TY  - JOUR
TI  - Saliva profiles in children with congenital heart disease
AB  - The low salivary pH and buffering capacity are caused by using heart failuremedications. For this reason oral health should be supported in cardiac patients,it is necessary that they attend dental clinics for regular follow up. The aim of thisstudy is to evaluate the relationship between the salivary oxidative stress markersand salivary pH, salivary buffering capacity, salivary flow rate and dental caries ofchildren with congenital heart disease (CHD).Material and MethodsThis cross sectional study was carried out with 42 CHD and 42 healthy children. Theparticipants’ gender, age, general health and medications, and caries scores (dfs/DMFS) were written down, then their unstimulated saliva samples were collected.These specimens were evaluated in terms of the salivary secretion rate, salivarybuffering capacity, pH, protein levels, superoxide dismutase (SOD), ferric reducingantioxidant power (FRAP), the thiobarbituric acid reactive substances (TBARS),protein carbonyl, protein thiols, total sialic acid.ResultsBoth groups showed caries at similar levels. The salivary pH and buffering capacitywere significantly less in the children with CHD than in the controls. The levels ofTBARS and protein carbonyl were significantly higher in the children with CHDthan in the controls. There was not any significant difference relating to the meansalivary secretion rate, protein levels, SOD, FRAP, protein thiols and total sialic acid.ConclusionThe elevated TBARS and protein carbonyl levels in the patients with CHD wereobserved as an indicator of the free radical damage leading to oxidative stress.
AU  - Bayram, Merve
AU  - USLU, Ezel
AU  - GÜVEN, Yegane
AU  - Seymen, Figen
AU  - KORUYUCU, Mine
AU  - Batu, Sule
DO  - 10.26650/eor.20200087
PY  - 2020
JO  - European oral research (Online)
VL  - 54
IS  - 1
SN  - 2630-6158
SP  - 48
EP  - 54
DB  - TRDizin
UR  - http://search/yayin/detay/347586
ER  -