Role of increased immature granulocyte percentage in the early prediction of acute necrotizing pancreatitis
Yıl: 2019 Cilt: 25 Sayı: 2 Sayfa Aralığı: 177 - 182 Metin Dili: İngilizce DOI: 10.5505/tjtes.2019.70679 İndeks Tarihi: 10-06-2020
Role of increased immature granulocyte percentage in the early prediction of acute necrotizing pancreatitis
Öz: BACKGROUND: Acute necrotizing pancreatitis (ANP) is the most severe form of acute pancreatitis (AP), and it has high mortalityrates. Therefore, early diagnosis and treatment are of critical importance for the prognosis. The aim of this study was to investigatethe effectiveness of immature granulocyte percentage (IG%) in the early prediction of ANP.METHODS: This retrospective study included 96 adult patients hospitalized with a diagnosis of AP. Demographic data of the patientswere recorded. The white blood cell (WBC) count, neutrophil-to-lymphocyte ratio (NLR), IG%, C-reactive protein (CRP), and amylase levels were determined. Furthermore, computed abdominal tomography was applied to the patients, and the length of hospitalstay was recorded. Patients were divided into two groups as those with acute edematous pancreatitis and ANP, according to thetomography results. The differences between the groups were analyzed statistically.RESULTS: The WBC count, NLR, CRP, and IG% were significant markers in the prediction of ANP. However, IG% had higher valueswith regard to the sensitivity, specificity, AUROC , and negative and positive predictive values (100%, 95%, 0.982, 78.9%, and 100%,respectively).CONCLUSION: An increased IG% is a simple, fast, and effective marker in the early prediction of ANP.
Anahtar Kelime: Akut nekrotizan pankreatitin erken tahmininde artmış immatür granülosit yüzdesinin rolü
Öz: AMAÇ: Akut nekrotizan pankreatit akut pankreatitin en şiddetli formudur ve yüksek mortalite oranlarına sahiptir. Bu yüzden bu hastalıkta erken tanı ve tedavi prognoz açısından kritik önem taşımaktadır. Bu çalışmanın amacı immatür granülosit yüzdesinin (IG%), akut nekrotizan pankreatitin erken tahminindeki etkinliğini araştırmaktır. GEREÇ VE YÖNTEM: Bu geriye dönük çalışma akut pankreatit tanısıyla hastaneye yatırılan 96 erişkin hasta üzerinde gerçekleştirildi. Hastaların demografik verileri kaydedildi. Beyaz küre sayısı, nötrofil/lenfosit oranı, IG%, C-reaktif protein ve amilaz düzeyleri tespit edildi. Ayrıca hastalara kontrastlı bilgisayarlı abdominal tomografi incelemesi yapıldı ve hastanede kalış süreleri kaydedildi. Hastalar tomografi sonuçlarına göre akut ödematöz pankreatit ve akut nekrotizan pankreatit olarak iki gruba ayrıldı. Gruplar arasındaki farklılıklar istatistiksel olarak analiz edildi. BULGULAR: Beyaz küre sayısı, nötrofil/lenfosit oranı, C-rektif protein ve IG% akut nekrotizan pankreatit tahmininde anlamlı belirteçlerdi. Ancak IG%’nin duyarlılık, özgüllük, AUROC, negatif ve pozitif tahmin edici değerleri diğerlerinden daha yüksek idi (sırasıyla, %100, %95, 0.982, %78.9, %100). TARTIŞMA: Artmış IG% akut nekrotizan pankreatitin erken tahmininde basit, hızlı ve etkili bir belirteçtir.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Ünal Y, BARLAS A (2019). Role of increased immature granulocyte percentage in the early prediction of acute necrotizing pancreatitis. , 177 - 182. 10.5505/tjtes.2019.70679 |
| Chicago | Ünal Yılmaz,BARLAS AZIZ MUTLU Role of increased immature granulocyte percentage in the early prediction of acute necrotizing pancreatitis. (2019): 177 - 182. 10.5505/tjtes.2019.70679 |
| MLA | Ünal Yılmaz,BARLAS AZIZ MUTLU Role of increased immature granulocyte percentage in the early prediction of acute necrotizing pancreatitis. , 2019, ss.177 - 182. 10.5505/tjtes.2019.70679 |
| AMA | Ünal Y,BARLAS A Role of increased immature granulocyte percentage in the early prediction of acute necrotizing pancreatitis. . 2019; 177 - 182. 10.5505/tjtes.2019.70679 |
| Vancouver | Ünal Y,BARLAS A Role of increased immature granulocyte percentage in the early prediction of acute necrotizing pancreatitis. . 2019; 177 - 182. 10.5505/tjtes.2019.70679 |
| IEEE | Ünal Y,BARLAS A "Role of increased immature granulocyte percentage in the early prediction of acute necrotizing pancreatitis." , ss.177 - 182, 2019. 10.5505/tjtes.2019.70679 |
| ISNAD | Ünal, Yılmaz - BARLAS, AZIZ MUTLU. "Role of increased immature granulocyte percentage in the early prediction of acute necrotizing pancreatitis". (2019), 177-182. https://doi.org/10.5505/tjtes.2019.70679 |
| APA | Ünal Y, BARLAS A (2019). Role of increased immature granulocyte percentage in the early prediction of acute necrotizing pancreatitis. Ulusal Travma ve Acil Cerrahi Dergisi, 25(2), 177 - 182. 10.5505/tjtes.2019.70679 |
| Chicago | Ünal Yılmaz,BARLAS AZIZ MUTLU Role of increased immature granulocyte percentage in the early prediction of acute necrotizing pancreatitis. Ulusal Travma ve Acil Cerrahi Dergisi 25, no.2 (2019): 177 - 182. 10.5505/tjtes.2019.70679 |
| MLA | Ünal Yılmaz,BARLAS AZIZ MUTLU Role of increased immature granulocyte percentage in the early prediction of acute necrotizing pancreatitis. Ulusal Travma ve Acil Cerrahi Dergisi, vol.25, no.2, 2019, ss.177 - 182. 10.5505/tjtes.2019.70679 |
| AMA | Ünal Y,BARLAS A Role of increased immature granulocyte percentage in the early prediction of acute necrotizing pancreatitis. Ulusal Travma ve Acil Cerrahi Dergisi. 2019; 25(2): 177 - 182. 10.5505/tjtes.2019.70679 |
| Vancouver | Ünal Y,BARLAS A Role of increased immature granulocyte percentage in the early prediction of acute necrotizing pancreatitis. Ulusal Travma ve Acil Cerrahi Dergisi. 2019; 25(2): 177 - 182. 10.5505/tjtes.2019.70679 |
| IEEE | Ünal Y,BARLAS A "Role of increased immature granulocyte percentage in the early prediction of acute necrotizing pancreatitis." Ulusal Travma ve Acil Cerrahi Dergisi, 25, ss.177 - 182, 2019. 10.5505/tjtes.2019.70679 |
| ISNAD | Ünal, Yılmaz - BARLAS, AZIZ MUTLU. "Role of increased immature granulocyte percentage in the early prediction of acute necrotizing pancreatitis". Ulusal Travma ve Acil Cerrahi Dergisi 25/2 (2019), 177-182. https://doi.org/10.5505/tjtes.2019.70679 |
