Significance of hemogram on diagnosis of acute appendicitis during pregnancy
Yıl: 2018 Cilt: 24 Sayı: 5 Sayfa Aralığı: 423 - 428 Metin Dili: İngilizce DOI: 10.5505/tjtes.2018.62753 İndeks Tarihi: 17-09-2020
Significance of hemogram on diagnosis of acute appendicitis during pregnancy
Öz: BACKGROUND: Acute appendicitis (AA) is the most common emergency surgical condition during pregnancy after obstetric andgynecological pathologies. Urgent and accurate diagnosis of AA in pregnant patients reduces maternal and fetal morbidity/mortalityrates. This study evaluated the significance of hemogram to diagnose AA during pregnancy.METHODS: Forty-seven pregnant patients operated for AA in the Ordu or Ondokuz Mayis University Medical School Hospitalsbetween January 2007 and December 2017 were compared with 47 healthy pregnant women in terms of hemogram parameters, including the white blood cell (WBC) count, neutrophil count, lymphocyte count, platelet count, neutrophil-to-lymphocyte ratio (NLR),platelet-to-lymphocyte ratio (PLR), mean platelet volume (MPV), and red cell distribution width (RDW) values. The operated groupwas evaluated based on post-operative pathologic results and subclassified into appendicitis positive (Group A) and appendicitis negative (Group B) groups. The subgroups were compared to the control group.RESULTS: The WBC and neutrophil count and mean NLR and PLR values were significantly higher in Group A compared to Group Band the control group (p<0.001). The mean lymphocyte count was significantly lower in Group A compared to other groups (p<0.001).The MPV and RDW values and mean platelet count showed no significant difference between groups (p>0.05). When cutoff valuesfor WBC, neutrophil count, NLR, PLR, and lymphocyte counts were set to >10300, >7950, >5.50, >155.2, and ≤1330, respectively,the sensitivity rates were 72.5%, 80%, 90%, 77.5% and 85%, whereas specificity rates were 72.3%, 79.7%, 89.4%, 74.5%, and 82.5%,respectively.CONCLUSION: When comparing pregnant women diagnosed with AA to patients operated for suspected AA and healthy pregnantwomen, the WBC and neutrophil count and NLR and PLR values were found to be significantly higher, whereas lymphocyte countswere lower. In addition to medical history, physical examination and imaging techniques, hemogram parameters should be consideredto diagnose AA in pregnant women.
Anahtar Kelime: Gebelikte hemogramın akut apandisit tanısındaki önemi
Öz: AMAÇ: Akut apandisit (AA) gebelik döneminde obstetrik ve jinekolojik patolojilerden sonra en sık acil cerrahi gerektiren durumdur. Gebe hastalarda AA tanısının hızlı ve doğru konulması maternal ve fetal morbite/mortalite oranlarını azaltır. Bu çalışma, hemogramın gebelik döneminde AA tanısı koymadaki önemini irdelemektedir. GEREÇ VE YÖNTEM: Ordu veya Ondokuz Mayıs Üniversitesi Tıp Fakültesi Hastanesi’nde Ocak 2007–Aralık 2017 yılları arasında AA nedeniyle ameliyat edilen 47 gebe hasta ile 47 sağlıklı gebe hastanın hemogram parametrelerinden beyaz kan hücresi (WBC) sayısı, nötrofil sayısı, lenfosit sayısı, platelet sayısı, nötrofil/lenfosit oranı (NLO), platelet/lenfosit oranı (PLO), mean platelet volüm (MPV) ve kırmızı hücre dağıtım genişliği (RDW) değerleri kıyaslandı. Ameliyat edilen hastalar, patoloji sonucu apandisit olanlar Grup A normal olanlar ise Grup B olarak ikiye ayrıldı ve kontrol grubu ile kıyaslandı. BULGULAR: Grup A hastalarının WBC sayısı, nötrofil sayısı, ortalama NLO ve PLO değerleri Grup B ve kontrol hastalarından anlamlı olarak yüksek tespit edildi (p<0.001). Lenfosit sayısı ortalamasının Grup A hastalarında diğer gruplardan anlamlı olarak düşük olduğu görüldü (p<0.001). MPV, RDW ve ortalama platelet sayısı açısından gruplar arasında anlamlı bir farklılık yoktu (p>0.05). WBC sayısı, nötrofil sayısı, NLO, PLO ve lenfosit sayısı için kestirim değerleri sırasıyla >10300, >7950, >5.50, >155.2 ve ≤1330 olarak alındığında sensivite oranları sırasıyla %72.5, %80, %90, %77.5 ve %85 olarak gözlenirken spesifite oranları ise sırasıyla %72.3, %79.7, %89.4, %74.5 ve %82.5 olarak tespit edildi. TARTIŞMA: Akut apandisit tanısı olan gebe kadınlarda WBC sayısı, nötrofil sayısı, NLO ve PLO değerleri kontrol grubu ve apandisit şüphesi nedeniyle ameliyat edilen hastalardan istatistiksel olarak anlamlı olacak şekilde yüksek bulunurken lenfosit sayısı ise düşük bulunmuştur. Gebe kadınlarda AA tanısı koymak için anamnez, fizik muayene ve görüntüleme yöntemleri ile birlikte hemogram parametreleride göz önünde bulundurulmalıdır
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Cinar H, Aygun A, derebey m, tarım i, Akalin C, Büyükakıncak S, ERZURUMLU K (2018). Significance of hemogram on diagnosis of acute appendicitis during pregnancy. , 423 - 428. 10.5505/tjtes.2018.62753 |
| Chicago | Cinar Hamza,Aygun Ali,derebey murat,tarım ismail alper,Akalin Cagri,Büyükakıncak Sercan,ERZURUMLU KENAN Significance of hemogram on diagnosis of acute appendicitis during pregnancy. (2018): 423 - 428. 10.5505/tjtes.2018.62753 |
| MLA | Cinar Hamza,Aygun Ali,derebey murat,tarım ismail alper,Akalin Cagri,Büyükakıncak Sercan,ERZURUMLU KENAN Significance of hemogram on diagnosis of acute appendicitis during pregnancy. , 2018, ss.423 - 428. 10.5505/tjtes.2018.62753 |
| AMA | Cinar H,Aygun A,derebey m,tarım i,Akalin C,Büyükakıncak S,ERZURUMLU K Significance of hemogram on diagnosis of acute appendicitis during pregnancy. . 2018; 423 - 428. 10.5505/tjtes.2018.62753 |
| Vancouver | Cinar H,Aygun A,derebey m,tarım i,Akalin C,Büyükakıncak S,ERZURUMLU K Significance of hemogram on diagnosis of acute appendicitis during pregnancy. . 2018; 423 - 428. 10.5505/tjtes.2018.62753 |
| IEEE | Cinar H,Aygun A,derebey m,tarım i,Akalin C,Büyükakıncak S,ERZURUMLU K "Significance of hemogram on diagnosis of acute appendicitis during pregnancy." , ss.423 - 428, 2018. 10.5505/tjtes.2018.62753 |
| ISNAD | Cinar, Hamza vd. "Significance of hemogram on diagnosis of acute appendicitis during pregnancy". (2018), 423-428. https://doi.org/10.5505/tjtes.2018.62753 |
| APA | Cinar H, Aygun A, derebey m, tarım i, Akalin C, Büyükakıncak S, ERZURUMLU K (2018). Significance of hemogram on diagnosis of acute appendicitis during pregnancy. Ulusal Travma ve Acil Cerrahi Dergisi, 24(5), 423 - 428. 10.5505/tjtes.2018.62753 |
| Chicago | Cinar Hamza,Aygun Ali,derebey murat,tarım ismail alper,Akalin Cagri,Büyükakıncak Sercan,ERZURUMLU KENAN Significance of hemogram on diagnosis of acute appendicitis during pregnancy. Ulusal Travma ve Acil Cerrahi Dergisi 24, no.5 (2018): 423 - 428. 10.5505/tjtes.2018.62753 |
| MLA | Cinar Hamza,Aygun Ali,derebey murat,tarım ismail alper,Akalin Cagri,Büyükakıncak Sercan,ERZURUMLU KENAN Significance of hemogram on diagnosis of acute appendicitis during pregnancy. Ulusal Travma ve Acil Cerrahi Dergisi, vol.24, no.5, 2018, ss.423 - 428. 10.5505/tjtes.2018.62753 |
| AMA | Cinar H,Aygun A,derebey m,tarım i,Akalin C,Büyükakıncak S,ERZURUMLU K Significance of hemogram on diagnosis of acute appendicitis during pregnancy. Ulusal Travma ve Acil Cerrahi Dergisi. 2018; 24(5): 423 - 428. 10.5505/tjtes.2018.62753 |
| Vancouver | Cinar H,Aygun A,derebey m,tarım i,Akalin C,Büyükakıncak S,ERZURUMLU K Significance of hemogram on diagnosis of acute appendicitis during pregnancy. Ulusal Travma ve Acil Cerrahi Dergisi. 2018; 24(5): 423 - 428. 10.5505/tjtes.2018.62753 |
| IEEE | Cinar H,Aygun A,derebey m,tarım i,Akalin C,Büyükakıncak S,ERZURUMLU K "Significance of hemogram on diagnosis of acute appendicitis during pregnancy." Ulusal Travma ve Acil Cerrahi Dergisi, 24, ss.423 - 428, 2018. 10.5505/tjtes.2018.62753 |
| ISNAD | Cinar, Hamza vd. "Significance of hemogram on diagnosis of acute appendicitis during pregnancy". Ulusal Travma ve Acil Cerrahi Dergisi 24/5 (2018), 423-428. https://doi.org/10.5505/tjtes.2018.62753 |
