Biological activity and chemical composition of the essential oil of Nepeta cataria L

ASHRAFI, Behnam; RAMAK, Parvin; TALEI, Gholam Reza; EZATPOUR, Behrouz

Biological activity and chemical composition of the essential oil of Nepeta cataria L

Behnam ASHRAFI, (Islamic Azad University)

Parvin RAMAK, (Lorestan Agricultrural and Natural Resources Research and Education Center,)

Behrouz EZATPOUR, (Diğer)

Gholam Reza TALEI (Diğer)

Journal of research in pharmacy (online)

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Yıl: 2019 Cilt: 23 Sayı: 2 Sayfa Aralığı: 336 - 343 Metin Dili: İngilizce İndeks Tarihi: 27-05-2020

Biological activity and chemical composition of the essential oil of Nepeta cataria L

Öz:

In this study, chemical composition, antioxidant and antimicrobial activity of the essential oil of Nepeta cataria L., a native plant that grows in Lorestan region of Iran, were studied. Chemical constituents of the essential oil were identified by means of gas chromatography/mass spectrometry (GC/MS) and the relative content of each constituent was determined by area normalization. Disc diffusion and broth microdilution assays were used for in vitro antimicrobial screening. Antioxidant activity was employed by 2,2-diphenyl-1-picrylhydrazyl (DPPH) free-radical scavenging. The predominant bioactive ingredients with high percentage in N. Cataria essential oil was 4a-α, 7-α, 7a-βNepetalactone (53.87%). The essential oil’s IC50 value of 80.62 μg / mL in the DPPH assay, could be regarded as its strong antioxidant potential. The antibacterial activities of the essential oil were screened and compared against dozen important human pathogens. The essential oil showed good antibacterial activity, especially on Salmonella spp.. The biggest diameters of inhibition zones (29 mm) was recorded for Salmonella typhi and Salmonella paratyphi A showed the lowest MIC (160 μg / mL).

Anahtar Kelime:

Konular: Farmakoloji ve Eczacılık

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	ASHRAFI B, RAMAK P, EZATPOUR B, TALEI G (2019). Biological activity and chemical composition of the essential oil of Nepeta cataria L. , 336 - 343.
Chicago	ASHRAFI Behnam,RAMAK Parvin,EZATPOUR Behrouz,TALEI Gholam Reza Biological activity and chemical composition of the essential oil of Nepeta cataria L. (2019): 336 - 343.
MLA	ASHRAFI Behnam,RAMAK Parvin,EZATPOUR Behrouz,TALEI Gholam Reza Biological activity and chemical composition of the essential oil of Nepeta cataria L. , 2019, ss.336 - 343.
AMA	ASHRAFI B,RAMAK P,EZATPOUR B,TALEI G Biological activity and chemical composition of the essential oil of Nepeta cataria L. . 2019; 336 - 343.
Vancouver	ASHRAFI B,RAMAK P,EZATPOUR B,TALEI G Biological activity and chemical composition of the essential oil of Nepeta cataria L. . 2019; 336 - 343.
IEEE	ASHRAFI B,RAMAK P,EZATPOUR B,TALEI G "Biological activity and chemical composition of the essential oil of Nepeta cataria L." , ss.336 - 343, 2019.
ISNAD	ASHRAFI, Behnam vd. "Biological activity and chemical composition of the essential oil of Nepeta cataria L". (2019), 336-343.

APA	ASHRAFI B, RAMAK P, EZATPOUR B, TALEI G (2019). Biological activity and chemical composition of the essential oil of Nepeta cataria L. Journal of research in pharmacy (online), 23(2), 336 - 343.
Chicago	ASHRAFI Behnam,RAMAK Parvin,EZATPOUR Behrouz,TALEI Gholam Reza Biological activity and chemical composition of the essential oil of Nepeta cataria L. Journal of research in pharmacy (online) 23, no.2 (2019): 336 - 343.
MLA	ASHRAFI Behnam,RAMAK Parvin,EZATPOUR Behrouz,TALEI Gholam Reza Biological activity and chemical composition of the essential oil of Nepeta cataria L. Journal of research in pharmacy (online), vol.23, no.2, 2019, ss.336 - 343.
AMA	ASHRAFI B,RAMAK P,EZATPOUR B,TALEI G Biological activity and chemical composition of the essential oil of Nepeta cataria L. Journal of research in pharmacy (online). 2019; 23(2): 336 - 343.
Vancouver	ASHRAFI B,RAMAK P,EZATPOUR B,TALEI G Biological activity and chemical composition of the essential oil of Nepeta cataria L. Journal of research in pharmacy (online). 2019; 23(2): 336 - 343.
IEEE	ASHRAFI B,RAMAK P,EZATPOUR B,TALEI G "Biological activity and chemical composition of the essential oil of Nepeta cataria L." Journal of research in pharmacy (online), 23, ss.336 - 343, 2019.
ISNAD	ASHRAFI, Behnam vd. "Biological activity and chemical composition of the essential oil of Nepeta cataria L". Journal of research in pharmacy (online) 23/2 (2019), 336-343.