Admission neutrophil-to-lymphocyte ratio and postoperative mortality in elderly patients with hip fracture
Yıl: 2019 Cilt: 25 Sayı: 1 Sayfa Aralığı: 71 - 74 Metin Dili: İngilizce DOI: 10.5505/tjtes.2018.94572 İndeks Tarihi: 10-06-2020
Admission neutrophil-to-lymphocyte ratio and postoperative mortality in elderly patients with hip fracture
Öz: BACKGROUND: Hip fractures in elderly patients are associated with a high mortality rate. Most deaths associated with hip fractureresult from complications after surgery. Recent studies suggest that the neutrophil-to-lymphocyte ratio (NLR), which is a laboratorymarker used to evaluate systemic inflammation, may be useful to estimate excess mortality. This study aimed to investigate the prognostic value of admission NLR in elderly patients with hip fracture.METHODS: We evaluated patients admitted to the Orthopaedic Surgery Department of Balikesir-Edremit State Hospital. Inclusioncriteria were female gender, age between 65 and 80 years, ASA score of 3, unstable intertrochanteric fracture treated with hemiarthroplasty, and time between fracture and surgery less than 72 h. Patients with multiple fracture, previous same side or other sidehip surgery, pathological fracture, such as fracture caused by tumor or metabolic bone disease (e.g., Paget’s disease), and malignancieswere excluded from this study (purposive sampling technique). Finally, “case” (group 1) was defined as patients who died within 1 yearafter surgery, whereas “control” (group 2) was defined as patients who survived. Patients in group 1 and 2 were statistically comparedin terms of NLR value on hospital admission. A total of 22 patients (44%) were included in group 1, and 28 (56%) were included ingroup 2.RESULTS: We found that the admission NLR values of patients in the mortality group were significantly higher than those of patientsin the control group (p<0.001). The cutoff value of NLR was calculated as 4.7 on ROC analysis.CONCLUSION: We believe that the NLR value at admission could be used for risk stratification of mortality in elderly patientswith hip fracture.
Anahtar Kelime: Kalça kırıklı yaşlı hastalarda nötrofil-lenfosit oranı ve ameliyat sonrası mortalite
Öz: AMAÇ: Kalça kırıklı yaşlı hastalarda ameliyat sonrası mortalitenin yüksek olduğu bildirilmiştir. Bunun nedeni genellikle ameliyat sonrası gelişen komplikasyonlardır. Güncel çalışmalarda nötrofil-lenfosit oranının (NLR), yüksek mortalite oranı ile ilişkili olduğu belirtilmektedir. Çalışmamızda amaç, kalça kırıklı yaşlı hastalarda, hastaneye yatış esnasındaki NLR’nin, ameliyat sonrası mortalite ile ilişkisi olup olmadığını araştırmak idi. GEREÇ VE YÖNTEM: Balıkesir Edremit Devlet Hastanesi Ortopedi ve Travmatoloji Kliniği’nde 65–80 yaş arası, ASA puanı 3 olan, stabil olmayan trokanterik kırık nedeniyle çimentolu bipolar kalça protezi uygulanan kadın hastalar çalışmaya dahil edildi. Tüm hastalar kırık sonrası ilk 72 saat içinde ameliyat edilmiş idi (amaca yönelik örnekleme tekniği). Grup 1 hastalar ameliyat sonrası birinci yıl içinde ölenler (n=22, %44), grup 2 hastalar (n=28, %56) ise yaşayanlar idi. Her iki grup ameliyat öncesi NLR değerleri açısından istatistiksel olarak karşılaştırıldı. BULGULAR: Gruplar arasında ameliyat öncesi NLR değeri açısından anlamlı fark tespit edildi (p<0.001). ROC analizinde kesim değeri 4.7 bulundu. TARTIŞMA: Buna göre ameliyat öncesi NLR değerinin kalça kırıklı yaşlı hastalarda mortalite ile ilişkili olduğu kanaatindeyiz.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | TEMİZ A, ERSÖZLÜ S (2019). Admission neutrophil-to-lymphocyte ratio and postoperative mortality in elderly patients with hip fracture. , 71 - 74. 10.5505/tjtes.2018.94572 |
| Chicago | TEMİZ Aytun,ERSÖZLÜ Salim Admission neutrophil-to-lymphocyte ratio and postoperative mortality in elderly patients with hip fracture. (2019): 71 - 74. 10.5505/tjtes.2018.94572 |
| MLA | TEMİZ Aytun,ERSÖZLÜ Salim Admission neutrophil-to-lymphocyte ratio and postoperative mortality in elderly patients with hip fracture. , 2019, ss.71 - 74. 10.5505/tjtes.2018.94572 |
| AMA | TEMİZ A,ERSÖZLÜ S Admission neutrophil-to-lymphocyte ratio and postoperative mortality in elderly patients with hip fracture. . 2019; 71 - 74. 10.5505/tjtes.2018.94572 |
| Vancouver | TEMİZ A,ERSÖZLÜ S Admission neutrophil-to-lymphocyte ratio and postoperative mortality in elderly patients with hip fracture. . 2019; 71 - 74. 10.5505/tjtes.2018.94572 |
| IEEE | TEMİZ A,ERSÖZLÜ S "Admission neutrophil-to-lymphocyte ratio and postoperative mortality in elderly patients with hip fracture." , ss.71 - 74, 2019. 10.5505/tjtes.2018.94572 |
| ISNAD | TEMİZ, Aytun - ERSÖZLÜ, Salim. "Admission neutrophil-to-lymphocyte ratio and postoperative mortality in elderly patients with hip fracture". (2019), 71-74. https://doi.org/10.5505/tjtes.2018.94572 |
| APA | TEMİZ A, ERSÖZLÜ S (2019). Admission neutrophil-to-lymphocyte ratio and postoperative mortality in elderly patients with hip fracture. Ulusal Travma ve Acil Cerrahi Dergisi, 25(1), 71 - 74. 10.5505/tjtes.2018.94572 |
| Chicago | TEMİZ Aytun,ERSÖZLÜ Salim Admission neutrophil-to-lymphocyte ratio and postoperative mortality in elderly patients with hip fracture. Ulusal Travma ve Acil Cerrahi Dergisi 25, no.1 (2019): 71 - 74. 10.5505/tjtes.2018.94572 |
| MLA | TEMİZ Aytun,ERSÖZLÜ Salim Admission neutrophil-to-lymphocyte ratio and postoperative mortality in elderly patients with hip fracture. Ulusal Travma ve Acil Cerrahi Dergisi, vol.25, no.1, 2019, ss.71 - 74. 10.5505/tjtes.2018.94572 |
| AMA | TEMİZ A,ERSÖZLÜ S Admission neutrophil-to-lymphocyte ratio and postoperative mortality in elderly patients with hip fracture. Ulusal Travma ve Acil Cerrahi Dergisi. 2019; 25(1): 71 - 74. 10.5505/tjtes.2018.94572 |
| Vancouver | TEMİZ A,ERSÖZLÜ S Admission neutrophil-to-lymphocyte ratio and postoperative mortality in elderly patients with hip fracture. Ulusal Travma ve Acil Cerrahi Dergisi. 2019; 25(1): 71 - 74. 10.5505/tjtes.2018.94572 |
| IEEE | TEMİZ A,ERSÖZLÜ S "Admission neutrophil-to-lymphocyte ratio and postoperative mortality in elderly patients with hip fracture." Ulusal Travma ve Acil Cerrahi Dergisi, 25, ss.71 - 74, 2019. 10.5505/tjtes.2018.94572 |
| ISNAD | TEMİZ, Aytun - ERSÖZLÜ, Salim. "Admission neutrophil-to-lymphocyte ratio and postoperative mortality in elderly patients with hip fracture". Ulusal Travma ve Acil Cerrahi Dergisi 25/1 (2019), 71-74. https://doi.org/10.5505/tjtes.2018.94572 |
