Effectiveness of bitter melon extract in the treatment of ischemic wounds in rats
Yıl: 2018 Cilt: 42 Sayı: 6 Sayfa Aralığı: 506 - 516 Metin Dili: İngilizce DOI: 10.3906/biy-1804-36 İndeks Tarihi: 09-07-2020
Effectiveness of bitter melon extract in the treatment of ischemic wounds in rats
Öz: There is no consensus on the properties of an ideal dressing for treating wounds. The aim of this study was to investigatethe efficacy of dressings using topically administered bitter melon extract with olive oil, pure olive oil, nitrofurazone, and saline in thehealing of ischemic wounds. A sample group of 48 rats was used in the trial. Their wounds were treated with bitter melon extract, pureolive oil, nitrofurazone, and saline. Data were collected between October 2014 and April 2015. The highest percentage (94.7%) of woundhealing was observed in the bitter melon extract group and the lowest percentage (86.3%) in the nitrofurazone group. At the end of the21st day, macroscopic reepithelialization was observed in 9 wounds in the bitter melon extract group (75%), in 6 wounds in the pureolive oil group (50%), and in only 3 wounds in the nitrofurazone and saline groups (25%). It can be concluded that dressing with a bittermelon extract is more efficient in the treatment of wounds than using nitrofurazone or saline, and that dressing with olive oil accelerateswound healing, although not as much as dressing with bitter melon extract.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | GÜRLEK KISACIK Ö, GÜNEŞ Ü, YAPRAKÇI M, ALTUNBAŞ K (2018). Effectiveness of bitter melon extract in the treatment of ischemic wounds in rats. , 506 - 516. 10.3906/biy-1804-36 |
| Chicago | GÜRLEK KISACIK Öznur,GÜNEŞ Ülkü,YAPRAKÇI Mustafa Volkan,ALTUNBAŞ Korhan Effectiveness of bitter melon extract in the treatment of ischemic wounds in rats. (2018): 506 - 516. 10.3906/biy-1804-36 |
| MLA | GÜRLEK KISACIK Öznur,GÜNEŞ Ülkü,YAPRAKÇI Mustafa Volkan,ALTUNBAŞ Korhan Effectiveness of bitter melon extract in the treatment of ischemic wounds in rats. , 2018, ss.506 - 516. 10.3906/biy-1804-36 |
| AMA | GÜRLEK KISACIK Ö,GÜNEŞ Ü,YAPRAKÇI M,ALTUNBAŞ K Effectiveness of bitter melon extract in the treatment of ischemic wounds in rats. . 2018; 506 - 516. 10.3906/biy-1804-36 |
| Vancouver | GÜRLEK KISACIK Ö,GÜNEŞ Ü,YAPRAKÇI M,ALTUNBAŞ K Effectiveness of bitter melon extract in the treatment of ischemic wounds in rats. . 2018; 506 - 516. 10.3906/biy-1804-36 |
| IEEE | GÜRLEK KISACIK Ö,GÜNEŞ Ü,YAPRAKÇI M,ALTUNBAŞ K "Effectiveness of bitter melon extract in the treatment of ischemic wounds in rats." , ss.506 - 516, 2018. 10.3906/biy-1804-36 |
| ISNAD | GÜRLEK KISACIK, Öznur vd. "Effectiveness of bitter melon extract in the treatment of ischemic wounds in rats". (2018), 506-516. https://doi.org/10.3906/biy-1804-36 |
| APA | GÜRLEK KISACIK Ö, GÜNEŞ Ü, YAPRAKÇI M, ALTUNBAŞ K (2018). Effectiveness of bitter melon extract in the treatment of ischemic wounds in rats. Turkish Journal of Biology, 42(6), 506 - 516. 10.3906/biy-1804-36 |
| Chicago | GÜRLEK KISACIK Öznur,GÜNEŞ Ülkü,YAPRAKÇI Mustafa Volkan,ALTUNBAŞ Korhan Effectiveness of bitter melon extract in the treatment of ischemic wounds in rats. Turkish Journal of Biology 42, no.6 (2018): 506 - 516. 10.3906/biy-1804-36 |
| MLA | GÜRLEK KISACIK Öznur,GÜNEŞ Ülkü,YAPRAKÇI Mustafa Volkan,ALTUNBAŞ Korhan Effectiveness of bitter melon extract in the treatment of ischemic wounds in rats. Turkish Journal of Biology, vol.42, no.6, 2018, ss.506 - 516. 10.3906/biy-1804-36 |
| AMA | GÜRLEK KISACIK Ö,GÜNEŞ Ü,YAPRAKÇI M,ALTUNBAŞ K Effectiveness of bitter melon extract in the treatment of ischemic wounds in rats. Turkish Journal of Biology. 2018; 42(6): 506 - 516. 10.3906/biy-1804-36 |
| Vancouver | GÜRLEK KISACIK Ö,GÜNEŞ Ü,YAPRAKÇI M,ALTUNBAŞ K Effectiveness of bitter melon extract in the treatment of ischemic wounds in rats. Turkish Journal of Biology. 2018; 42(6): 506 - 516. 10.3906/biy-1804-36 |
| IEEE | GÜRLEK KISACIK Ö,GÜNEŞ Ü,YAPRAKÇI M,ALTUNBAŞ K "Effectiveness of bitter melon extract in the treatment of ischemic wounds in rats." Turkish Journal of Biology, 42, ss.506 - 516, 2018. 10.3906/biy-1804-36 |
| ISNAD | GÜRLEK KISACIK, Öznur vd. "Effectiveness of bitter melon extract in the treatment of ischemic wounds in rats". Turkish Journal of Biology 42/6 (2018), 506-516. https://doi.org/10.3906/biy-1804-36 |
