The Geometry of the Circle of Willis Anatomical Variants as a Potential Cerebrovascular Risk Factor

BARTOS, Adrian; PASCALAU, Raluca; SZABO, Bianca Aurora; BARTOS, Dana; PADUREAN, Vlad Adrian

doi:10.5137/1019-5149.JTN.21835-17.3

The Geometry of the Circle of Willis Anatomical Variants as a Potential Cerebrovascular Risk Factor

Raluca PASCALAU, (Iuliu Hatieganu” University of Medicine and Pharmacy, Faculty of Medicine, Cluj-Napoca, Romania)

Vlad Adrian PADUREAN, (Iuliu Hatieganu” University of Medicine and Pharmacy, Faculty of Medicine, Cluj-Napoca, Romania)

Dana BARTOS, (Iuliu Hatieganu” University of Medicine and Pharmacy, Department of Anatomy and Embryology, Cluj-Napoca, Romania)

Adrian BARTOS, (Regional Institute of Gastroenterology and Hepatology, Department of Surgery, Cluj-Napoca, Romania)

Bianca Aurora SZABO (Emergency County Hospital Cluj, Department of Ophthalmology, Cluj-Napoca, Romania)

Turkish Neurosurgery

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Yıl: 2019 Cilt: 29 Sayı: 2 Sayfa Aralığı: 151 - 158 Metin Dili: İngilizce DOI: 10.5137/1019-5149.JTN.21835-17.3 İndeks Tarihi: 06-09-2020

The Geometry of the Circle of Willis Anatomical Variants as a Potential Cerebrovascular Risk Factor

Öz:

AIM: To correlate the anatomical variants of the circle of Willis with their effects on the hemodynamic and geometrical parametersresponsible for the pathogenesis of neurological diseases.MATERIAL and METHODS: The circle of Willis and the proximal segments of the main arteries were dissected and measured onten formalin-fixed human brains. The anatomical variants were systematized using descriptive statistics. The mathematical modelsfor brain perfusion and wall shear stress were developed by optimally approximating resistance to flow, vascular conductance, andbranching.RESULTS: Eighty percent of the brains presented asymmetries, especially in the posterior communicating (70%) and anteriorcerebral (40%) arteries. The posterior circulation had more variations (65.21%). Nine hypoplastic vessels were found in 7 brains.Atypical origins were observed in eight specimens. According to the mathematical models, which integrated each anatomicalchange in the global circle of Willis anatomy, the circle of Willis’ geometry could represent a risk factor for intracranial aneurysms andatherosclerosis, mostly when hypoplastic arteries are present, due to high resistance to flow and imbalanced bifurcation geometry.Accessory vessels are less associated with cerebrovascular risk.CONCLUSION: We described anatomical variants of both the anterior and posterior circulations and their specific effects on thehemodynamic balance of cerebral blood flow.

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Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	PASCALAU R, PADUREAN V, BARTOS D, BARTOS A, SZABO B (2019). The Geometry of the Circle of Willis Anatomical Variants as a Potential Cerebrovascular Risk Factor. , 151 - 158. 10.5137/1019-5149.JTN.21835-17.3
Chicago	PASCALAU Raluca,PADUREAN Vlad Adrian,BARTOS Dana,BARTOS Adrian,SZABO Bianca Aurora The Geometry of the Circle of Willis Anatomical Variants as a Potential Cerebrovascular Risk Factor. (2019): 151 - 158. 10.5137/1019-5149.JTN.21835-17.3
MLA	PASCALAU Raluca,PADUREAN Vlad Adrian,BARTOS Dana,BARTOS Adrian,SZABO Bianca Aurora The Geometry of the Circle of Willis Anatomical Variants as a Potential Cerebrovascular Risk Factor. , 2019, ss.151 - 158. 10.5137/1019-5149.JTN.21835-17.3
AMA	PASCALAU R,PADUREAN V,BARTOS D,BARTOS A,SZABO B The Geometry of the Circle of Willis Anatomical Variants as a Potential Cerebrovascular Risk Factor. . 2019; 151 - 158. 10.5137/1019-5149.JTN.21835-17.3
Vancouver	PASCALAU R,PADUREAN V,BARTOS D,BARTOS A,SZABO B The Geometry of the Circle of Willis Anatomical Variants as a Potential Cerebrovascular Risk Factor. . 2019; 151 - 158. 10.5137/1019-5149.JTN.21835-17.3
IEEE	PASCALAU R,PADUREAN V,BARTOS D,BARTOS A,SZABO B "The Geometry of the Circle of Willis Anatomical Variants as a Potential Cerebrovascular Risk Factor." , ss.151 - 158, 2019. 10.5137/1019-5149.JTN.21835-17.3
ISNAD	PASCALAU, Raluca vd. "The Geometry of the Circle of Willis Anatomical Variants as a Potential Cerebrovascular Risk Factor". (2019), 151-158. https://doi.org/10.5137/1019-5149.JTN.21835-17.3

APA	PASCALAU R, PADUREAN V, BARTOS D, BARTOS A, SZABO B (2019). The Geometry of the Circle of Willis Anatomical Variants as a Potential Cerebrovascular Risk Factor. Turkish Neurosurgery, 29(2), 151 - 158. 10.5137/1019-5149.JTN.21835-17.3
Chicago	PASCALAU Raluca,PADUREAN Vlad Adrian,BARTOS Dana,BARTOS Adrian,SZABO Bianca Aurora The Geometry of the Circle of Willis Anatomical Variants as a Potential Cerebrovascular Risk Factor. Turkish Neurosurgery 29, no.2 (2019): 151 - 158. 10.5137/1019-5149.JTN.21835-17.3
MLA	PASCALAU Raluca,PADUREAN Vlad Adrian,BARTOS Dana,BARTOS Adrian,SZABO Bianca Aurora The Geometry of the Circle of Willis Anatomical Variants as a Potential Cerebrovascular Risk Factor. Turkish Neurosurgery, vol.29, no.2, 2019, ss.151 - 158. 10.5137/1019-5149.JTN.21835-17.3
AMA	PASCALAU R,PADUREAN V,BARTOS D,BARTOS A,SZABO B The Geometry of the Circle of Willis Anatomical Variants as a Potential Cerebrovascular Risk Factor. Turkish Neurosurgery. 2019; 29(2): 151 - 158. 10.5137/1019-5149.JTN.21835-17.3
Vancouver	PASCALAU R,PADUREAN V,BARTOS D,BARTOS A,SZABO B The Geometry of the Circle of Willis Anatomical Variants as a Potential Cerebrovascular Risk Factor. Turkish Neurosurgery. 2019; 29(2): 151 - 158. 10.5137/1019-5149.JTN.21835-17.3
IEEE	PASCALAU R,PADUREAN V,BARTOS D,BARTOS A,SZABO B "The Geometry of the Circle of Willis Anatomical Variants as a Potential Cerebrovascular Risk Factor." Turkish Neurosurgery, 29, ss.151 - 158, 2019. 10.5137/1019-5149.JTN.21835-17.3
ISNAD	PASCALAU, Raluca vd. "The Geometry of the Circle of Willis Anatomical Variants as a Potential Cerebrovascular Risk Factor". Turkish Neurosurgery 29/2 (2019), 151-158. https://doi.org/10.5137/1019-5149.JTN.21835-17.3