The efficiency of low-dose hepatitis B immunoglobulin plus nucleos(t)ide analogs in preventing posttransplant hepatitis B virus recurrence
Yıl: 2019 Cilt: 49 Sayı: 4 Sayfa Aralığı: 1019 - 1024 Metin Dili: İngilizce DOI: 10.3906/sag-1808-86 İndeks Tarihi: 12-05-2020
The efficiency of low-dose hepatitis B immunoglobulin plus nucleos(t)ide analogs in preventing posttransplant hepatitis B virus recurrence
Öz: Background/aim: In this study, the efficiency of using low-dose hepatitis B immunoglobulin (HBIG) plus antiviral treatment accordingto individual needs has been evaluated in posttransplant hepatitis B virus (HBV) patients.Materials and methods: We retrospectively evaluated 179 patients who were admitted between 2009 and 2014. Five thousand IUintravenous HBIG was given in the anhepatic phase, and 400 IU/day intramuscular (IM) HBIG was given in the posttransplant period.After HBsAg seroconversion, 400 IU IM HBIG was continued as prophylaxis every two weeks.Results: The average follow-up period was 26 (2–65) months. Seventy patients had hepatocellular carcinoma (HCC). The HBVrecurrence was 4.5% in the first year, and 5.8% in the third year. The HBsAg became negative in 11 (2–63) days, and anti-HBs becamepositive in 9 (1–31) days. HBsAg positivity occurred in 6 patients during the follow-up period. Five of these patients were those whounderwent transplantation due to HCC. In 5 of the HCC patients, in whom HBsAg became positive, tumor recurrence was observedafter 0.3–9.9 months. HBsAg positivity was more frequently detected in patients with HCC (P = 0.009).Conclusion: The HBV recurrence should be evaluated as a predictor of the HCC recurrence in patients who were transplanted due toHCC.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | vatansever s, FARAJOV R, YILMAZ H, Zeytunlu M, kılıç m (2019). The efficiency of low-dose hepatitis B immunoglobulin plus nucleos(t)ide analogs in preventing posttransplant hepatitis B virus recurrence. , 1019 - 1024. 10.3906/sag-1808-86 |
| Chicago | vatansever sezgin,FARAJOV Rasim,YILMAZ Hüseyin Cahit,Zeytunlu Murat,kılıç murat The efficiency of low-dose hepatitis B immunoglobulin plus nucleos(t)ide analogs in preventing posttransplant hepatitis B virus recurrence. (2019): 1019 - 1024. 10.3906/sag-1808-86 |
| MLA | vatansever sezgin,FARAJOV Rasim,YILMAZ Hüseyin Cahit,Zeytunlu Murat,kılıç murat The efficiency of low-dose hepatitis B immunoglobulin plus nucleos(t)ide analogs in preventing posttransplant hepatitis B virus recurrence. , 2019, ss.1019 - 1024. 10.3906/sag-1808-86 |
| AMA | vatansever s,FARAJOV R,YILMAZ H,Zeytunlu M,kılıç m The efficiency of low-dose hepatitis B immunoglobulin plus nucleos(t)ide analogs in preventing posttransplant hepatitis B virus recurrence. . 2019; 1019 - 1024. 10.3906/sag-1808-86 |
| Vancouver | vatansever s,FARAJOV R,YILMAZ H,Zeytunlu M,kılıç m The efficiency of low-dose hepatitis B immunoglobulin plus nucleos(t)ide analogs in preventing posttransplant hepatitis B virus recurrence. . 2019; 1019 - 1024. 10.3906/sag-1808-86 |
| IEEE | vatansever s,FARAJOV R,YILMAZ H,Zeytunlu M,kılıç m "The efficiency of low-dose hepatitis B immunoglobulin plus nucleos(t)ide analogs in preventing posttransplant hepatitis B virus recurrence." , ss.1019 - 1024, 2019. 10.3906/sag-1808-86 |
| ISNAD | vatansever, sezgin vd. "The efficiency of low-dose hepatitis B immunoglobulin plus nucleos(t)ide analogs in preventing posttransplant hepatitis B virus recurrence". (2019), 1019-1024. https://doi.org/10.3906/sag-1808-86 |
| APA | vatansever s, FARAJOV R, YILMAZ H, Zeytunlu M, kılıç m (2019). The efficiency of low-dose hepatitis B immunoglobulin plus nucleos(t)ide analogs in preventing posttransplant hepatitis B virus recurrence. Turkish Journal of Medical Sciences, 49(4), 1019 - 1024. 10.3906/sag-1808-86 |
| Chicago | vatansever sezgin,FARAJOV Rasim,YILMAZ Hüseyin Cahit,Zeytunlu Murat,kılıç murat The efficiency of low-dose hepatitis B immunoglobulin plus nucleos(t)ide analogs in preventing posttransplant hepatitis B virus recurrence. Turkish Journal of Medical Sciences 49, no.4 (2019): 1019 - 1024. 10.3906/sag-1808-86 |
| MLA | vatansever sezgin,FARAJOV Rasim,YILMAZ Hüseyin Cahit,Zeytunlu Murat,kılıç murat The efficiency of low-dose hepatitis B immunoglobulin plus nucleos(t)ide analogs in preventing posttransplant hepatitis B virus recurrence. Turkish Journal of Medical Sciences, vol.49, no.4, 2019, ss.1019 - 1024. 10.3906/sag-1808-86 |
| AMA | vatansever s,FARAJOV R,YILMAZ H,Zeytunlu M,kılıç m The efficiency of low-dose hepatitis B immunoglobulin plus nucleos(t)ide analogs in preventing posttransplant hepatitis B virus recurrence. Turkish Journal of Medical Sciences. 2019; 49(4): 1019 - 1024. 10.3906/sag-1808-86 |
| Vancouver | vatansever s,FARAJOV R,YILMAZ H,Zeytunlu M,kılıç m The efficiency of low-dose hepatitis B immunoglobulin plus nucleos(t)ide analogs in preventing posttransplant hepatitis B virus recurrence. Turkish Journal of Medical Sciences. 2019; 49(4): 1019 - 1024. 10.3906/sag-1808-86 |
| IEEE | vatansever s,FARAJOV R,YILMAZ H,Zeytunlu M,kılıç m "The efficiency of low-dose hepatitis B immunoglobulin plus nucleos(t)ide analogs in preventing posttransplant hepatitis B virus recurrence." Turkish Journal of Medical Sciences, 49, ss.1019 - 1024, 2019. 10.3906/sag-1808-86 |
| ISNAD | vatansever, sezgin vd. "The efficiency of low-dose hepatitis B immunoglobulin plus nucleos(t)ide analogs in preventing posttransplant hepatitis B virus recurrence". Turkish Journal of Medical Sciences 49/4 (2019), 1019-1024. https://doi.org/10.3906/sag-1808-86 |
