Yıl: 2019 Cilt: 47 Sayı: 1 Sayfa Aralığı: 21 - 28 Metin Dili: İngilizce DOI: 10.5543/tkda.2018.60497 İndeks Tarihi: 03-06-2020

The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion

Öz:
Objective: Left ventricular (LV) hypertrophy predisposes themyocardium to ischemia through several mechanisms. TheLV mass index (LVMI) is used as a readily available and reliablemeasurement of LV hypertrophy. The LVMI can alsobe used to evaluate LV remodeling. The hypothesis of thisstudy was that LV hypertrophy might augment coronary collateralizationin patients with chronic total occlusion (CTO) andthe aim was to research any association between LVMI andcollateral formation in CTO. As a secondary goal, specific LVgeometric types that might be associated with collateral presencewere also investigated.Methods: A total of 305 patients with CTO were included andcategorized into 4 groups based on Rentrop grade.Results: The LVMI demonstrated an incremental linear trendas the Rentrop grade increased. In the receiver operatingcharacteristic curve, the likelihood that a cut-off value of 100.1g/m2 would accurately differentiate patients with collateralsfrom those without collaterals was 75.8%, with 68.5% sensitivityand 68.6% specificity. A 1 gram/m2 increase in LVMIwas associated with a 7.5% greater likelihood of collateral development.In addition, compared with normal geometry, thepresence of eccentric hypertrophy was associated with 6.7times higher odds of the presence of coronary collaterals.Conclusion: The results of this study indicated that a greaterLVMI predicted coronary collateral presence. Furthermore,having an eccentric geometric type of hypertrophy increasedthe likelihood of coronary collaterals more than other geometries.This finding signified that in addition to LV wall thickness,the type of hypertrophy was also decisive in predicting collateralpresence.
Anahtar Kelime:

Kronik tam tıkanmalı hastalarda sol ventrikül kitle indeksi ile koroner kollateral dolaşımının ilişkisi

Öz:
Amaç: Sol ventrikül hipertrofisi, çeşitli mekanizmalar aracılığıyla miyokardı iskemiye yatkınlaştırır. Sol ventrikül kitle indeksi (SVKİ), sol ventrikül hipertrofisinin kolayca elde edilebilen ve güvenilir bir ölçümü olarak kullanılmaktadır. Ayrıca, sol ventrikül yeniden şekillenmesi bu parametre ile kategorize edilebilir. Bu çalışmada, kronik tam tıkanmalı (KTO) hastalarda sol ventrikül hipertrofisinin koroner kollateralizasyonu artırabileceği hipotezinde bulunduk ve SVKİ ile KTO’daki kollateral gelişimi arasındaki ilişkiyi araştırmayı amaçladık. İkincil hedef olarak, hangi spesifik sol ventrikül geometrik tipinin kollateral varlığı ile ilişkili olabileceğini belirlemeyi amaçladık. Yöntemler: Kronik tam tıkanmalı saptanan 305 hastayı dahil ettik ve dört Rentrop Grade grubuna sınıflandırdık. Bulgular: Sol ventrikül kitle indeksi, artan Rentrop gruplarına doğru doğrusal bir artış gösterdi. ROC eğrisinde, SVKİ için 100.1 g/m2’lik bir kestirim değerinin, kollateralleri bulunan hastaları bulunmayanlardan %68.5 duyarlılık ve %68.6 özgüllük ile doğru bir şekilde ayırdetme ihtimali %75.8’di. SVKİ’nİn bir gram/m2’lik artışı, %7.5’lik artmış kollateral gelişme olasılığı ile ilişkiliydi. Normal geometriye kıyasla, eksantrik hipertrofi varlığı 6.7 kat daha fazla koroner kollateral varlığı ihtimali ile ilişkiliydi. Sonuç: Bu çalışmada KTO’lu hastalarda artmış SVKİ’nın koroner kollateral varlığnı öngördürdüğünü gösterdik. Ayrıca, geometrik tipte bir eksantrik hipertrofi geometrisine sahip olmak koroner kollateralleri diğer geometrilere göre daha fazla artırmaktadır. Bu bulgu, sol ventrikül duvar kalınlığının yanı sıra, hipertrofi tipinin de, kollateral varlığını öngörmede belirleyici olduğunu göstermektedir.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA ÇETİN M, Özcan çetin E, OCAK K, Ozcan Celebi O, Aras D, Temizhan A, AYDOĞDU S (2019). The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion. , 21 - 28. 10.5543/tkda.2018.60497
Chicago ÇETİN Mehmet Serkan,Özcan çetin Elif hande,OCAK Kadir,Ozcan Celebi Ozlem,Aras Dursun,Temizhan Ahmet,AYDOĞDU Sinan The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion. (2019): 21 - 28. 10.5543/tkda.2018.60497
MLA ÇETİN Mehmet Serkan,Özcan çetin Elif hande,OCAK Kadir,Ozcan Celebi Ozlem,Aras Dursun,Temizhan Ahmet,AYDOĞDU Sinan The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion. , 2019, ss.21 - 28. 10.5543/tkda.2018.60497
AMA ÇETİN M,Özcan çetin E,OCAK K,Ozcan Celebi O,Aras D,Temizhan A,AYDOĞDU S The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion. . 2019; 21 - 28. 10.5543/tkda.2018.60497
Vancouver ÇETİN M,Özcan çetin E,OCAK K,Ozcan Celebi O,Aras D,Temizhan A,AYDOĞDU S The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion. . 2019; 21 - 28. 10.5543/tkda.2018.60497
IEEE ÇETİN M,Özcan çetin E,OCAK K,Ozcan Celebi O,Aras D,Temizhan A,AYDOĞDU S "The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion." , ss.21 - 28, 2019. 10.5543/tkda.2018.60497
ISNAD ÇETİN, Mehmet Serkan vd. "The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion". (2019), 21-28. https://doi.org/10.5543/tkda.2018.60497
APA ÇETİN M, Özcan çetin E, OCAK K, Ozcan Celebi O, Aras D, Temizhan A, AYDOĞDU S (2019). The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion. Türk Kardiyoloji Derneği Arşivi, 47(1), 21 - 28. 10.5543/tkda.2018.60497
Chicago ÇETİN Mehmet Serkan,Özcan çetin Elif hande,OCAK Kadir,Ozcan Celebi Ozlem,Aras Dursun,Temizhan Ahmet,AYDOĞDU Sinan The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion. Türk Kardiyoloji Derneği Arşivi 47, no.1 (2019): 21 - 28. 10.5543/tkda.2018.60497
MLA ÇETİN Mehmet Serkan,Özcan çetin Elif hande,OCAK Kadir,Ozcan Celebi Ozlem,Aras Dursun,Temizhan Ahmet,AYDOĞDU Sinan The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion. Türk Kardiyoloji Derneği Arşivi, vol.47, no.1, 2019, ss.21 - 28. 10.5543/tkda.2018.60497
AMA ÇETİN M,Özcan çetin E,OCAK K,Ozcan Celebi O,Aras D,Temizhan A,AYDOĞDU S The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion. Türk Kardiyoloji Derneği Arşivi. 2019; 47(1): 21 - 28. 10.5543/tkda.2018.60497
Vancouver ÇETİN M,Özcan çetin E,OCAK K,Ozcan Celebi O,Aras D,Temizhan A,AYDOĞDU S The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion. Türk Kardiyoloji Derneği Arşivi. 2019; 47(1): 21 - 28. 10.5543/tkda.2018.60497
IEEE ÇETİN M,Özcan çetin E,OCAK K,Ozcan Celebi O,Aras D,Temizhan A,AYDOĞDU S "The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion." Türk Kardiyoloji Derneği Arşivi, 47, ss.21 - 28, 2019. 10.5543/tkda.2018.60497
ISNAD ÇETİN, Mehmet Serkan vd. "The association between left ventricular mass index and coronary collateral circulation in patients with chronic total occlusion". Türk Kardiyoloji Derneği Arşivi 47/1 (2019), 21-28. https://doi.org/10.5543/tkda.2018.60497