Cryptotanshinone mitigates ischemia reperfusion-induced testicular damage: A experimental study

polat, elif; guler, mustafa can; topdağı, ömer; ERASLAN, Ersen; tanyeli, ayhan; Güzel Erdoğan, Derya; Ekinci Akdemir, Fazile Nur

doi:10.5455/annalsmedres.2019.09.535

Cryptotanshinone mitigates ischemia reperfusion-induced testicular damage: A experimental study

Ayhan TANYELİ, (Atatürk Üniversitesi, Tıp Fakültesi, Fizyoloji Anabilim Dalı, Erzurum, Türkiye)

Ersen ERASLAN, (Yozgat Bozok Üniversitesi, Tıp Fakültesi, Fizyoloji Anabilim Dalı, Yozgat, Türkiye)

Fazile Nur EKİNCİ AKDEMİR, (Ağrı İbrahim Çeçen Üniversitesi, Sağlık Yüksek Okulu, Beslenme ve Diyetetik Bölümü, Ağrı, Türkiye)

Mustafa CAN GÜLER, (Atatürk Üniversitesi, Tıp Fakültesi, Fizyoloji Anabilim Dalı, Erzurum, Türkiye)

Derya GÜZEL ERDOĞAN, (Sakarya Üniversitesi, Tıp Fakültesi, Fizyoloji Anabilim Dalı, Sakarya, Türkiye)

Elif POPALT, (Atatürk Üniversitesi, Tıp Fakültesi, Biyokimya Anabilim Dalı, Erzurum, Türkiye)

Ömer TOPDAĞI (Atatürk Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Erzurum, Türkiye)

Annals of Medical Research

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Yıl: 2019 Cilt: 26 Sayı: 11 Sayfa Aralığı: 2549 - 2552 Metin Dili: İngilizce DOI: 10.5455/annalsmedres.2019.09.535 İndeks Tarihi: 23-09-2020

Cryptotanshinone mitigates ischemia reperfusion-induced testicular damage: A experimental study

Öz:

Aim: The aim of this study is to investigate the protective effects of cryptotanshinone on ischemia reperfusion-induced testisdamage.Materials and Methods: In this study, the rats were divided into 3 groups. Groups of the study are planned as follows; sham, ischemiareperfusion, and ischemia reperfusion+cryptotanshinone. Oxidant molecules such as total oxidant status (TOS), malondialdehyde(MDA), myeloperoxidase (MPO) and antioxidant molecules like total antioxidant status (TAS), superoxide dismutase (SOD) withoxidative stress index (OSI) were evaluated in the testicular tissues obtained at the end of the experiment.Results: In ischemia reperfusion group, TAS and SOD levels decreased while other oxidant parameters were increased. But inischemia reperfusion+cryptotanshinone group, the levels of anti¬oxidant parameters increased while the levels of oxidant parametersdecreased.Conclusion: These results have shown us that cryptotanshinone is highly effective against oxidative testis damage caused byischemia reperfusion.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	tanyeli a, ERASLAN E, Ekinci Akdemir F, guler m, Güzel Erdoğan D, polat e, topdağı ö (2019). Cryptotanshinone mitigates ischemia reperfusion-induced testicular damage: A experimental study. , 2549 - 2552. 10.5455/annalsmedres.2019.09.535
Chicago	tanyeli ayhan,ERASLAN Ersen,Ekinci Akdemir Fazile Nur,guler mustafa can,Güzel Erdoğan Derya,polat elif,topdağı ömer Cryptotanshinone mitigates ischemia reperfusion-induced testicular damage: A experimental study. (2019): 2549 - 2552. 10.5455/annalsmedres.2019.09.535
MLA	tanyeli ayhan,ERASLAN Ersen,Ekinci Akdemir Fazile Nur,guler mustafa can,Güzel Erdoğan Derya,polat elif,topdağı ömer Cryptotanshinone mitigates ischemia reperfusion-induced testicular damage: A experimental study. , 2019, ss.2549 - 2552. 10.5455/annalsmedres.2019.09.535
AMA	tanyeli a,ERASLAN E,Ekinci Akdemir F,guler m,Güzel Erdoğan D,polat e,topdağı ö Cryptotanshinone mitigates ischemia reperfusion-induced testicular damage: A experimental study. . 2019; 2549 - 2552. 10.5455/annalsmedres.2019.09.535
Vancouver	tanyeli a,ERASLAN E,Ekinci Akdemir F,guler m,Güzel Erdoğan D,polat e,topdağı ö Cryptotanshinone mitigates ischemia reperfusion-induced testicular damage: A experimental study. . 2019; 2549 - 2552. 10.5455/annalsmedres.2019.09.535
IEEE	tanyeli a,ERASLAN E,Ekinci Akdemir F,guler m,Güzel Erdoğan D,polat e,topdağı ö "Cryptotanshinone mitigates ischemia reperfusion-induced testicular damage: A experimental study." , ss.2549 - 2552, 2019. 10.5455/annalsmedres.2019.09.535
ISNAD	tanyeli, ayhan vd. "Cryptotanshinone mitigates ischemia reperfusion-induced testicular damage: A experimental study". (2019), 2549-2552. https://doi.org/10.5455/annalsmedres.2019.09.535

APA	tanyeli a, ERASLAN E, Ekinci Akdemir F, guler m, Güzel Erdoğan D, polat e, topdağı ö (2019). Cryptotanshinone mitigates ischemia reperfusion-induced testicular damage: A experimental study. Annals of Medical Research, 26(11), 2549 - 2552. 10.5455/annalsmedres.2019.09.535
Chicago	tanyeli ayhan,ERASLAN Ersen,Ekinci Akdemir Fazile Nur,guler mustafa can,Güzel Erdoğan Derya,polat elif,topdağı ömer Cryptotanshinone mitigates ischemia reperfusion-induced testicular damage: A experimental study. Annals of Medical Research 26, no.11 (2019): 2549 - 2552. 10.5455/annalsmedres.2019.09.535
MLA	tanyeli ayhan,ERASLAN Ersen,Ekinci Akdemir Fazile Nur,guler mustafa can,Güzel Erdoğan Derya,polat elif,topdağı ömer Cryptotanshinone mitigates ischemia reperfusion-induced testicular damage: A experimental study. Annals of Medical Research, vol.26, no.11, 2019, ss.2549 - 2552. 10.5455/annalsmedres.2019.09.535
AMA	tanyeli a,ERASLAN E,Ekinci Akdemir F,guler m,Güzel Erdoğan D,polat e,topdağı ö Cryptotanshinone mitigates ischemia reperfusion-induced testicular damage: A experimental study. Annals of Medical Research. 2019; 26(11): 2549 - 2552. 10.5455/annalsmedres.2019.09.535
Vancouver	tanyeli a,ERASLAN E,Ekinci Akdemir F,guler m,Güzel Erdoğan D,polat e,topdağı ö Cryptotanshinone mitigates ischemia reperfusion-induced testicular damage: A experimental study. Annals of Medical Research. 2019; 26(11): 2549 - 2552. 10.5455/annalsmedres.2019.09.535
IEEE	tanyeli a,ERASLAN E,Ekinci Akdemir F,guler m,Güzel Erdoğan D,polat e,topdağı ö "Cryptotanshinone mitigates ischemia reperfusion-induced testicular damage: A experimental study." Annals of Medical Research, 26, ss.2549 - 2552, 2019. 10.5455/annalsmedres.2019.09.535
ISNAD	tanyeli, ayhan vd. "Cryptotanshinone mitigates ischemia reperfusion-induced testicular damage: A experimental study". Annals of Medical Research 26/11 (2019), 2549-2552. https://doi.org/10.5455/annalsmedres.2019.09.535