Body mass index is decreased in children and adolescents with postural tachycardia syndrome

JİAO, Fuyong; LİN, Jing; ZHAO, Huacai; MA, Lei

doi:10.24953/turkjped.2019.01.009

Body mass index is decreased in children and adolescents with postural tachycardia syndrome

Jing Lin, (Third Affiliated Hospital of Medical College, Xi’an Jiaotong University, Xi’an, China)

Huacai Zhao, (Third Affiliated Hospital of Medical College, Xi’an Jiaotong University, Xi’an, China)

Lei Ma, (Third Affiliated Hospital of Medical College, Xi’an Jiaotong University, Xi’an, China)

Fuyong Jiao (Third Affiliated Hospital of Medical College, Xi’an Jiaotong University, Xi’an, China)

Turkish Journal of Pediatrics

0 0

Yıl: 2019 Cilt: 61 Sayı: 1 Sayfa Aralığı: 52 - 58 Metin Dili: İngilizce DOI: 10.24953/turkjped.2019.01.009 İndeks Tarihi: 04-08-2020

Body mass index is decreased in children and adolescents with postural tachycardia syndrome

Öz:

Our intent was to explore the predictive value of body mass index (BMI)in differentiating between vasovagal syncope (VVS) and postural tachycardiasyndrome (POTS) in children and adolescents. A total of 111 children andadolescents with POTS and 154 children and adolescents with VVS wereincluded in our study. The control group included 82 healthy children andadolescents. Height and weight were measured in all participants. The headup tilt test was performed in participants in all groups (POTS, VVS, andcontrol). BMI was significantly lower in children and adolescents with POTS(18.3±3.4) than in children and adolescents with VVS (20.3±4.2) and thecontrol group (20.5±2.9). The receiver operating characteristic curve wasperformed to determine the predictive value of BMI differentiation betweenPOTS and VVS and showed that a BMI of 19.30 was the cutoff value forthe probability of distinction. However, the results (BMI of 19.30) producedunsatisfactory sensitivity (57.1%) and specificity (28.8%) rates of correctlydiscriminating between patients with POTS and patients with VVS. Childrenand adolescents with POTS have a lower BMI compared with healthy peersor children and adolescents with VVS.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

1. Low PA, Sandroni P, Joyner M, Shen WK. Postural tachycardia syndrome (POTS). J Cardiovasc Electrophysiol 2009; 20: 352-358.
2. Jarjour IT. Postural tachycardia syndrome in children and adolescents. Semin Pediatr Neurol 2013; 20: 18- 26.
3. Stewart JM. Common syndromes of orthostatic intolerance. Pediatrics 2013; 131: 968-980.
4. Folino AF, Russo G, Porta A, Buja G, Cerutti S, Iliceto S. Modulations of autonomic activity leading to tiltmediated syncope. Int J Cardiol 2007; 120: 102-107.
5. Christou GA, Kiortsis DN. The effects of body weight status on orthostatic intolerance and predisposition to noncardiac syncope. Obes Rev 2017; 18: 370-379.
6. Stewart JM, Taneja I, Medow MS. Reduced body mass index is associated with increased angiotensin II in young women with postural tachycardia syndrome. Clin Sci (Lond) 2007; 113: 449-457.
7. Zhang F, Li X, Stella C, et al. Plasma hydrogen sulfide in differential diagnosis between vasovagal syncope and postural orthostatic tachycardia syndrome in children. J Pediatr 2012; 160: 227-231.
8. Li H, Han Z, Chen S, et al. Total peripheral vascular resistance, cardiac output, and plasma C-type natriuretic Peptide level in children with postural tachycardia syndrome. J Pediatr 2015; 166: 1385-1389.e1-2.
9. Zhao J, Du S, Yang J, et al. Usefulness of plasma copeptin as a biomarker to predict the therapeutic effectiveness of metoprolol for postural tachycardia syndrome in children. Am J Cardiol 2014; 114: 601- 605.
10. Lin J, Wang Y, Ochs T, Tang C, Du J, Jin H. Tilt angles and positive response of head-up tilt test in children with orthostatic intolerance. Cardiol Young 2015; 25: 76-80.
11. Medow MS, Merchant S, Suggs M, Terilli C, O’DonnellSmith B, Stewart JM. Postural heart rate changes in young patients with vasovagal syncope. Pediatrics 2017; 139: pii: e20163189.
12. Stewart JM. Mechanisms of sympathetic regulation in orthostatic intolerance. J Appl Physiol (1985) 2012; 113: 1659-1668.
13. Furlan R, Jacob G, Snell M, et al. Chronic orthostatic intolerance: A disorder with discordant cardiac and vascular sympathetic control. Circulation 1998; 98: 2154-2159.
14. Claydon VE, Hainsworth R. Salt supplementation improves orthostatic cerebral and peripheral vascular control in patients with syncope. Hypertension 2004; 43: 809-813.
15. Li JW, Zhang QY, Gao J, Jin HF, Du JB. Significance of serum iron in the differential diagnosis between vasovagal syncope and postural orthostatic tachycardia syndrome in children. Beijing Da Xue Xue Bao Yi Xue Ban 2013; 45: 923-927.
16. Goossens GH, Blaak EE, Saris WH, van Baak MA. Angiotensin II-induced effects on adipose and skeletal muscle tissue blood flow and lipolysis innormal-weight and obese subjects. J Clin Endocrinol Metab 2004; 89: 2690-2696.
17. Porter JP, Potratz KR. Effect of intracerebroventricular angiotensin II on body weight and food intake in adult rats. Am J Physiol Regul Integr Comp Physiol 2004; 287: R422-R428.
18. North KE, Rose KM, Borecki IB, et al. Evidence for a gene on chromosome 13 influencing postural systolic blood pressure change and body mass index. Hypertension 2004 ;43: 780-784.
19. Geloneze B, Tambascia MA, Pareja JC, Repetto EM, Magna LA, Pereira SG. Serum leptin levels after bariatric surgery across a range of glucose tolerance from normal to diabetes. Obes Surg 2001; 11: 693-698.
20. Dunbar JC, Hu Y, Lu H. Intracerebroventricular leptin increases lumbar and renal sympathetic nerve activity and blood pressure in normal rats. Diabetes 1997; 46: 2040-2043.
21. Paolisso G, Manzella D, Montano N, Gambardella A, Varricchio M. Plasma leptin concentrations and cardiac autonomic nervous system in healthy subjects with different body weights. J Clin Endocrinol Metab 2000; 85: 1810-1814.
22. Frühbeck G. Pivotal role of nitric oxide in the control of blood pressure after leptin administration. Diabetes 1999; 48: 903-908.
23. Tschöp M, Weyer C, Tataranni PA, Devanarayan V, Ravussin E, Heiman ML. Circulating ghrelin levels are decreased in human obesity. Diabetes 2001; 50: 707-709.

APA	LİN J, ZHAO H, MA L, JİAO F (2019). Body mass index is decreased in children and adolescents with postural tachycardia syndrome. , 52 - 58. 10.24953/turkjped.2019.01.009
Chicago	LİN Jing,ZHAO Huacai,MA Lei,JİAO Fuyong Body mass index is decreased in children and adolescents with postural tachycardia syndrome. (2019): 52 - 58. 10.24953/turkjped.2019.01.009
MLA	LİN Jing,ZHAO Huacai,MA Lei,JİAO Fuyong Body mass index is decreased in children and adolescents with postural tachycardia syndrome. , 2019, ss.52 - 58. 10.24953/turkjped.2019.01.009
AMA	LİN J,ZHAO H,MA L,JİAO F Body mass index is decreased in children and adolescents with postural tachycardia syndrome. . 2019; 52 - 58. 10.24953/turkjped.2019.01.009
Vancouver	LİN J,ZHAO H,MA L,JİAO F Body mass index is decreased in children and adolescents with postural tachycardia syndrome. . 2019; 52 - 58. 10.24953/turkjped.2019.01.009
IEEE	LİN J,ZHAO H,MA L,JİAO F "Body mass index is decreased in children and adolescents with postural tachycardia syndrome." , ss.52 - 58, 2019. 10.24953/turkjped.2019.01.009
ISNAD	LİN, Jing vd. "Body mass index is decreased in children and adolescents with postural tachycardia syndrome". (2019), 52-58. https://doi.org/10.24953/turkjped.2019.01.009

APA	LİN J, ZHAO H, MA L, JİAO F (2019). Body mass index is decreased in children and adolescents with postural tachycardia syndrome. Turkish Journal of Pediatrics, 61(1), 52 - 58. 10.24953/turkjped.2019.01.009
Chicago	LİN Jing,ZHAO Huacai,MA Lei,JİAO Fuyong Body mass index is decreased in children and adolescents with postural tachycardia syndrome. Turkish Journal of Pediatrics 61, no.1 (2019): 52 - 58. 10.24953/turkjped.2019.01.009
MLA	LİN Jing,ZHAO Huacai,MA Lei,JİAO Fuyong Body mass index is decreased in children and adolescents with postural tachycardia syndrome. Turkish Journal of Pediatrics, vol.61, no.1, 2019, ss.52 - 58. 10.24953/turkjped.2019.01.009
AMA	LİN J,ZHAO H,MA L,JİAO F Body mass index is decreased in children and adolescents with postural tachycardia syndrome. Turkish Journal of Pediatrics. 2019; 61(1): 52 - 58. 10.24953/turkjped.2019.01.009
Vancouver	LİN J,ZHAO H,MA L,JİAO F Body mass index is decreased in children and adolescents with postural tachycardia syndrome. Turkish Journal of Pediatrics. 2019; 61(1): 52 - 58. 10.24953/turkjped.2019.01.009
IEEE	LİN J,ZHAO H,MA L,JİAO F "Body mass index is decreased in children and adolescents with postural tachycardia syndrome." Turkish Journal of Pediatrics, 61, ss.52 - 58, 2019. 10.24953/turkjped.2019.01.009
ISNAD	LİN, Jing vd. "Body mass index is decreased in children and adolescents with postural tachycardia syndrome". Turkish Journal of Pediatrics 61/1 (2019), 52-58. https://doi.org/10.24953/turkjped.2019.01.009