The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion
Yıl: 2019 Cilt: 47 Sayı: 1 Sayfa Aralığı: 21 - 28 Metin Dili: İngilizce DOI: 10.5543/tkda.2018.60497 İndeks Tarihi: 03-06-2020
The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion
Öz: Objective: Left ventricular (LV) hypertrophy predisposes themyocardium to ischemia through several mechanisms. TheLV mass index (LVMI) is used as a readily available and reliablemeasurement of LV hypertrophy. The LVMI can alsobe used to evaluate LV remodeling. The hypothesis of thisstudy was that LV hypertrophy might augment coronary collateralizationin patients with chronic total occlusion (CTO) andthe aim was to research any association between LVMI andcollateral formation in CTO. As a secondary goal, specific LVgeometric types that might be associated with collateral presencewere also investigated.Methods: A total of 305 patients with CTO were included andcategorized into 4 groups based on Rentrop grade.Results: The LVMI demonstrated an incremental linear trendas the Rentrop grade increased. In the receiver operatingcharacteristic curve, the likelihood that a cut-off value of 100.1g/m2 would accurately differentiate patients with collateralsfrom those without collaterals was 75.8%, with 68.5% sensitivityand 68.6% specificity. A 1 gram/m2 increase in LVMIwas associated with a 7.5% greater likelihood of collateral development.In addition, compared with normal geometry, thepresence of eccentric hypertrophy was associated with 6.7times higher odds of the presence of coronary collaterals.Conclusion: The results of this study indicated that a greaterLVMI predicted coronary collateral presence. Furthermore,having an eccentric geometric type of hypertrophy increasedthe likelihood of coronary collaterals more than other geometries.This finding signified that in addition to LV wall thickness,the type of hypertrophy was also decisive in predicting collateralpresence.
Anahtar Kelime: Kronik tam tıkanmalı hastalarda sol ventrikül kitle indeksi ile koroner kollateral dolaşımının ilişkisi
Öz: Amaç: Sol ventrikül hipertrofisi, çeşitli mekanizmalar aracılığıyla miyokardı iskemiye yatkınlaştırır. Sol ventrikül kitle indeksi (SVKİ), sol ventrikül hipertrofisinin kolayca elde edilebilen ve güvenilir bir ölçümü olarak kullanılmaktadır. Ayrıca, sol ventrikül yeniden şekillenmesi bu parametre ile kategorize edilebilir. Bu çalışmada, kronik tam tıkanmalı (KTO) hastalarda sol ventrikül hipertrofisinin koroner kollateralizasyonu artırabileceği hipotezinde bulunduk ve SVKİ ile KTO’daki kollateral gelişimi arasındaki ilişkiyi araştırmayı amaçladık. İkincil hedef olarak, hangi spesifik sol ventrikül geometrik tipinin kollateral varlığı ile ilişkili olabileceğini belirlemeyi amaçladık. Yöntemler: Kronik tam tıkanmalı saptanan 305 hastayı dahil ettik ve dört Rentrop Grade grubuna sınıflandırdık. Bulgular: Sol ventrikül kitle indeksi, artan Rentrop gruplarına doğru doğrusal bir artış gösterdi. ROC eğrisinde, SVKİ için 100.1 g/m2’lik bir kestirim değerinin, kollateralleri bulunan hastaları bulunmayanlardan %68.5 duyarlılık ve %68.6 özgüllük ile doğru bir şekilde ayırdetme ihtimali %75.8’di. SVKİ’nİn bir gram/m2’lik artışı, %7.5’lik artmış kollateral gelişme olasılığı ile ilişkiliydi. Normal geometriye kıyasla, eksantrik hipertrofi varlığı 6.7 kat daha fazla koroner kollateral varlığı ihtimali ile ilişkiliydi. Sonuç: Bu çalışmada KTO’lu hastalarda artmış SVKİ’nın koroner kollateral varlığnı öngördürdüğünü gösterdik. Ayrıca, geometrik tipte bir eksantrik hipertrofi geometrisine sahip olmak koroner kollateralleri diğer geometrilere göre daha fazla artırmaktadır. Bu bulgu, sol ventrikül duvar kalınlığının yanı sıra, hipertrofi tipinin de, kollateral varlığını öngörmede belirleyici olduğunu göstermektedir.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
- 1. Koerselman J, van der Graaf Y, de Jaegere PP, Grobbee DE. Coronary collaterals: an important and underexposed aspect of coronary artery disease. Circulation 2003;107:2507–11.
- 2. Werner GS. The role of coronary collaterals in chronic total occlusions. Curr Cardiol Rev 2014;10:57–64.
- 3. Zimarino M, D’Andreamatteo M, Waksman R, Epstein SE, De Caterina R. The dynamics of the coronary collateral circulation. Nat Rev Cardiol 2014;11:191–7.
- 4. Harrison DG, Barnes DH, Hiratzka LF, Eastham CL, Kerber RE, Marcus ML. The effect of cardiac hypertrophy on the coronary collateral circulation. Circulation 1985;71:1135–45.
- 5. Kyriakides ZS, Kremastinos DT, Michelakakis NA, Matsakas EP, Demovelis T, Toutouzas PK. Coronary collateral circulation in coronary artery disease and systemic hypertension. Am J Cardiol 1991;67:687–90.
- 6. Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L, et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr 2015;28:1–39.e14.
- 7. Sianos G, Morel M-A, Kappetein AP, Morice MC, Colombo A, Dawkins K, et al. The SYNTAX Score: an angiographic tool grading the complexity of coronary artery disease. EuroIntervention 2005;1:219–27.
- 8. Shah PB. Management of coronary chronic total occlusion. Circulation 2011;123:1780–4.
- 9. Rentrop KP, Cohen M, Blanke H, Phillips RA. Changes in collateral channel filling immediately after controlled coronary artery occlusion by an angioplasty balloon in human subjects. J Am Coll Cardiol 1985;5:587–92.
- 10. Zhang J, Yu KF. What’s the relative risk? A method of correcting the odds ratio in cohort studies of common outcomes. JAMA 1998;280:1690–1.
- 11. Karpanou EA, Vyssoulis GP, Skoumas JN, Zervopoulos GA, Moundaki VS, Toutouzas PK. Significance of arterial hypertension on coronary collateral circulation development and left ventricular function in coronary artery disease. J Hypertens Suppl 1988;6:S151–3.
- 12. Shu W, Jing J, Fu LC, Min JT, Bo YX, Ying Z, et al. The relationship between diastolic pressure and coronary collateral circulation in patients with stable angina pectoris and chronic total occlusion. Am J Hypertens 2013;26:630–5.
- 13. Cuspidi C, Sala C, Negri F, Mancia G, Morganti A; Italian Society of Hypertension. Prevalence of left-ventricular hypertrophy in hypertension: an updated review of echocardiographic studies. J Hum Hypertens 2012;26:343–9.
- 14. Stanton T, Dunn FG. Hypertension, Left Ventricular Hypertrophy, and Myocardial Ischemia. Med Clin North Am 2017;101:29–41.
- 15. Lazzeroni D, Rimoldi O, Camici PG. From Left Ventricular Hypertrophy to Dysfunction and Failure. Circ J 2016;80:555– 64.
| APA | ÇETİN M, Özcan çetin E, OCAK K, Ozcan Celebi O, Aras D, Temizhan A, AYDOĞDU S (2019). The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion. , 21 - 28. 10.5543/tkda.2018.60497 |
| Chicago | ÇETİN Mehmet Serkan,Özcan çetin Elif hande,OCAK Kadir,Ozcan Celebi Ozlem,Aras Dursun,Temizhan Ahmet,AYDOĞDU Sinan The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion. (2019): 21 - 28. 10.5543/tkda.2018.60497 |
| MLA | ÇETİN Mehmet Serkan,Özcan çetin Elif hande,OCAK Kadir,Ozcan Celebi Ozlem,Aras Dursun,Temizhan Ahmet,AYDOĞDU Sinan The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion. , 2019, ss.21 - 28. 10.5543/tkda.2018.60497 |
| AMA | ÇETİN M,Özcan çetin E,OCAK K,Ozcan Celebi O,Aras D,Temizhan A,AYDOĞDU S The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion. . 2019; 21 - 28. 10.5543/tkda.2018.60497 |
| Vancouver | ÇETİN M,Özcan çetin E,OCAK K,Ozcan Celebi O,Aras D,Temizhan A,AYDOĞDU S The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion. . 2019; 21 - 28. 10.5543/tkda.2018.60497 |
| IEEE | ÇETİN M,Özcan çetin E,OCAK K,Ozcan Celebi O,Aras D,Temizhan A,AYDOĞDU S "The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion." , ss.21 - 28, 2019. 10.5543/tkda.2018.60497 |
| ISNAD | ÇETİN, Mehmet Serkan vd. "The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion". (2019), 21-28. https://doi.org/10.5543/tkda.2018.60497 |
| APA | ÇETİN M, Özcan çetin E, OCAK K, Ozcan Celebi O, Aras D, Temizhan A, AYDOĞDU S (2019). The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion. Türk Kardiyoloji Derneği Arşivi, 47(1), 21 - 28. 10.5543/tkda.2018.60497 |
| Chicago | ÇETİN Mehmet Serkan,Özcan çetin Elif hande,OCAK Kadir,Ozcan Celebi Ozlem,Aras Dursun,Temizhan Ahmet,AYDOĞDU Sinan The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion. Türk Kardiyoloji Derneği Arşivi 47, no.1 (2019): 21 - 28. 10.5543/tkda.2018.60497 |
| MLA | ÇETİN Mehmet Serkan,Özcan çetin Elif hande,OCAK Kadir,Ozcan Celebi Ozlem,Aras Dursun,Temizhan Ahmet,AYDOĞDU Sinan The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion. Türk Kardiyoloji Derneği Arşivi, vol.47, no.1, 2019, ss.21 - 28. 10.5543/tkda.2018.60497 |
| AMA | ÇETİN M,Özcan çetin E,OCAK K,Ozcan Celebi O,Aras D,Temizhan A,AYDOĞDU S The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion. Türk Kardiyoloji Derneği Arşivi. 2019; 47(1): 21 - 28. 10.5543/tkda.2018.60497 |
| Vancouver | ÇETİN M,Özcan çetin E,OCAK K,Ozcan Celebi O,Aras D,Temizhan A,AYDOĞDU S The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion. Türk Kardiyoloji Derneği Arşivi. 2019; 47(1): 21 - 28. 10.5543/tkda.2018.60497 |
| IEEE | ÇETİN M,Özcan çetin E,OCAK K,Ozcan Celebi O,Aras D,Temizhan A,AYDOĞDU S "The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion." Türk Kardiyoloji Derneği Arşivi, 47, ss.21 - 28, 2019. 10.5543/tkda.2018.60497 |
| ISNAD | ÇETİN, Mehmet Serkan vd. "The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion". Türk Kardiyoloji Derneği Arşivi 47/1 (2019), 21-28. https://doi.org/10.5543/tkda.2018.60497 |
