Antimicrobial activity of three Scutellaria L. species from Turkey

Zekiye ARITULUK, (Hacettepe Üniversitesi, Eczacılık Fakültesi, Farmasötik Botanik Anabilim Dalı, Ankara, Türkiye)
Ceren KOÇAK, (Hacettepe Üniversitesi, Eczacılık Fakültesi, Farmasötik Mikrobiyoloji Anabilim Dalı, Ankara, Türkiye)
Gülin RENDA, (Karadeniz Teknik Üniversitesi, Eczacılık Fakültesi, Farmakognozi Anabilim Dalı, Trabzon, Türkiye)
Melike EKİZOĞLU, (Hacettepe Üniversitesi, Eczacılık Fakültesi, Farmasötik Mikrobiyoloji Anabilim Dalı, Ankara, Türkiye)
Nurten EZER (Hacettepe Üniversitesi, Eczacılık Fakültesi, Farmasötik Botanik Anabilim Dalı, Ankara, Türkiye)
Journal of research in pharmacy (online)
6 0
Yıl: 2019 Cilt: 23 Sayı: 3 Sayfa Aralığı: 552 - 558 Metin Dili: İngilizce DOI: 10.12991/jrp.2019.162 İndeks Tarihi: 17-09-2020

Antimicrobial activity of three Scutellaria L. species from Turkey

Öz:
Plant-sourced antimicrobials are known for their therapeutic potency against multi-drug-resistantpathogens. The members of Scutellaria L. have been used to cure several diseases in East Asia, Europe, and NorthAmerica. The genus Scutellaria belonging to Lamiaceae family is composed of around 360 species worldwide and 18species in Turkey. In this study, 36 extracts prepared with different solvents from aerial parts and roots of S. salviifoliaBenth., S. diffusa Benth. and S. pontica C. Koch were investigated for their antimicrobial activity against four bacteria(Escherichia coli ATCC 25922, Enterococcus faecalis ATCC 29212, Pseudomonas aeruginosa ATCC 27853, Staphylococcusaureus ATCC 29213) and three yeasts (Candida albicans ATCC 90028, C. krusei ATCC 6258, C. parapsilosis ATCC 90018)by using the broth microdilution method. Gentamicin, vancomycin and fluconazole were used as positive control.According to our results, all of the tested extracts showed stronger antimicrobial activity against yeasts than bacteria.The chloroform extract of S. salviifolia root showed the highest antifungal effect against C. krusei with 32 μg/ml MICvalue compared with all the tested extracts and the positive control fluconazole (64 μg/ml MIC value).
Anahtar Kelime:

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  • [1] Subramani R, Narayanasamy M, Feussner K-D. Plant-derived antimicrobials to fight against multi-drug-resistant human pathogens. 3 Biotech. 2017; 7(3): 172. [CrossRef]
  • [2] Rios J, Recio M. Medicinal plants and antimicrobial activity. J Ethnopharmacol. 2005; 100(1-2): 80-84. [CrossRef]
  • [3] Paton A. A global taxonomic investigation of Scutellaria (Labiatae). Kew Bull. 1990; 45(3): 399-450. [CrossRef]
  • [4] Shang X, He X, He X, Li M, Zhang R, Fan P, Zhang Q, Jia Z. The genus Scutellaria an ethnopharmacological and phytochemical review. J Ethnopharmacol. 2010; 128(2): 279-313. [CrossRef]
  • [5] Joshee N, Patrick TS, Mentreddy RS, Yadav AK. Skullcap: Potential medicinal crop. In: Janick J, Whipkey A (Eds). Trends in New Crops and New Uses. ASHS Press, Alexandria, VA, 2002, pp.580-586.
  • [6] Çiçek M, Yaprak AE. Scutellaria yildirimlii (Lamiaceae), a new species from Turkey. Phytotaxa. 2013; 132(1): 53-58. [CrossRef]
  • [7] Güner A, Aslan S, Ekim T, Vural M, Babaç M, Türkiye Bitkileri Listesi (Damarlı Bitkiler), Flora Dizisi 1., ANG Vakfi, Nezahat Gökyiğit Botanik Bahçesi Yayınları, İstanbul, 2012.
  • [8] Tuzlacı E, Türkiye Bitkileri Geleneksel İlaç Rehberi, İstanbul Tıp Kitabevi, İstanbul, 2016.
  • [9] Altundag E, Ozturk M. Ethnomedicinal studies on the plant resources of east Anatolia, Turkey. Procedia Soc Behav Sci. 2011; 19: 756-777. [CrossRef]
  • [10] Cakilcioglu U, Turkoglu I. An ethnobotanical survey of medicinal plants in Sivrice (Elazığ-Turkey). J Ethnopharmacol. 2010; 132(1): 165-175. [CrossRef]
  • [11] Mükemre M, Behçet L, Çakılcıoğlu U. Ethnobotanical study on medicinal plants in villages of Çatak (Van-Turkey). J Ethnopharmacol. 2015; 166: 361-374. [CrossRef]
  • [12] Edmondson JR. Scutellaria L. In: Davis PH. (Eds). Flora of Turkey and the East Aegean Islands, Vol. 7, Edinburgh University Press, Edinburgh, 1982, pp. 78.
  • [13] Ersöz T, Harput ÜŞ, Saracoğlu İ, Çalış İ, Ogihara Y. Phenolic compounds from Scutellaria pontica. Turk J Chem. 2002; 26(4): 581-588.
  • [14] Rodríguez B, de la Torre MC, Jimeno M-L, Bruno M, Vassallo N, Bondì M, Piozzi F, Servettaz O. Neoclerodane diterpenoids from Scutellaria pontica. J Nat Prod. 1997; 60(4): 348-355.
  • [15] Cicek M, Demirci B, Yilmaz G, Baser KHC. Essential oil composition of three species of Scutellaria from Turkey. Nat Prod Res. 2011; 25(18): 1720-1726. [CrossRef]
  • [16] Saracoglu I, Inoue M, Calıs I, Ogihara Y. Studies on constituents with cytotoxic and cytostatic activity of two Turkish medicinal plants Phlomis armeniaca and Scutellaria salviifolia. Biol Pharm Bull. 1995; 18(10): 1396-1400. [CrossRef]
  • [17] Şenol FS, Orhan I, Yilmaz G, Cicek M, Şener B. Acetylcholinesterase, butyrylcholinesterase, and tyrosinase inhibition studies and antioxidant activities of 33 Scutellaria L. taxa from Turkey. Food Chem Toxicol. 2010; 48(3): 781-788. [CrossRef]
  • [18] Yavuz C, Dereli Kılıç DD, Ayar A, Yıldırım T. Antibacterial effects of methanol extracts of some plant species belonging to Lamiaceae family. Int J Sec Metabolite. 2017; 4(3): 429-433. [CrossRef]
  • [19] Clinical and Laboratory Standards Institute, Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically, Approved Standard 8th ed., M 07-A8, Clinical and Laboratory Standards Institute, Wayne, PA, 2008.
  • [20] Clinical and Laboratory Standards Institute, Reference method for broth dilution antifungal susceptibility testing of yeasts: approved Standard 3rd ed., M 27-A3, Clinical and Laboratory Standards Institute, Wayne, PA, 2008.
  • [21] Yang Z-C, Wang B-C, Yang X-S, Wang Q, Ran L. The synergistic activity of antibiotics combined with eight traditional Chinese medicines against two different strains of Staphylococcus aureus. Colloids Surf B Biointerfaces. 2005; 41(2-3): 79-81. [CrossRef]
  • [22] Trinh H, Yoo Y, Won K-H, Ngo HT, Yang J-E, Cho J-G, Lee S-W, Kim K-Y, Yi T-H. Evaluation of in-vitro antimicrobial activity of Artemisia apiacea H. and Scutellaria baicalensis G. extracts. J Med Microbiol. 2018; 67(4): 489-495. [CrossRef]
  • [23] Shan B, Cai Y-Z, Brooks JD, Corke H. The in vitro antibacterial activity of dietary spice and medicinal herb extracts. Int J Food Microbiol. 2007; 117(1): 112-119. [CrossRef]
  • [24] Lu Y, Joerger R, Wu C. Study of the chemical composition and antimicrobial activities of ethanolic extracts from roots of Scutellaria baicalensis Georgi. J Agric Food Chem. 2011; 59(20): 10934-10942. [CrossRef]
APA Arıtuluk Aydın Z, Ozkul Kocak C, Renda G, EKİZOĞLU M, EZER N (2019). Antimicrobial activity of three Scutellaria L. species from Turkey. , 552 - 558. 10.12991/jrp.2019.162
Chicago Arıtuluk Aydın Zekiye Ceren,Ozkul Kocak Ceren,Renda Gülin,EKİZOĞLU Melike,EZER Nurten Antimicrobial activity of three Scutellaria L. species from Turkey. (2019): 552 - 558. 10.12991/jrp.2019.162
MLA Arıtuluk Aydın Zekiye Ceren,Ozkul Kocak Ceren,Renda Gülin,EKİZOĞLU Melike,EZER Nurten Antimicrobial activity of three Scutellaria L. species from Turkey. , 2019, ss.552 - 558. 10.12991/jrp.2019.162
AMA Arıtuluk Aydın Z,Ozkul Kocak C,Renda G,EKİZOĞLU M,EZER N Antimicrobial activity of three Scutellaria L. species from Turkey. . 2019; 552 - 558. 10.12991/jrp.2019.162
Vancouver Arıtuluk Aydın Z,Ozkul Kocak C,Renda G,EKİZOĞLU M,EZER N Antimicrobial activity of three Scutellaria L. species from Turkey. . 2019; 552 - 558. 10.12991/jrp.2019.162
IEEE Arıtuluk Aydın Z,Ozkul Kocak C,Renda G,EKİZOĞLU M,EZER N "Antimicrobial activity of three Scutellaria L. species from Turkey." , ss.552 - 558, 2019. 10.12991/jrp.2019.162
ISNAD Arıtuluk Aydın, Zekiye Ceren vd. "Antimicrobial activity of three Scutellaria L. species from Turkey". (2019), 552-558. https://doi.org/10.12991/jrp.2019.162
APA Arıtuluk Aydın Z, Ozkul Kocak C, Renda G, EKİZOĞLU M, EZER N (2019). Antimicrobial activity of three Scutellaria L. species from Turkey. Journal of research in pharmacy (online), 23(3), 552 - 558. 10.12991/jrp.2019.162
Chicago Arıtuluk Aydın Zekiye Ceren,Ozkul Kocak Ceren,Renda Gülin,EKİZOĞLU Melike,EZER Nurten Antimicrobial activity of three Scutellaria L. species from Turkey. Journal of research in pharmacy (online) 23, no.3 (2019): 552 - 558. 10.12991/jrp.2019.162
MLA Arıtuluk Aydın Zekiye Ceren,Ozkul Kocak Ceren,Renda Gülin,EKİZOĞLU Melike,EZER Nurten Antimicrobial activity of three Scutellaria L. species from Turkey. Journal of research in pharmacy (online), vol.23, no.3, 2019, ss.552 - 558. 10.12991/jrp.2019.162
AMA Arıtuluk Aydın Z,Ozkul Kocak C,Renda G,EKİZOĞLU M,EZER N Antimicrobial activity of three Scutellaria L. species from Turkey. Journal of research in pharmacy (online). 2019; 23(3): 552 - 558. 10.12991/jrp.2019.162
Vancouver Arıtuluk Aydın Z,Ozkul Kocak C,Renda G,EKİZOĞLU M,EZER N Antimicrobial activity of three Scutellaria L. species from Turkey. Journal of research in pharmacy (online). 2019; 23(3): 552 - 558. 10.12991/jrp.2019.162
IEEE Arıtuluk Aydın Z,Ozkul Kocak C,Renda G,EKİZOĞLU M,EZER N "Antimicrobial activity of three Scutellaria L. species from Turkey." Journal of research in pharmacy (online), 23, ss.552 - 558, 2019. 10.12991/jrp.2019.162
ISNAD Arıtuluk Aydın, Zekiye Ceren vd. "Antimicrobial activity of three Scutellaria L. species from Turkey". Journal of research in pharmacy (online) 23/3 (2019), 552-558. https://doi.org/10.12991/jrp.2019.162
Sayfa Oluşturulma Tarihi
23-04-2024 13:19

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