TY  - JOUR
TI  - Comparison of surgery and surgery plus corticosteroid therapy in idiopathic granulomatous mastitis, prospective randomized study
AB  - Aim: To compare therapeutic effectiveness of surgery alone with surgery plus corticosteroid in patients with granulomatous mastitis.Material and Methods: The study included 30 patients aged 23-60 years. The patients were randomly assigned into two groupsby lot. In-group 1, the patients received 375 mg ampicillin-sulbactam (twice daily, p.o.) for a week; than 32 mg prednisolone wasstarted which was gradually tapered (biweekly by 8 mg) over 8 weeks. Surgery was performed 2 weeks after tapering. In-group 2,the patients received 375 mg ampicillin-sulbactam (twice daily, p.o.) for a week and underwent surgery. During 2-years follow-up, allpatients were assessed for etiological factors and recurrence.Results: No significant differences was found in demographic characteristics, smoking habits, oral contraceptive use, presentingcomplaints, physical examination findings, localization and diagnostic tools used between groups. During follow-up, recurrencewas seen in one patient (6.7%) in surgery group and in 3 patients (20%) in steroid group but no significant difference was detectedbetween groups (p>0.05).Conclusion: In patients with granulomatous mastitis, systemic steroid therapy is an effective modality in patients unresponsive toantibiotic therapy after ruling out tuberculosis.
AU  - Sözüer, Erdoğan Mütevelli
AU  - ÖZ, Bahadır
AU  - DOGAN, SERAP
AU  - ARIKAN, TURKMEN BAHADIR
AU  - AKCAN, ALPER CELAL
AU  - gün, iskender
AU  - patmano, mehmet
DO  - 10.5455/annalsmedres.2019.09.533
PY  - 2019
JO  - Annals of Medical Research
VL  - 26
IS  - 12
SN  - 2636-7688
SP  - 2984
EP  - 2989
DB  - TRDizin
UR  - http://search/yayin/detay/359228
ER  -