Synthesis, characterization and theoretical studies of novelsulfonamide-aldehydes derivatives having tautomeric forms

SERT, YUSUF; Gümüş, Mehmet; KOCA, IRFAN

doi:10.25135/acg.oc.67.19.09.1407

Synthesis, characterization and theoretical studies of novelsulfonamide-aldehydes derivatives having tautomeric forms

Mehmet Gümüş, (Akdagmadeni Health College, Yozgat Bozok University, Yozgat, Türkiye)

Yusuf Sert, (Sorgun Vocational School, Yozgat Bozok University, Yozgat, Türkiye)

İrfan Koca (Department of Chemistry, Faculty of Art & Sciences, Yozgat Bozok University, Yozgat, Türkiye)

Organic Communications

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Yıl: 2019 Cilt: 12 Sayı: 4 Sayfa Aralığı: 167 - 187 Metin Dili: İngilizce DOI: 10.25135/acg.oc.67.19.09.1407 İndeks Tarihi: 08-09-2020

Synthesis, characterization and theoretical studies of novelsulfonamide-aldehydes derivatives having tautomeric forms

Öz:

The newly synthesized six tautomeric aldehydeswere characterized by1H NMR and13C NMRspectra.As a result of experimental characterization studies of target products, two tautomer structures named enol-azo and keto-hydrazo were observed.To support other experimental quantum chemical computations were utilized by Density Functional Theory using B3LYP functional and 6-311++G (d,p) basis set. All theoretical calculations were performed only for molecules M1and M4after each tautomerwas optimized. The form IIItautomerswith lower energy of compounds M1and M4were determined as preferential structuresin the ground state. From the MEP analysis, it is evident that the negative charge covers the C=O group and positive region is over the hydrogen groups. Finally, molecular docking calculations between 4F5S receptor and six ligand interactions were carried out by using AutoDockVina program, and results were evaluated in detail

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Gümüş M, SERT Y, KOCA I (2019). Synthesis, characterization and theoretical studies of novelsulfonamide-aldehydes derivatives having tautomeric forms. , 167 - 187. 10.25135/acg.oc.67.19.09.1407
Chicago	Gümüş Mehmet,SERT YUSUF,KOCA IRFAN Synthesis, characterization and theoretical studies of novelsulfonamide-aldehydes derivatives having tautomeric forms. (2019): 167 - 187. 10.25135/acg.oc.67.19.09.1407
MLA	Gümüş Mehmet,SERT YUSUF,KOCA IRFAN Synthesis, characterization and theoretical studies of novelsulfonamide-aldehydes derivatives having tautomeric forms. , 2019, ss.167 - 187. 10.25135/acg.oc.67.19.09.1407
AMA	Gümüş M,SERT Y,KOCA I Synthesis, characterization and theoretical studies of novelsulfonamide-aldehydes derivatives having tautomeric forms. . 2019; 167 - 187. 10.25135/acg.oc.67.19.09.1407
Vancouver	Gümüş M,SERT Y,KOCA I Synthesis, characterization and theoretical studies of novelsulfonamide-aldehydes derivatives having tautomeric forms. . 2019; 167 - 187. 10.25135/acg.oc.67.19.09.1407
IEEE	Gümüş M,SERT Y,KOCA I "Synthesis, characterization and theoretical studies of novelsulfonamide-aldehydes derivatives having tautomeric forms." , ss.167 - 187, 2019. 10.25135/acg.oc.67.19.09.1407
ISNAD	Gümüş, Mehmet vd. "Synthesis, characterization and theoretical studies of novelsulfonamide-aldehydes derivatives having tautomeric forms". (2019), 167-187. https://doi.org/10.25135/acg.oc.67.19.09.1407

APA	Gümüş M, SERT Y, KOCA I (2019). Synthesis, characterization and theoretical studies of novelsulfonamide-aldehydes derivatives having tautomeric forms. Organic Communications, 12(4), 167 - 187. 10.25135/acg.oc.67.19.09.1407
Chicago	Gümüş Mehmet,SERT YUSUF,KOCA IRFAN Synthesis, characterization and theoretical studies of novelsulfonamide-aldehydes derivatives having tautomeric forms. Organic Communications 12, no.4 (2019): 167 - 187. 10.25135/acg.oc.67.19.09.1407
MLA	Gümüş Mehmet,SERT YUSUF,KOCA IRFAN Synthesis, characterization and theoretical studies of novelsulfonamide-aldehydes derivatives having tautomeric forms. Organic Communications, vol.12, no.4, 2019, ss.167 - 187. 10.25135/acg.oc.67.19.09.1407
AMA	Gümüş M,SERT Y,KOCA I Synthesis, characterization and theoretical studies of novelsulfonamide-aldehydes derivatives having tautomeric forms. Organic Communications. 2019; 12(4): 167 - 187. 10.25135/acg.oc.67.19.09.1407
Vancouver	Gümüş M,SERT Y,KOCA I Synthesis, characterization and theoretical studies of novelsulfonamide-aldehydes derivatives having tautomeric forms. Organic Communications. 2019; 12(4): 167 - 187. 10.25135/acg.oc.67.19.09.1407
IEEE	Gümüş M,SERT Y,KOCA I "Synthesis, characterization and theoretical studies of novelsulfonamide-aldehydes derivatives having tautomeric forms." Organic Communications, 12, ss.167 - 187, 2019. 10.25135/acg.oc.67.19.09.1407
ISNAD	Gümüş, Mehmet vd. "Synthesis, characterization and theoretical studies of novelsulfonamide-aldehydes derivatives having tautomeric forms". Organic Communications 12/4 (2019), 167-187. https://doi.org/10.25135/acg.oc.67.19.09.1407