TY  - JOUR
TI  - Artificial Total Disc Replacement Versus Fusion for Lumbar Degenerative Disc Disease: An Update Systematic Review and Meta-Analysis
AB  - AIM: To conduct an updated systematic review and meta-analysis to compare the efficacy and safety between total disc replacement(TDR) and fusion surgery for lumbar degenerative disc disease (LDDD).MATERIAL and METHODS: We comprehensively searched meta-analyses comparing TDR with fusion through the PubMed,Embase, and Cochrane Library databases. Only randomized controlled trials (RCTs) were selected and collected. The end of theretrieval time was June 2017. Two authors independently extracted the data from the studies after assessing their quality. Thestatistical software STATA version 12.0 was used to analyze the data.RESULTS: A total of seven RCTs (1706 patients) were included in our analysis. The patients in the TDR group had significantlyimproved. A greater percentage of these patients were satisfied with the surgery concerning Oswestry disability index, visual analogscale score, and complication rate. In addition, the clinical success in the TDR group was greater than that in the fusion group.Meanwhile, the TDR group had shorter operative time and hospital stay. However, there was no clinical significance regarding bloodloss, work status, and reoperation rate between the two groups.CONCLUSION: Our current updated meta-analysis suggests that TDR could be an alternative treatment for LDDD, since it yieldedbetter clinical success and patient satisfaction, shorter hospital stay and operative time, less pain, and lower complication ratesthan lumbar fusion.
AU  - TANG, Li
AU  - LI, Yu Zhe
AU  - CHEN, Chun Hui
AU  - CHEN, Dong
AU  - SUN, Piao
AU  - WU, Ai-Min
DO  - 10.5137/1019-5149.JTN.24799-18.2
PY  - 2020
JO  - Turkish Neurosurgery
VL  - 30
IS  - 1
SN  - 1019-5149
SP  - 1
EP  - 10
DB  - TRDizin
UR  - http://search/yayin/detay/356644
ER  -