Comparison of surgery and surgery plus corticosteroid therapy in idiopathic granulomatous mastitis, prospective randomized study

Sözüer, Erdoğan Mütevelli; ÖZ, Bahadır; DOGAN, SERAP; ARIKAN, TURKMEN BAHADIR; AKCAN, ALPER CELAL; gün, iskender; patmano, mehmet

doi:10.5455/annalsmedres.2019.09.533

Comparison of surgery and surgery plus corticosteroid therapy in idiopathic granulomatous mastitis, prospective randomized study

Mehmet PATMANO, (Şanlıurfa Eğitim ve Öğretim Hastanesi, Genel Cerrahi Kliniği, Şanlıurfa, Türkiye)

Alper AKCAN, (Erciyes Üniversitesi, Tıp Fakültesi, Genel Cerrahi Anabilim Dalı, Kayseri, Türkiye)

Abdullah Bahadır ÖZ, (Erciyes Üniversitesi, Tıp Fakültesi, Genel Cerrahi Anabilim Dalı, Kayseri, Türkiye)

Türkmen Bahadır ARIKAN, (Erciyes Üniversitesi, Tıp Fakültesi, Genel Cerrahi Anabilim Dalı, Kayseri, Türkiye)

Serap DOĞAN, (Erciyes Üniversitesi, Tıp Fakültesi, Radyoloji Anabilim Dalı, Kayseri, Türkiye)

İskender GÜN, (ERCİYES ÜNİVERSİTESİ > TIP FAKÜLTESİ > DAHİLİ TIP BİLİMLERİ BÖLÜMÜ > HALK SAĞLIĞI ANABİLİM DALI)

Erdoğan SÖZÜER (Erciyes Üniversitesi, Tıp Fakültesi, Genel Cerrahi Anabilim Dalı, Kayseri, Türkiye)

Annals of Medical Research

1 0

Yıl: 2019 Cilt: 26 Sayı: 12 Sayfa Aralığı: 2984 - 2989 Metin Dili: İngilizce DOI: 10.5455/annalsmedres.2019.09.533 İndeks Tarihi: 29-09-2020

Comparison of surgery and surgery plus corticosteroid therapy in idiopathic granulomatous mastitis, prospective randomized study

Öz:

Aim: To compare therapeutic effectiveness of surgery alone with surgery plus corticosteroid in patients with granulomatous mastitis.Material and Methods: The study included 30 patients aged 23-60 years. The patients were randomly assigned into two groupsby lot. In-group 1, the patients received 375 mg ampicillin-sulbactam (twice daily, p.o.) for a week; than 32 mg prednisolone wasstarted which was gradually tapered (biweekly by 8 mg) over 8 weeks. Surgery was performed 2 weeks after tapering. In-group 2,the patients received 375 mg ampicillin-sulbactam (twice daily, p.o.) for a week and underwent surgery. During 2-years follow-up, allpatients were assessed for etiological factors and recurrence.Results: No significant differences was found in demographic characteristics, smoking habits, oral contraceptive use, presentingcomplaints, physical examination findings, localization and diagnostic tools used between groups. During follow-up, recurrencewas seen in one patient (6.7%) in surgery group and in 3 patients (20%) in steroid group but no significant difference was detectedbetween groups (p>0.05).Conclusion: In patients with granulomatous mastitis, systemic steroid therapy is an effective modality in patients unresponsive toantibiotic therapy after ruling out tuberculosis.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	patmano m, AKCAN A, ÖZ B, ARIKAN T, DOGAN S, gün i, Sözüer E (2019). Comparison of surgery and surgery plus corticosteroid therapy in idiopathic granulomatous mastitis, prospective randomized study. , 2984 - 2989. 10.5455/annalsmedres.2019.09.533
Chicago	patmano mehmet,AKCAN ALPER CELAL,ÖZ Bahadır,ARIKAN TURKMEN BAHADIR,DOGAN SERAP,gün iskender,Sözüer Erdoğan Mütevelli Comparison of surgery and surgery plus corticosteroid therapy in idiopathic granulomatous mastitis, prospective randomized study. (2019): 2984 - 2989. 10.5455/annalsmedres.2019.09.533
MLA	patmano mehmet,AKCAN ALPER CELAL,ÖZ Bahadır,ARIKAN TURKMEN BAHADIR,DOGAN SERAP,gün iskender,Sözüer Erdoğan Mütevelli Comparison of surgery and surgery plus corticosteroid therapy in idiopathic granulomatous mastitis, prospective randomized study. , 2019, ss.2984 - 2989. 10.5455/annalsmedres.2019.09.533
AMA	patmano m,AKCAN A,ÖZ B,ARIKAN T,DOGAN S,gün i,Sözüer E Comparison of surgery and surgery plus corticosteroid therapy in idiopathic granulomatous mastitis, prospective randomized study. . 2019; 2984 - 2989. 10.5455/annalsmedres.2019.09.533
Vancouver	patmano m,AKCAN A,ÖZ B,ARIKAN T,DOGAN S,gün i,Sözüer E Comparison of surgery and surgery plus corticosteroid therapy in idiopathic granulomatous mastitis, prospective randomized study. . 2019; 2984 - 2989. 10.5455/annalsmedres.2019.09.533
IEEE	patmano m,AKCAN A,ÖZ B,ARIKAN T,DOGAN S,gün i,Sözüer E "Comparison of surgery and surgery plus corticosteroid therapy in idiopathic granulomatous mastitis, prospective randomized study." , ss.2984 - 2989, 2019. 10.5455/annalsmedres.2019.09.533
ISNAD	patmano, mehmet vd. "Comparison of surgery and surgery plus corticosteroid therapy in idiopathic granulomatous mastitis, prospective randomized study". (2019), 2984-2989. https://doi.org/10.5455/annalsmedres.2019.09.533

APA	patmano m, AKCAN A, ÖZ B, ARIKAN T, DOGAN S, gün i, Sözüer E (2019). Comparison of surgery and surgery plus corticosteroid therapy in idiopathic granulomatous mastitis, prospective randomized study. Annals of Medical Research, 26(12), 2984 - 2989. 10.5455/annalsmedres.2019.09.533
Chicago	patmano mehmet,AKCAN ALPER CELAL,ÖZ Bahadır,ARIKAN TURKMEN BAHADIR,DOGAN SERAP,gün iskender,Sözüer Erdoğan Mütevelli Comparison of surgery and surgery plus corticosteroid therapy in idiopathic granulomatous mastitis, prospective randomized study. Annals of Medical Research 26, no.12 (2019): 2984 - 2989. 10.5455/annalsmedres.2019.09.533
MLA	patmano mehmet,AKCAN ALPER CELAL,ÖZ Bahadır,ARIKAN TURKMEN BAHADIR,DOGAN SERAP,gün iskender,Sözüer Erdoğan Mütevelli Comparison of surgery and surgery plus corticosteroid therapy in idiopathic granulomatous mastitis, prospective randomized study. Annals of Medical Research, vol.26, no.12, 2019, ss.2984 - 2989. 10.5455/annalsmedres.2019.09.533
AMA	patmano m,AKCAN A,ÖZ B,ARIKAN T,DOGAN S,gün i,Sözüer E Comparison of surgery and surgery plus corticosteroid therapy in idiopathic granulomatous mastitis, prospective randomized study. Annals of Medical Research. 2019; 26(12): 2984 - 2989. 10.5455/annalsmedres.2019.09.533
Vancouver	patmano m,AKCAN A,ÖZ B,ARIKAN T,DOGAN S,gün i,Sözüer E Comparison of surgery and surgery plus corticosteroid therapy in idiopathic granulomatous mastitis, prospective randomized study. Annals of Medical Research. 2019; 26(12): 2984 - 2989. 10.5455/annalsmedres.2019.09.533
IEEE	patmano m,AKCAN A,ÖZ B,ARIKAN T,DOGAN S,gün i,Sözüer E "Comparison of surgery and surgery plus corticosteroid therapy in idiopathic granulomatous mastitis, prospective randomized study." Annals of Medical Research, 26, ss.2984 - 2989, 2019. 10.5455/annalsmedres.2019.09.533
ISNAD	patmano, mehmet vd. "Comparison of surgery and surgery plus corticosteroid therapy in idiopathic granulomatous mastitis, prospective randomized study". Annals of Medical Research 26/12 (2019), 2984-2989. https://doi.org/10.5455/annalsmedres.2019.09.533