Evaluation of enzyme inhibitory and antioxidant activity of some Lamiaceae plants
Yıl: 2019 Cilt: 23 Sayı: 4 Sayfa Aralığı: 749 - 758 Metin Dili: İngilizce DOI: 10.12991/jrp.2019.184 İndeks Tarihi: 05-06-2020
Evaluation of enzyme inhibitory and antioxidant activity of some Lamiaceae plants
Öz: Lamiaceae is one of the most widespread families in Turkey. The aim of this study was to determine antialzheimer, antidiabetic, antioxidant and antiobesity activities of ethanol extracts of Lamium purpureum var. purpureum, Origanum onites, Salvia sclarea, S. virgata and Thymus zygioides var. lycaonius. Acetylcholinesterase, butyrylcholinesterase, α-amylase, α-glucosidase, and pancreatic lipase inhibitory activities were tested for the determination of the activity of these extracts. Furthermore, total antioxidant, ferric-reducing antioxidant power, metalchelating and N,N-dimethyl-p-phenylendiamine radical scavenging assays were utilized to screen antioxidant activity. Total phenolic content of the extracts were also calculated. Among the tested extracts, T. zygioides var. lycaonius aerial part extract (85.28 ± 0.89 %) showed the highest inhibitory activity against α-glucosidase. The inhibitory activities of all extracts against α-amylase were lower than 50 %. S. sclarea leaf extract indicated remarkable butyrylcholinesterase inhibition (51.76 ± 1.04 %), but all of the plant extracts were inactive against acetylcholinesterase. The Salvia species showed the highest total antioxidant activity. S. sclarea flower (1.34 ± 0.08) and leaf (1.34 ± 0.08) extracts showed the highest ferric-reducing antioxidant power activities. Our findings indicated that O. onites, S. sclarea, S. virgata, and T. zygioides var. lycaonius extracts showed valuable inhibitory activity and emerged as the sources of possible α-glucosidase inhibitors for future studies
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| APA | Gök H, DELİORMAN ORHAN D, ERDOĞAN ORHAN İ, ORHAN N, Aslan M (2019). Evaluation of enzyme inhibitory and antioxidant activity of some Lamiaceae plants. , 749 - 758. 10.12991/jrp.2019.184 |
| Chicago | Gök Hasya Nazlı,DELİORMAN ORHAN Didem,ERDOĞAN ORHAN İLKAY,ORHAN Nilüfer,Aslan Mustafa Evaluation of enzyme inhibitory and antioxidant activity of some Lamiaceae plants. (2019): 749 - 758. 10.12991/jrp.2019.184 |
| MLA | Gök Hasya Nazlı,DELİORMAN ORHAN Didem,ERDOĞAN ORHAN İLKAY,ORHAN Nilüfer,Aslan Mustafa Evaluation of enzyme inhibitory and antioxidant activity of some Lamiaceae plants. , 2019, ss.749 - 758. 10.12991/jrp.2019.184 |
| AMA | Gök H,DELİORMAN ORHAN D,ERDOĞAN ORHAN İ,ORHAN N,Aslan M Evaluation of enzyme inhibitory and antioxidant activity of some Lamiaceae plants. . 2019; 749 - 758. 10.12991/jrp.2019.184 |
| Vancouver | Gök H,DELİORMAN ORHAN D,ERDOĞAN ORHAN İ,ORHAN N,Aslan M Evaluation of enzyme inhibitory and antioxidant activity of some Lamiaceae plants. . 2019; 749 - 758. 10.12991/jrp.2019.184 |
| IEEE | Gök H,DELİORMAN ORHAN D,ERDOĞAN ORHAN İ,ORHAN N,Aslan M "Evaluation of enzyme inhibitory and antioxidant activity of some Lamiaceae plants." , ss.749 - 758, 2019. 10.12991/jrp.2019.184 |
| ISNAD | Gök, Hasya Nazlı vd. "Evaluation of enzyme inhibitory and antioxidant activity of some Lamiaceae plants". (2019), 749-758. https://doi.org/10.12991/jrp.2019.184 |
| APA | Gök H, DELİORMAN ORHAN D, ERDOĞAN ORHAN İ, ORHAN N, Aslan M (2019). Evaluation of enzyme inhibitory and antioxidant activity of some Lamiaceae plants. Journal of research in pharmacy (online), 23(4), 749 - 758. 10.12991/jrp.2019.184 |
| Chicago | Gök Hasya Nazlı,DELİORMAN ORHAN Didem,ERDOĞAN ORHAN İLKAY,ORHAN Nilüfer,Aslan Mustafa Evaluation of enzyme inhibitory and antioxidant activity of some Lamiaceae plants. Journal of research in pharmacy (online) 23, no.4 (2019): 749 - 758. 10.12991/jrp.2019.184 |
| MLA | Gök Hasya Nazlı,DELİORMAN ORHAN Didem,ERDOĞAN ORHAN İLKAY,ORHAN Nilüfer,Aslan Mustafa Evaluation of enzyme inhibitory and antioxidant activity of some Lamiaceae plants. Journal of research in pharmacy (online), vol.23, no.4, 2019, ss.749 - 758. 10.12991/jrp.2019.184 |
| AMA | Gök H,DELİORMAN ORHAN D,ERDOĞAN ORHAN İ,ORHAN N,Aslan M Evaluation of enzyme inhibitory and antioxidant activity of some Lamiaceae plants. Journal of research in pharmacy (online). 2019; 23(4): 749 - 758. 10.12991/jrp.2019.184 |
| Vancouver | Gök H,DELİORMAN ORHAN D,ERDOĞAN ORHAN İ,ORHAN N,Aslan M Evaluation of enzyme inhibitory and antioxidant activity of some Lamiaceae plants. Journal of research in pharmacy (online). 2019; 23(4): 749 - 758. 10.12991/jrp.2019.184 |
| IEEE | Gök H,DELİORMAN ORHAN D,ERDOĞAN ORHAN İ,ORHAN N,Aslan M "Evaluation of enzyme inhibitory and antioxidant activity of some Lamiaceae plants." Journal of research in pharmacy (online), 23, ss.749 - 758, 2019. 10.12991/jrp.2019.184 |
| ISNAD | Gök, Hasya Nazlı vd. "Evaluation of enzyme inhibitory and antioxidant activity of some Lamiaceae plants". Journal of research in pharmacy (online) 23/4 (2019), 749-758. https://doi.org/10.12991/jrp.2019.184 |
