayı: 3 Sayfa Aralığı: 185 - 192 Metin Dili: İngilizce DOI: 10.5146/tjpath.2018.01453 İndeks Tarihi: 06-05-2020

Gleason Score Correlation Between Prostate Needle Biopsy and Radical Prostatectomy Materials

Öz:
Objective: Prostate cancer is the second most common cancer in men. Digital rectal examination, transrectal ultrasonography and serum prostatespecific antigen represents a diagnostic triad for the detection of prostatic carcinoma. About 50 years ago, Dr. Donald Gleason created a gradingsystem for prostate cancer based on its histologic patterns. Currently, this system maintains its validity with various changes. New updates weremade in 2005 and 2014 by the International Society of Urological Pathology. The goal of biopsies is to determine the Gleason score and prognosisin prostatectomy material. The aim of this study was to determine the concordance of the Gleason score, tumor volume and tumor lateralitybetween prostate needle biopsy and prostatectomy materials.Material and Method: The study was performed with 112 patients who had biopsy and prostatectomy materials. The Gleason grades of thetumors have been evaluated with the new grading system. Tumor volumes were calculated by the number of positive blocks while tumor lateralitywas evaluated as unilateral or bilateral. Statistical analysis was performed on the obtained data.Results: Gleason score, tumor volume and tumor laterality discordance between needle biopsy and prostatectomy materials was found to bestatistically significant. However, the concordance increased as the Gleason score and tumor volume increased.Conclusion: Digital examination, serum prostate specific antigen value and needle biopsy together are very sensitive for a prostate adenocarcinomadiagnosis. The Gleason score, localization and volume of the tumors are important for patient follow-up, treatment and prognosis.
Anahtar Kelime:

Konular: Patoloji Cerrahi
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA YELDİR N, YILDIZ E, DÜNDAR G (2019). Gleason Score Correlation Between Prostate Needle Biopsy and Radical Prostatectomy Materials. , 185 - 192. 10.5146/tjpath.2018.01453
Chicago YELDİR Neşe,YILDIZ Esin,DÜNDAR Gökçe Gleason Score Correlation Between Prostate Needle Biopsy and Radical Prostatectomy Materials. (2019): 185 - 192. 10.5146/tjpath.2018.01453
MLA YELDİR Neşe,YILDIZ Esin,DÜNDAR Gökçe Gleason Score Correlation Between Prostate Needle Biopsy and Radical Prostatectomy Materials. , 2019, ss.185 - 192. 10.5146/tjpath.2018.01453
AMA YELDİR N,YILDIZ E,DÜNDAR G Gleason Score Correlation Between Prostate Needle Biopsy and Radical Prostatectomy Materials. . 2019; 185 - 192. 10.5146/tjpath.2018.01453
Vancouver YELDİR N,YILDIZ E,DÜNDAR G Gleason Score Correlation Between Prostate Needle Biopsy and Radical Prostatectomy Materials. . 2019; 185 - 192. 10.5146/tjpath.2018.01453
IEEE YELDİR N,YILDIZ E,DÜNDAR G "Gleason Score Correlation Between Prostate Needle Biopsy and Radical Prostatectomy Materials." , ss.185 - 192, 2019. 10.5146/tjpath.2018.01453
ISNAD YELDİR, Neşe vd. "Gleason Score Correlation Between Prostate Needle Biopsy and Radical Prostatectomy Materials". (2019), 185-192. https://doi.org/10.5146/tjpath.2018.01453
APA YELDİR N, YILDIZ E, DÜNDAR G (2019). Gleason Score Correlation Between Prostate Needle Biopsy and Radical Prostatectomy Materials. Türk Patoloji Dergisi, 35(3), 185 - 192. 10.5146/tjpath.2018.01453
Chicago YELDİR Neşe,YILDIZ Esin,DÜNDAR Gökçe Gleason Score Correlation Between Prostate Needle Biopsy and Radical Prostatectomy Materials. Türk Patoloji Dergisi 35, no.3 (2019): 185 - 192. 10.5146/tjpath.2018.01453
MLA YELDİR Neşe,YILDIZ Esin,DÜNDAR Gökçe Gleason Score Correlation Between Prostate Needle Biopsy and Radical Prostatectomy Materials. Türk Patoloji Dergisi, vol.35, no.3, 2019, ss.185 - 192. 10.5146/tjpath.2018.01453
AMA YELDİR N,YILDIZ E,DÜNDAR G Gleason Score Correlation Between Prostate Needle Biopsy and Radical Prostatectomy Materials. Türk Patoloji Dergisi. 2019; 35(3): 185 - 192. 10.5146/tjpath.2018.01453
Vancouver YELDİR N,YILDIZ E,DÜNDAR G Gleason Score Correlation Between Prostate Needle Biopsy and Radical Prostatectomy Materials. Türk Patoloji Dergisi. 2019; 35(3): 185 - 192. 10.5146/tjpath.2018.01453
IEEE YELDİR N,YILDIZ E,DÜNDAR G "Gleason Score Correlation Between Prostate Needle Biopsy and Radical Prostatectomy Materials." Türk Patoloji Dergisi, 35, ss.185 - 192, 2019. 10.5146/tjpath.2018.01453
ISNAD YELDİR, Neşe vd. "Gleason Score Correlation Between Prostate Needle Biopsy and Radical Prostatectomy Materials". Türk Patoloji Dergisi 35/3 (2019), 185-192. https://doi.org/10.5146/tjpath.2018.01453