PREDICTING MALIGNANCY IN CERVICAL LYMPH NODE: CLINICAL RESULTS

ERBEK, Selim Sermed; HETEMOĞLU, Elif Koçlu

PREDICTING MALIGNANCY IN CERVICAL LYMPH NODE: CLINICAL RESULTS

Elif Koçlu HETEMOĞLU, (Başkent Üniversitesi)

Selim Sermed ERBEK (Başkent Üniversitesi)

KBB-Forum

3 1

Yıl: 2019 Cilt: 18 Sayı: 1 Sayfa Aralığı: 28 - 32 Metin Dili: İngilizce İndeks Tarihi: 22-05-2020

PREDICTING MALIGNANCY IN CERVICAL LYMPH NODE: CLINICAL RESULTS

Öz:

Background: The history of the patient, examination findings and imaging modalities are important to determine the etiological factorsin lymphadenopathies, A good knowledge of the predictive values of malignancy, prevents loss of time and unnecessary surgeries. The aimof this study was to evaluate the pathology results of patients who underwent excisional lymph node biopsy and to examine the parametersthat can be used in predicting malignancy.Methods: Patients who underwent excisional lymph node biopsy due to cervical lymphadenopathy were included in the study andpatient files were retrospectively scanned. The demographic information of the patients and region, side, size, consistency, and localizationof the lymph node were recorded. Preoperative screening techniques, postoperative complications and pathological diagnosis were alsorecorded. Parameters that can be used to predict malignancy, were determined from these data.Results: The study included a total of 133 patients, comprising 60 (45.1%) males and 73 (54.9%) females. Malignant lesions were foundat a significantly higher rate in patients aged >40 years (p=0.003). Supraclavicular, rigid and ≥3 cm lymphadenopathies had a high risk ofmalignancy, although not at a statistically significant level.Conclusion: Age is a parameter that can be used in the prediction of malignancy in cervical lymphadenopathies

Anahtar Kelime:

Konular: Kulak, Burun, Boğaz

SERVİKAL LENF NODUNDA MALİGNİTE PREDİKSİYONU, KLİNİK SONUÇLARIMIZ

Öz:

Amaç: Lenfadenopatilerde etyolojik faktörün değerlendirilmesinde hastanın anamnezi, muayene bulguları ve görüntüleme yöntemlerinin önemi büyüktür. Malignite prediktif değerlerinin iyi bilinmesi, gereksiz cerrahileri önlediği gibi hastaların vakit kaybetmesini de engeller. Bu çalışmamızın amacı eksizyonel lenf nodu biyopsisi işlemi uygulanan hastaların patoloji sonuçlarını değerlendirerek malignite prediksiyonunda kullanılabilecek parametreleri incelemektir. Metod: Servikal lenfadenopati sebebi ile eksizyonel lenf nodu biyopsisi uygulanan hastalar çalışmaya dahil edilerek dosyaları retrospektif tarandı. Hastaların demografik bilgileri ve lenf nodunun bölgesi, tarafı, boyutu, kıvamı, lokalizasyonu kaydedildi. Hastalara uygulanan görüntüleme yöntemleri postoperatif komplikasyonlar ve patolojik tanılar not edildi. Bu verilerden malignite prediksiyonunda kullanılabilecek parametreler saptandı. Bulgular: 60` ı (%45.1) erkek, 73`ü (%54.9) kadın, toplam 133 hasta çalışmaya dahil edildi. >40 yaş hastalarda malign lezyonlar istatistiksel olarak anlamlı oranda yüksek bulundu (p=0.003). Ayrıca supraklaviküler alanda yer alan, sert kıvamlı ve ≥3 cm lenfadenopatilerde istatistiksel olarak anlamlı olmamakla beraber daha yüksek oranda malignite görüldü. Sonuç: Servikal lenfadenopatisi olan hastalarda yaş, malignite prediksiyonunda kullanılabilecek bir parametredir.

Anahtar Kelime:

Konular: Kulak, Burun, Boğaz

Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık

1. http://emedicine.medscape.com/article/937855-overview
2. Twist CJ, Link MP. Assesment of lymphadenopathy in children. Pediatr Clin North Am 2000; 49: 1009-1025.
3. Camitta BM, Behrmann RE, Kliegman RM, Jenson HB. The Lymphatic System. In: Nelson Textbook of Pediatrics Eds: (17 th ed), Saunders Company USA 2004; 1677-1678.
4. http://emedicine.medscape.com/article/956340-overview
5. Lang S, Kansy B. Cervical lymph node diseases in children. GMS Current Topics in Otorhinolaryngology, Head and Neck Surgery. 2014;13:Doc08.
6. Miller DR, Baehner RL. Hematologic malignancies: leukemia and lymphoma (Differential diagnosis of lymphadenopathy) eds. Blood Diseases of Infancy and Childhood.Mosby Inc;1995.745-9.
7. Bhattacharya N. Predictive factors.for neoplasia and malignancy in a neck mass. Arch Otolaryngol Head Neck Surg. 1999;125(3):303-7.
8. Ekşi E, Yerli H, Y ılmaz İ. Erişkin Boyun Lenfadenopatilerinde Yaklaş ım veAntibiyotik Tedavisi: 3 Olgu Sunumu. ACU Sağl ık Bil Derg2010;1(3):170-171
9. Khillan R, Sidhu G, Axiotis C, Braverman AS. Fine needle aspiration (FNA) cytology for diagnosis of cervical lymphadenopathy. Int J Hematol 2012;95:282-284.
10. Savage SA, Wotherspoon HA, Fitzsimons EJ, Mackenzie K. Cervi¬cal lymphadenopathy resulting in a diagnosis of lymphoma. Scott Med J 2008;53:13-16.
11. Celenk F, Gulsen S, Baysal E, Aytac I, Kul S, Kanl ıkama M.Predictive factors for malignancy in patients with persistent cervical lymphadenopathy. Eur Arch Otorhinolaryngol 2016;273(1):251-6.
12. Al Kadah B, Popov HH, Schick B, Knobber D. Cervical lymphadenopathy: study of 251 patients. Eur Arch Otorhinolaryngol 2015;272:745-752.
13. Chau I, Kelleher MT, Cunningham D, Norman AR, Wotherspoon A, Trott P, et al. Rapid access multidisciplinary lymph node diagnostic clinic: analysis of 550 patients. Br J Cancer 2003;88:354-361.
14. Locke R, Comfort R, Kubba H. When does an enlarged cervical lymph node in a child need excision? A systematic review. Int J Pediatr Otorhinolaryngol. 2014;78(3):393-401.
15. Nolder AR. Paediatric cervical lymphadenopathy: when to biopsy? Curr Opin Otolaryngol Head Neck Surg. 2013;21(6):567-70.
16. Doğan S, Y ıldırım A, Erbakırc ı R, Okur A, Cağl ı S, Mavili E, et al. The Role of Ultrasonography for Differentiating and Management of Malignant Cervical Lymph Nodes. Eur J Gen Med 2016;13(1):7-15

APA	HETEMOĞLU E, ERBEK S (2019). PREDICTING MALIGNANCY IN CERVICAL LYMPH NODE: CLINICAL RESULTS. , 28 - 32.
Chicago	HETEMOĞLU Elif Koçlu,ERBEK Selim Sermed PREDICTING MALIGNANCY IN CERVICAL LYMPH NODE: CLINICAL RESULTS. (2019): 28 - 32.
MLA	HETEMOĞLU Elif Koçlu,ERBEK Selim Sermed PREDICTING MALIGNANCY IN CERVICAL LYMPH NODE: CLINICAL RESULTS. , 2019, ss.28 - 32.
AMA	HETEMOĞLU E,ERBEK S PREDICTING MALIGNANCY IN CERVICAL LYMPH NODE: CLINICAL RESULTS. . 2019; 28 - 32.
Vancouver	HETEMOĞLU E,ERBEK S PREDICTING MALIGNANCY IN CERVICAL LYMPH NODE: CLINICAL RESULTS. . 2019; 28 - 32.
IEEE	HETEMOĞLU E,ERBEK S "PREDICTING MALIGNANCY IN CERVICAL LYMPH NODE: CLINICAL RESULTS." , ss.28 - 32, 2019.
ISNAD	HETEMOĞLU, Elif Koçlu - ERBEK, Selim Sermed. "PREDICTING MALIGNANCY IN CERVICAL LYMPH NODE: CLINICAL RESULTS". (2019), 28-32.

APA	HETEMOĞLU E, ERBEK S (2019). PREDICTING MALIGNANCY IN CERVICAL LYMPH NODE: CLINICAL RESULTS. KBB-Forum, 18(1), 28 - 32.
Chicago	HETEMOĞLU Elif Koçlu,ERBEK Selim Sermed PREDICTING MALIGNANCY IN CERVICAL LYMPH NODE: CLINICAL RESULTS. KBB-Forum 18, no.1 (2019): 28 - 32.
MLA	HETEMOĞLU Elif Koçlu,ERBEK Selim Sermed PREDICTING MALIGNANCY IN CERVICAL LYMPH NODE: CLINICAL RESULTS. KBB-Forum, vol.18, no.1, 2019, ss.28 - 32.
AMA	HETEMOĞLU E,ERBEK S PREDICTING MALIGNANCY IN CERVICAL LYMPH NODE: CLINICAL RESULTS. KBB-Forum. 2019; 18(1): 28 - 32.
Vancouver	HETEMOĞLU E,ERBEK S PREDICTING MALIGNANCY IN CERVICAL LYMPH NODE: CLINICAL RESULTS. KBB-Forum. 2019; 18(1): 28 - 32.
IEEE	HETEMOĞLU E,ERBEK S "PREDICTING MALIGNANCY IN CERVICAL LYMPH NODE: CLINICAL RESULTS." KBB-Forum, 18, ss.28 - 32, 2019.
ISNAD	HETEMOĞLU, Elif Koçlu - ERBEK, Selim Sermed. "PREDICTING MALIGNANCY IN CERVICAL LYMPH NODE: CLINICAL RESULTS". KBB-Forum 18/1 (2019), 28-32.