POLYPHARMACY AND POTENTIALLY INAPPROPRIATE MEDICATION USE IN GERIATRIC PATIENTS PRESENTING TO THE EMERGENCY DEPARTMENT

Sahin, Serkan; ATMACA TEMREL, TUĞBA

POLYPHARMACY AND POTENTIALLY INAPPROPRIATE MEDICATION USE IN GERIATRIC PATIENTS PRESENTING TO THE EMERGENCY DEPARTMENT

TUĞBA ATMACA TEMREL, (Sağlık Bilimleri Üniversitesi)

Serkan ŞAHİN (Bolu Abant İzzet Baysal Devlet Hastanesi)

Türk Geriatri Dergisi

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Yıl: 2019 Cilt: 22 Sayı: 1 Sayfa Aralığı: 25 - 31 Metin Dili: İngilizce İndeks Tarihi: 20-05-2020

POLYPHARMACY AND POTENTIALLY INAPPROPRIATE MEDICATION USE IN GERIATRIC PATIENTS PRESENTING TO THE EMERGENCY DEPARTMENT

Öz:

Introduction: A potentially inappropriate medication is defined as a drug that has higher adverse effects when compared with the clinical benefit, although a safer or more efficient alternative treatment exists given the same situation. This cross-sectional study aimed to assess the presence of polypharmacy (use of five or more drugs) in older patients aged ≥65 years.Materials and Method: Geriatric patients presenting to the emergency department between January and March 2018 who had been prescribed five or more drugs were evaluated with a questionnaire for potentially inappropriate medication and polypharmacy. The questionnaire comprised demographic data, chronic diseases affecting elderly patients, and chronic drugs used according to the Beers criteria (2015 version) for elderly adults.Results: The study cohort consisted of 144 patients (56 males, 88 females). The mean age of participants was 77.23±7.94 years. The most common chronic diseases were hypertension (22.5%), coronary artery disease (15.1%), and diabetes (10.7%). The three most commonly prescribed drugs were aspirin (10.8%), an angiotensin receptor blocker + thiazide (9.8%), and beta blockers (9.8%). The average number of medications used was 5.22±2.56. Polypharmacy was found in 80 patients (55.6%) whereas potentially inappropriate medication use was determined in 78 (54.2%) patients.Conclusions: Both polypharmacy and potentially inappropriate medication use were found to have a high frequency in our study group. We found the use of potentially inappropriate medication to be significantly higher in patients with polypharmacy. The most used potentially inappropriate medications were proton pump inhibitors and non-steroidal anti-inflammatory drugs.

Anahtar Kelime:

Konular: Cerrahi

ACİL SERVİSE BAŞVURAN GERİATRİ YAŞ GRUBUNDAKİ HASTALARDA POLİFARMASİ VE POTANSİYEL UYGUN OLMAYAN İLAÇ KULLANIMI

Öz:

Giriş: Potansiyel olarak uygun olmayan bir ilaç, aynı durum göz önüne alındığında daha güvenli veya daha etkili bir alternatif tedavi mevcut olmasına rağmen, klinik fayda ile tartıldığında daha yüksek yan etkileri olan bir ilaç olarak tanımlanmaktadır. Bu kesitsel çalışma, 65 yaş üstü yaşlı hastalarda polifarmasinin (beş veya daha fazla ilacın kullanımı) varlığını değerlendirmeyi amaçlamıştır. Gereç ve Yöntem: Ocak ve Mart 2018 tarihleri arasında acil servise başvuran geriatri yaş grubundaki hastaların polifarmasi durumu ve potansiyel olarak uygun olmayan ilaç kullanımı durumu oluşturulan anket form ile değerlendirildi. Anket formda demografik veriler, kronik hastalıklar ve yaşlılar için Beers kriterlerine göre (2015 versiyon) kronik ilaç kullanımı yer almaktadır. Bulgular: Çalışma grubu, 144 hastadan oluşmaktaydı (56 erkek, 88 kadın). Katılımcıların yaş ortalaması 77.23±7.94 yıldı. En sık görülen kronik hastalıklar hipertansiyon (%22.5), koroner arter hastalığı (%15.1) ve diyabet (%10.7) idi. En sık kullanılan üç ilaç, aspirin (%10.8), anjiyotensin reseptör bloker + tiyazid (%9.8) ve beta blokerleridir (%9.8). Kullanılan ilaç sayısı ortalaması 5.22±2.56 idi. 80 hastada polifarmasi (%55,6) bulunurken, 78 (%54.2) hastada potansiyel olarak uygun olmayan ilaç kullanımı saptandı. Sonuç: Hem polifarmasi hem de potansiyel olarak uygun olmayan ilaç kullanımının çalışma grubumuzda yüksek sıklığa sahip olduğu bulundu. En çok kullanılan potansiyel uygun olmayan ilaç, proton pompası inhibitörleri ve non-steroidal antiinflamatuar ilaçlar idi.

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	ATMACA TEMREL T, Sahin S (2019). POLYPHARMACY AND POTENTIALLY INAPPROPRIATE MEDICATION USE IN GERIATRIC PATIENTS PRESENTING TO THE EMERGENCY DEPARTMENT. , 25 - 31.
Chicago	ATMACA TEMREL TUĞBA,Sahin Serkan POLYPHARMACY AND POTENTIALLY INAPPROPRIATE MEDICATION USE IN GERIATRIC PATIENTS PRESENTING TO THE EMERGENCY DEPARTMENT. (2019): 25 - 31.
MLA	ATMACA TEMREL TUĞBA,Sahin Serkan POLYPHARMACY AND POTENTIALLY INAPPROPRIATE MEDICATION USE IN GERIATRIC PATIENTS PRESENTING TO THE EMERGENCY DEPARTMENT. , 2019, ss.25 - 31.
AMA	ATMACA TEMREL T,Sahin S POLYPHARMACY AND POTENTIALLY INAPPROPRIATE MEDICATION USE IN GERIATRIC PATIENTS PRESENTING TO THE EMERGENCY DEPARTMENT. . 2019; 25 - 31.
Vancouver	ATMACA TEMREL T,Sahin S POLYPHARMACY AND POTENTIALLY INAPPROPRIATE MEDICATION USE IN GERIATRIC PATIENTS PRESENTING TO THE EMERGENCY DEPARTMENT. . 2019; 25 - 31.
IEEE	ATMACA TEMREL T,Sahin S "POLYPHARMACY AND POTENTIALLY INAPPROPRIATE MEDICATION USE IN GERIATRIC PATIENTS PRESENTING TO THE EMERGENCY DEPARTMENT." , ss.25 - 31, 2019.
ISNAD	ATMACA TEMREL, TUĞBA - Sahin, Serkan. "POLYPHARMACY AND POTENTIALLY INAPPROPRIATE MEDICATION USE IN GERIATRIC PATIENTS PRESENTING TO THE EMERGENCY DEPARTMENT". (2019), 25-31.

APA	ATMACA TEMREL T, Sahin S (2019). POLYPHARMACY AND POTENTIALLY INAPPROPRIATE MEDICATION USE IN GERIATRIC PATIENTS PRESENTING TO THE EMERGENCY DEPARTMENT. Türk Geriatri Dergisi, 22(1), 25 - 31.
Chicago	ATMACA TEMREL TUĞBA,Sahin Serkan POLYPHARMACY AND POTENTIALLY INAPPROPRIATE MEDICATION USE IN GERIATRIC PATIENTS PRESENTING TO THE EMERGENCY DEPARTMENT. Türk Geriatri Dergisi 22, no.1 (2019): 25 - 31.
MLA	ATMACA TEMREL TUĞBA,Sahin Serkan POLYPHARMACY AND POTENTIALLY INAPPROPRIATE MEDICATION USE IN GERIATRIC PATIENTS PRESENTING TO THE EMERGENCY DEPARTMENT. Türk Geriatri Dergisi, vol.22, no.1, 2019, ss.25 - 31.
AMA	ATMACA TEMREL T,Sahin S POLYPHARMACY AND POTENTIALLY INAPPROPRIATE MEDICATION USE IN GERIATRIC PATIENTS PRESENTING TO THE EMERGENCY DEPARTMENT. Türk Geriatri Dergisi. 2019; 22(1): 25 - 31.
Vancouver	ATMACA TEMREL T,Sahin S POLYPHARMACY AND POTENTIALLY INAPPROPRIATE MEDICATION USE IN GERIATRIC PATIENTS PRESENTING TO THE EMERGENCY DEPARTMENT. Türk Geriatri Dergisi. 2019; 22(1): 25 - 31.
IEEE	ATMACA TEMREL T,Sahin S "POLYPHARMACY AND POTENTIALLY INAPPROPRIATE MEDICATION USE IN GERIATRIC PATIENTS PRESENTING TO THE EMERGENCY DEPARTMENT." Türk Geriatri Dergisi, 22, ss.25 - 31, 2019.
ISNAD	ATMACA TEMREL, TUĞBA - Sahin, Serkan. "POLYPHARMACY AND POTENTIALLY INAPPROPRIATE MEDICATION USE IN GERIATRIC PATIENTS PRESENTING TO THE EMERGENCY DEPARTMENT". Türk Geriatri Dergisi 22/1 (2019), 25-31.