Yıl: 2019 Cilt: 49 Sayı: 1 Sayfa Aralığı: 222 - 229 Metin Dili: İngilizce DOI: 10.3906/sag-1807-295 İndeks Tarihi: 08-05-2020

Polypharmacy and drug-related problems among people living with HIV/AIDS: a singlecenter experience

Öz:
Background/aim: The HIV-infected population is aging, and the concomitant comorbidities increase the likelihood of polypharmacy.There is a scarcity of data for determining drug-related problems in people living with HIV/AIDS (PLWHA).Materials and methods: This cross-sectional study was carried out between 1 September 2015 and 1 July 2016. All patients underwenta face-to-face interview with a clinical pharmacist. PCNE Classification V 7.0 was used classify incident drug-related problems (DRPs).Results: The mean age of the patients was 40.4 ± 13.06 years. The rate of polypharmacy was 66.1% in patients with comorbidities and12.3% in those without comorbidities (P < 0.001). DRPs were more prominent in older patients (46 vs. 37 years, P < 0.001), those withlonger durations of antiretroviral therapy (ART) (45 vs. 27 months, P = 0.014), and those with lower education levels (P = 0.013).Receiving >3 ART drugs was associated with more DRPs in the logistic regression model (odds ratio: 8.299, 95% confidence interval:1.924–35.803). Fifty-eight interventions were performed in 45 (24.9%) patients. Clinical pharmacist interventions were performed in18.9% of patients without polypharmacy and in 38.9% of patients with polypharmacy (P < 0.001).Conclusion: DRPs and polypharmacy are common among elderly PLWHA. More interventions are warranted to boost the quality oflife in aging PLWHA.
Anahtar Kelime:

Konular: Cerrahi
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA Kara E, İNKAYA A, AYDIN HAKLI D, DEMİRKAN S, ÜNAL S (2019). Polypharmacy and drug-related problems among people living with HIV/AIDS: a singlecenter experience. , 222 - 229. 10.3906/sag-1807-295
Chicago Kara Emre,İNKAYA AHMET ÇAĞKAN,AYDIN HAKLI DUYGU,DEMİRKAN SALİH KUTAY,ÜNAL Serhat Polypharmacy and drug-related problems among people living with HIV/AIDS: a singlecenter experience. (2019): 222 - 229. 10.3906/sag-1807-295
MLA Kara Emre,İNKAYA AHMET ÇAĞKAN,AYDIN HAKLI DUYGU,DEMİRKAN SALİH KUTAY,ÜNAL Serhat Polypharmacy and drug-related problems among people living with HIV/AIDS: a singlecenter experience. , 2019, ss.222 - 229. 10.3906/sag-1807-295
AMA Kara E,İNKAYA A,AYDIN HAKLI D,DEMİRKAN S,ÜNAL S Polypharmacy and drug-related problems among people living with HIV/AIDS: a singlecenter experience. . 2019; 222 - 229. 10.3906/sag-1807-295
Vancouver Kara E,İNKAYA A,AYDIN HAKLI D,DEMİRKAN S,ÜNAL S Polypharmacy and drug-related problems among people living with HIV/AIDS: a singlecenter experience. . 2019; 222 - 229. 10.3906/sag-1807-295
IEEE Kara E,İNKAYA A,AYDIN HAKLI D,DEMİRKAN S,ÜNAL S "Polypharmacy and drug-related problems among people living with HIV/AIDS: a singlecenter experience." , ss.222 - 229, 2019. 10.3906/sag-1807-295
ISNAD Kara, Emre vd. "Polypharmacy and drug-related problems among people living with HIV/AIDS: a singlecenter experience". (2019), 222-229. https://doi.org/10.3906/sag-1807-295
APA Kara E, İNKAYA A, AYDIN HAKLI D, DEMİRKAN S, ÜNAL S (2019). Polypharmacy and drug-related problems among people living with HIV/AIDS: a singlecenter experience. Turkish Journal of Medical Sciences, 49(1), 222 - 229. 10.3906/sag-1807-295
Chicago Kara Emre,İNKAYA AHMET ÇAĞKAN,AYDIN HAKLI DUYGU,DEMİRKAN SALİH KUTAY,ÜNAL Serhat Polypharmacy and drug-related problems among people living with HIV/AIDS: a singlecenter experience. Turkish Journal of Medical Sciences 49, no.1 (2019): 222 - 229. 10.3906/sag-1807-295
MLA Kara Emre,İNKAYA AHMET ÇAĞKAN,AYDIN HAKLI DUYGU,DEMİRKAN SALİH KUTAY,ÜNAL Serhat Polypharmacy and drug-related problems among people living with HIV/AIDS: a singlecenter experience. Turkish Journal of Medical Sciences, vol.49, no.1, 2019, ss.222 - 229. 10.3906/sag-1807-295
AMA Kara E,İNKAYA A,AYDIN HAKLI D,DEMİRKAN S,ÜNAL S Polypharmacy and drug-related problems among people living with HIV/AIDS: a singlecenter experience. Turkish Journal of Medical Sciences. 2019; 49(1): 222 - 229. 10.3906/sag-1807-295
Vancouver Kara E,İNKAYA A,AYDIN HAKLI D,DEMİRKAN S,ÜNAL S Polypharmacy and drug-related problems among people living with HIV/AIDS: a singlecenter experience. Turkish Journal of Medical Sciences. 2019; 49(1): 222 - 229. 10.3906/sag-1807-295
IEEE Kara E,İNKAYA A,AYDIN HAKLI D,DEMİRKAN S,ÜNAL S "Polypharmacy and drug-related problems among people living with HIV/AIDS: a singlecenter experience." Turkish Journal of Medical Sciences, 49, ss.222 - 229, 2019. 10.3906/sag-1807-295
ISNAD Kara, Emre vd. "Polypharmacy and drug-related problems among people living with HIV/AIDS: a singlecenter experience". Turkish Journal of Medical Sciences 49/1 (2019), 222-229. https://doi.org/10.3906/sag-1807-295