Efficiency of inferior petrosal sinus sampling in the diagnosis of Cushing’s disease and comparison with magnetic resonance imaging
Yıl: 2019 Cilt: 6 Sayı: 1 Sayfa Aralığı: 53 - 58 Metin Dili: İngilizce DOI: 10.14744/nci.2018.83584 İndeks Tarihi: 20-05-2020
Efficiency of inferior petrosal sinus sampling in the diagnosis of Cushing’s disease and comparison with magnetic resonance imaging
Öz: OBJECTIVE: The purpose of this study is to assess the efficiency of inferior petrosal sinus sampling (IPSS) in the diagnosisof adrenocorticotropic hormone-dependent Cushing’s disease and to compare it with magnetic resonance imaging (MRI).METHODS: The diagnostic efficiency of IPSS in the differentiation of pituitary Cushing’s disease from ectopic Cushing’s disease was retrospectively evaluated in 37 patients who had IPSS in our clinic. Six patients were excluded from the study dueto missing data. Hypophysis MRI examinations of 31 patients before IPSS were also evaluated. The contributions of MRI andIPSS to the detection of pituitary adenoma and the determination of lateralization were researched.RESULTS: Bilateral IPSS was successfully performed in 30 patients of the 31 patients in the study group. The sensitivity,specificity, positive predictive value, negative predictive value, and accuracy of IPSS in differentiating between central andectopic Cushing’s syndrome before corticotrophin-releasing hormone (CRH) stimulation were 93.3%, 100%, 100%, 33.3%,and 93%, respectively, whereas after CRH stimulation were 100%, 100%, 100%, 100%, and 100%, respectively. The accuracy of both the rates was significantly higher compared with MRI.CONCLUSION: IPSS has the highest diagnostic efficiency in differentiating central Cushing’s disease from ectopic Cushing’sdisease.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
- 1. Newell-Price J, Trainer P, Besser M, Grossman A. The diagnosis and differential diagnosis of Cushing’s syndrome and pseudo-Cushing’s states. Endocr Rev 1998;19:647–72. [CrossRef ]
- 2. Buchfelder M, Nistor R, Fahlbusch R, Huk WJ. The accuracy of CT and MR evaluation of the sella turcica for detection of adrenocorticotropic hormone-secreting adenomas in Cushing disease. AJNR Am J Neuroradiol 1993;14:1183–90.
- 3. Yogi-Morren D, Habra MA, Faiman C, Bena J, Hatipoglu B, Kennedy L, et al. Pituitary MRI findings in patients with pituitary and ectopic acth-dependent Cushing syndrome: Does a 6-mm pituitary tumor size cut-off value exclude ectopic acth syndrome? Endocr Prac 2015;21:1098–103. [CrossRef ]
- 4. Wiggam MI, Heaney AP, McIlrath EM, McCance DR, Sheridan B, Hadden DR, et al. Bilateral inferior petrosal sinus sampling in the differential diagnosis of adrenocorticotropin-dependent Cushing’s syndrome: A comparison with other diagnostic tests. J Clin Endocrinol Metab 2000;85:1525–32. [CrossRef ]
- 5. Kaskarelis IS, Tsatalou EG, Benakis SV, Malagari K, Komninos I, Vassiliadi D, et al. Bilateral inferior petrosal sinuses sampling in the routine investigation of Cushing’s syndrome: A comparison with MRI. AJR Am J Roentgenol 2006;187:562–70. [CrossRef ]
- 6. Colao A, Faggiano A, Pivonello R, Pecori Giraldi F, Cavagnini F, Lombardi G, et al. Inferior petrosal sinus sampling in the differential diagnosis of Cushing’s syndrome: Results of an Italian multicenter study. Eur J Endocrinol 2001;144:499–507. [CrossRef ]
- 7. Deipolyi A, Karaosmanoğlu A, Habito C, Brannan S, Wicky S, Hirsch J, et al. The role of bilateral inferior petrosal sinus sampling in the diagnostic evaluation of Cushing syndrome. Diagn Interv Radiol 2012;18:132–8.
- 8. Lefournier V, Martinie M, Vasdev A, Bessou P, Passagia JG, LabatMoleur F, et al. Accuracy of bilateral inferior petrosal or cavernous sinuses sampling in predicting the lateralization of Cushing’s disease pituitary microadenoma: Influence of catheter position and anatomy of 58 North Clin Istanb venous drainage. J Clin Endocrinol Metab 2003;88:196–203. [CrossRef ]
- 9. Bonelli FS, Huston J 3rd, Meyer FB, Carpenter PC. Venous subarachnoid hemorrhage after inferior petrosal sinus sampling for adrenocorticotropic hormone. AJNR Am J Neuroradiol 1999;20:306–7.
- 10. Gandhi CD, Meyer SA, Patel AB, Johnson DM, Post KD. Neurologic complications of inferior petrosal sinus sampling. AJNR Am J Neuroradiol 2008;29:760–5. [CrossRef ]
- 11. Blevins LS Jr., Clark RV, Owens DS. Thromboembolic complications after inferior petrosal sinus sampling in patients with Cushing’s syndrome. Endocr Pract 1998;4:365–7. [CrossRef ]
- 12. Swearingen B, Katznelson L, Miller K, Grinspoon S, Waltman A, Dorer DJ, et al. Diagnostic errors after inferior petrosal sinus sampling. J Clin Endocrinol Metab 2004;89:3752–63. [CrossRef ]
- 13. Doppman JL, Oldfield EH, Nieman LK. Bilateral sampling of the internal jugular vein to distinguish between mechanisms of adrenocorticotropic hormone-dependent Cushing syndrome. Ann Intern Med 1998;128:33–6. [CrossRef ]
- 14. Ilias I, Chang R, Pacak K, Oldfield EH, Wesley R, Doppman J, et al. Jugular venous sampling: An alternative to petrosal sinus sampling for the diagnostic evaluation of adrenocorticotropic hormone-dependent Cushing’s syndrome. J Clin Endocrinol Metab 2004;89:3795–800.
| APA | BEKCİ T (2019). Efficiency of inferior petrosal sinus sampling in the diagnosis of Cushing’s disease and comparison with magnetic resonance imaging. , 53 - 58. 10.14744/nci.2018.83584 |
| Chicago | BEKCİ Tümay Efficiency of inferior petrosal sinus sampling in the diagnosis of Cushing’s disease and comparison with magnetic resonance imaging. (2019): 53 - 58. 10.14744/nci.2018.83584 |
| MLA | BEKCİ Tümay Efficiency of inferior petrosal sinus sampling in the diagnosis of Cushing’s disease and comparison with magnetic resonance imaging. , 2019, ss.53 - 58. 10.14744/nci.2018.83584 |
| AMA | BEKCİ T Efficiency of inferior petrosal sinus sampling in the diagnosis of Cushing’s disease and comparison with magnetic resonance imaging. . 2019; 53 - 58. 10.14744/nci.2018.83584 |
| Vancouver | BEKCİ T Efficiency of inferior petrosal sinus sampling in the diagnosis of Cushing’s disease and comparison with magnetic resonance imaging. . 2019; 53 - 58. 10.14744/nci.2018.83584 |
| IEEE | BEKCİ T "Efficiency of inferior petrosal sinus sampling in the diagnosis of Cushing’s disease and comparison with magnetic resonance imaging." , ss.53 - 58, 2019. 10.14744/nci.2018.83584 |
| ISNAD | BEKCİ, Tümay. "Efficiency of inferior petrosal sinus sampling in the diagnosis of Cushing’s disease and comparison with magnetic resonance imaging". (2019), 53-58. https://doi.org/10.14744/nci.2018.83584 |
| APA | BEKCİ T (2019). Efficiency of inferior petrosal sinus sampling in the diagnosis of Cushing’s disease and comparison with magnetic resonance imaging. İstanbul Kuzey Klinikleri, 6(1), 53 - 58. 10.14744/nci.2018.83584 |
| Chicago | BEKCİ Tümay Efficiency of inferior petrosal sinus sampling in the diagnosis of Cushing’s disease and comparison with magnetic resonance imaging. İstanbul Kuzey Klinikleri 6, no.1 (2019): 53 - 58. 10.14744/nci.2018.83584 |
| MLA | BEKCİ Tümay Efficiency of inferior petrosal sinus sampling in the diagnosis of Cushing’s disease and comparison with magnetic resonance imaging. İstanbul Kuzey Klinikleri, vol.6, no.1, 2019, ss.53 - 58. 10.14744/nci.2018.83584 |
| AMA | BEKCİ T Efficiency of inferior petrosal sinus sampling in the diagnosis of Cushing’s disease and comparison with magnetic resonance imaging. İstanbul Kuzey Klinikleri. 2019; 6(1): 53 - 58. 10.14744/nci.2018.83584 |
| Vancouver | BEKCİ T Efficiency of inferior petrosal sinus sampling in the diagnosis of Cushing’s disease and comparison with magnetic resonance imaging. İstanbul Kuzey Klinikleri. 2019; 6(1): 53 - 58. 10.14744/nci.2018.83584 |
| IEEE | BEKCİ T "Efficiency of inferior petrosal sinus sampling in the diagnosis of Cushing’s disease and comparison with magnetic resonance imaging." İstanbul Kuzey Klinikleri, 6, ss.53 - 58, 2019. 10.14744/nci.2018.83584 |
| ISNAD | BEKCİ, Tümay. "Efficiency of inferior petrosal sinus sampling in the diagnosis of Cushing’s disease and comparison with magnetic resonance imaging". İstanbul Kuzey Klinikleri 6/1 (2019), 53-58. https://doi.org/10.14744/nci.2018.83584 |
