The purpose of this study is to examine the profitability of hotel companies traded on capital markets in European continent by using DuPont financial analysis technique. Besides, variables were tried to be determined that affect the return on asset and return on equity of the hotel companies in the context of variables used in the DuPont analysis technique. For these purposes , the ratios used to determine return on asset and return on equity in the DuPont technique were analyzed of the 76 hotel companies, whose shares traded on stock exchange in European continent, 2007-2016 period by panel data method. According to the results obtained in the study, the effect of net profit margin on the return on asset is positive and significant but the effect of asset turnover is not significant on return on asset of the publicly traded hotel companies in Europe. On the other hand, the effect of net profit margin on return on equity is significant and positive, and the effect of equity multiplier is significant and negative of the publicly traded hotel companies in Europe. It has been determined that the asset turnover does not have any significant effect on retu rn on equity, as in return on asset. As a result of the study, it was determined that publicly traded hotel companies in Europe could not earn income and profits to meet expenses and costs in the examined period.