TY  - JOUR
TI  - Assessment of cardiac autonomic functions by heart rate variability in patients with restless leg syndrome
AB  - Objective: The aim of the present study was to investigatecardiac autonomic effects in restless leg syndrome (RLS) usingheart rate variability (HRV).Methods: A total of 35 patients with RLS and 35 healthy individualswere enrolled in the study. The severity of RLS symptomswas assessed using the International Restless LegsSyndrome Study Group rating scale (IRLS). The correlationbetween the severity of RLS symptoms and HRV parametersmeasured on an electrocardiogram was analyzed.Results: There were no statistically significant differences betweenthe 2 groups with respect to age, gender, or body massindex. The mean heart rate was 85±7.1 bpm in the RLS groupcompared with 79.6±5.5 bpm in the control group (p=0.001).The standard deviation (SD) of all normal to normal (NN) intervals(SDNN), the mean of the deviation of 5-minute NN intervalsover the entire recording (SDNN index), and the SD ofthe average NN intervals calculated over a 5-minute period ofthe entire recording (SDANN) were significantly lower in theRLS group compared with the control group (p<0.05 for all).There were no statistically significant differences between the2 groups in the square root of the mean squared differences ofsuccessive NN intervals (RMSSD) and the proportion of adjacentRR intervals differing by >50 milliseconds in the 24-hourrecording (pNN50) values (p=0.119 and p=0.07, respectively).In patients with RLS, the low frequency (LF) power and LF/high frequency (HF) ratio were significantly higher than those inthe control group (2248.6±245.6 vs 712.1±346.3, 10.7±3.7 vs2.9±1.8; p<0.0001 and p<0.0001, respectively). Compared withthe control group, the RLS group had lower values for HF power,but the difference was not statistically significant (p=0.07). Theseverity of RLS symptoms was negatively correlated with theSDNN, SDANN index, and pNN50 (r=-0.453 and p=0.009, r=-0.340 and p=0.046, r=-0.446 and p=0.007, respectively), andpositively correlated with LF power (r=0.681 and p<0.0001).Conclusion: The study data demonstrated that cardiac autonomicimpairment is associated with RLS.
AU  - yildiz, cennet
AU  - Karakurt, Ahmet
AU  - YILDIZ, Abdülmelik
DO  - 10.5543/tkda.2018.33896
PY  - 2018
JO  - Türk Kardiyoloji Derneği Arşivi
VL  - 46
IS  - 3
SN  - 1016-5169
SP  - 191
EP  - 196
DB  - TRDizin
UR  - http://search/yayin/detay/351568
ER  -