TY  - JOUR
TI  - Effectiveness of bitter melon extract in the treatment of ischemic wounds in rats
AB  - There is no consensus on the properties of an ideal dressing for treating wounds. The aim of this study was to investigatethe efficacy of dressings using topically administered bitter melon extract with olive oil, pure olive oil, nitrofurazone, and saline in thehealing of ischemic wounds. A sample group of 48 rats was used in the trial. Their wounds were treated with bitter melon extract, pureolive oil, nitrofurazone, and saline. Data were collected between October 2014 and April 2015. The highest percentage (94.7%) of woundhealing was observed in the bitter melon extract group and the lowest percentage (86.3%) in the nitrofurazone group. At the end of the21st day, macroscopic reepithelialization was observed in 9 wounds in the bitter melon extract group (75%), in 6 wounds in the pureolive oil group (50%), and in only 3 wounds in the nitrofurazone and saline groups (25%). It can be concluded that dressing with a bittermelon extract is more efficient in the treatment of wounds than using nitrofurazone or saline, and that dressing with olive oil accelerateswound healing, although not as much as dressing with bitter melon extract.
AU  - YAPRAKÇI, Mustafa Volkan
AU  - ALTUNBAŞ, Korhan
AU  - GÜRLEK KISACIK, Öznur
AU  - GÜNEŞ, Ülkü
DO  - 10.3906/biy-1804-36
PY  - 2018
JO  - Turkish Journal of Biology
VL  - 42
IS  - 6
SN  - 1300-0152
SP  - 506
EP  - 516
DB  - TRDizin
UR  - http://search/yayin/detay/349228
ER  -