TY - JOUR TI - Comparison of the Essential Oils of Ferula orientalis L., Ferulago sandrasica Peşmen and Quézel, and Hippomarathrum microcarpum Petrov and Their Antimicrobial Activity AB - Objectives: To determine the chemical composition and antimicrobial activity of the essential oils of the aerial parts of Ferula orientalis L., roots ofFerulago sandrasica Peşmen and Quézel, and aerial parts of Hippomarathrum microcarpum Petrov.Materials and Methods: Essential oils were analyzed by gas chromatography and gas chromatography/mass spectrometry. The antimicrobialactivity of the essential oils was determined by bioautography assay.Results: α-Pinene (75.9%) and β-pinene (3.4%) were the major components of the aerial parts of F. orientalis; with limonene (28.9%), α-pinene(15.6%), and terpinolene (13.9%) for F. sandrasica; and β-caryophyllene (31.4%) and caryophyllene oxide (23.1%) for the aerial parts of H. microcarpum.Essential oils from the aerial parts of F. orientalis, the roots of F. sandrasica, and the aerial parts of H. microcarpum were active against Staphylococcusaureus and Candida albicans strains. However, essential oils were not active against Pseudomonas aeruginosa or Escherichia coli.Conclusion: The antimicrobial activities against S. aureus and C. albicans of these species may be attributed to the presence of the main componentsin the essential oils. AU - Demirci, Betül AU - KARAKAYA, Songül AU - BOSTANLIK, Fatmagül D. AU - DUMAN, HAYRI AU - GÖGER, Gamze AU - KILIÇ, Ceyda Sibel DO - 10.4274/tjps.77200 PY - 2019 JO - Turkish Journal of Pharmaceutical Sciences VL - 16 IS - 1 SN - 1304-530X SP - 69 EP - 75 DB - TRDizin UR - http://search/yayin/detay/354156 ER -