Is There Any Relation Between Recurrent Miscarriage and Complete Blood Count Values? A Case-Control Study

koşan, zahide; Cayir, Yasemin; ERDEM, Haktan Bagis; SEVER ERDEM, Zeynep

doi:10.18521/ktd.518494

Is There Any Relation Between Recurrent Miscarriage and Complete Blood Count Values? A Case-Control Study

Zeynep SEVER ERDEM, (Pamuklar Aile Sağlığı Merkezi, Yenimahalle, Ankara, Türkiye)

Yasemin ÇAYIR, (Atatürk Üniversitesi, Tıp Fakültesi, Aile Bölümü, Erzurum, Türkiye)

Zahide KOŞAN, (Atatürk Üniversitesi, Tıp Fakültesi, Halk Sağlığı Anabilim Dalı, Erzurum, Türkiye)

Haktan ERDEM (Dışkapı Yıldırım Beyazıt Araştırma ve Eğitim Hastanesi, Tıp Bölümü Genetik, Ankara, Türkiye)

KONURALP TIP DERGİSİ

29 3

Yıl: 2020 Cilt: 12 Sayı: 1 Sayfa Aralığı: 39 - 43 Metin Dili: İngilizce DOI: 10.18521/ktd.518494 İndeks Tarihi: 12-10-2020

Is There Any Relation Between Recurrent Miscarriage and Complete Blood Count Values? A Case-Control Study

Öz:

Objective: It was aimed to examine the relationship of complete blood count valueswith recurrent miscarriage.Methods: We carried out a case-control study of patients who had recurrent miscarriagebetween 2010-2018. Data were collected from 50 patients who were meeting the casegroup inclusion criteria, and age-matched healthy control group with at least one livebirth who consisted of 60 women. Red blood cell (RBC), hemoglobin (HB), hematocrit(HTC), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), meancorpuscular hemoglobin concentration (MCHC), platelet count (PLT), plateletdistribution width (PDW), mean platelet volume (MPV), red cell distribution width(RDW) and plateletcrit count (PCT) were examined by complete blood count. SPSS20.0.0 software was used for statistical analysis. P values <0.05 were regarded asstatistically significant.Results: The mean age of the case group was 29.8±5.8 years, and the mean age of thecontrol group was 28.7±5.2 years (p>0,05). MPV and RDW values and PCT calculationswere significantly higher than healthy control group (p<0.05). MCHC levels of casegroup were lower than control group (p<0.05). There were no significant differencesbetween the case and control groups in terms of RBC, HB, HCT, MCV, MCH, PLT, andPDW (p>0.05).Conclusions: Complete blood count parameters such as high MPV, RDW, PCT, andlow MCHC could be considered as an important predictor of recurrent miscarriage. Ourfindings should be supported by further prospective studies involving a larger number ofpatients in order to clarify the relationship between these blood cell function markers andrecurrent miscarriage.

Anahtar Kelime:

Tekrarlayan Düşük Ve Tam Kan Sayımı Değerleri Arasında Herhangi Bir İlişki Var Mı? Bir Vaka-Kontrol Çalışması

Öz:

Amaç: Tam kan sayımı değerleri ile tekrarlayan düşük arasındaki ilişkinin incelenmesi amaçlanmıştır. Gereç ve Yöntem: 2010-2018 yılları arasında tekrarlayan düşük yapan hastalarda vakakontrol çalışması yaptık. Vaka grubunda dahil edilme kriterlerini karşılayan 50 hastanın verilerini, 60 kadından oluşan, en az bir canlı doğum yapmış aynı yaş grubundan kontrol grubu ile eşleştirdik. Tam kan sayımında kırmızı kan hücresi (RBC), hemoglobin (HB), hematokrit (HTC), ortalama korpüsküler hacim (MCV), ortalama korpüsküler hemoglobin (MCH), ortalama korpüsküler hemoglobin konsantrasyonu (MCHC), trombosit sayısı (PLT), trombosit dağılım genişliği (PDW), kan sayımında ortalama trombosit hacmi (MPV), kırmızı hücre dağılım genişliği (RDW) ve plateletkreit hesaplaması (PCT) incelendi. İstatistiksel analiz için SPSS 20.0.0 yazılımı kullanıldı. P<0,05 değeri istatistiksel olarak anlamlı kabul edildi. Bulgular: Kontrol grubunun yaş ortalaması 28,7±5,2 yıl iken; vaka grubununki 29,8±5,8 yıldı (p>0,05). Vaka grubunda MPV ve RDW değerleri ile PCT hesaplaması sağlıklı kontrol grubundan anlamlı olarak yüksek bulundu (p<0,05). Vaka grubunun MCHC düzeyleri kontrol grubundan düşüktü (p<0,05). Vaka ve kontrol grubu arasında RBC, HB, HCT, MCV, MCH, PLT ve PDW açısından anlamlı bir fark yoktu (p>0,05). Sonuç: Yüksek MPV, RDW, PCT ve düşük MCHC gibi tam kan sayımı parametreleri, tekrarlayan düşüklerin önemli bir belirleyicisi olarak düşünülebilir. Bulgularımız, bu kan hücresi fonksiyon belirteçleri ve tekrarlayan düşükler arasındaki ilişkiyi netleştirmek için daha fazla sayıda hasta içeren ileriye dönük çalışmalar ile desteklenmelidir.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	SEVER ERDEM Z, Cayir Y, koşan z, ERDEM H (2020). Is There Any Relation Between Recurrent Miscarriage and Complete Blood Count Values? A Case-Control Study. , 39 - 43. 10.18521/ktd.518494
Chicago	SEVER ERDEM Zeynep,Cayir Yasemin,koşan zahide,ERDEM Haktan Bagis Is There Any Relation Between Recurrent Miscarriage and Complete Blood Count Values? A Case-Control Study. (2020): 39 - 43. 10.18521/ktd.518494
MLA	SEVER ERDEM Zeynep,Cayir Yasemin,koşan zahide,ERDEM Haktan Bagis Is There Any Relation Between Recurrent Miscarriage and Complete Blood Count Values? A Case-Control Study. , 2020, ss.39 - 43. 10.18521/ktd.518494
AMA	SEVER ERDEM Z,Cayir Y,koşan z,ERDEM H Is There Any Relation Between Recurrent Miscarriage and Complete Blood Count Values? A Case-Control Study. . 2020; 39 - 43. 10.18521/ktd.518494
Vancouver	SEVER ERDEM Z,Cayir Y,koşan z,ERDEM H Is There Any Relation Between Recurrent Miscarriage and Complete Blood Count Values? A Case-Control Study. . 2020; 39 - 43. 10.18521/ktd.518494
IEEE	SEVER ERDEM Z,Cayir Y,koşan z,ERDEM H "Is There Any Relation Between Recurrent Miscarriage and Complete Blood Count Values? A Case-Control Study." , ss.39 - 43, 2020. 10.18521/ktd.518494
ISNAD	SEVER ERDEM, Zeynep vd. "Is There Any Relation Between Recurrent Miscarriage and Complete Blood Count Values? A Case-Control Study". (2020), 39-43. https://doi.org/10.18521/ktd.518494

APA	SEVER ERDEM Z, Cayir Y, koşan z, ERDEM H (2020). Is There Any Relation Between Recurrent Miscarriage and Complete Blood Count Values? A Case-Control Study. KONURALP TIP DERGİSİ, 12(1), 39 - 43. 10.18521/ktd.518494
Chicago	SEVER ERDEM Zeynep,Cayir Yasemin,koşan zahide,ERDEM Haktan Bagis Is There Any Relation Between Recurrent Miscarriage and Complete Blood Count Values? A Case-Control Study. KONURALP TIP DERGİSİ 12, no.1 (2020): 39 - 43. 10.18521/ktd.518494
MLA	SEVER ERDEM Zeynep,Cayir Yasemin,koşan zahide,ERDEM Haktan Bagis Is There Any Relation Between Recurrent Miscarriage and Complete Blood Count Values? A Case-Control Study. KONURALP TIP DERGİSİ, vol.12, no.1, 2020, ss.39 - 43. 10.18521/ktd.518494
AMA	SEVER ERDEM Z,Cayir Y,koşan z,ERDEM H Is There Any Relation Between Recurrent Miscarriage and Complete Blood Count Values? A Case-Control Study. KONURALP TIP DERGİSİ. 2020; 12(1): 39 - 43. 10.18521/ktd.518494
Vancouver	SEVER ERDEM Z,Cayir Y,koşan z,ERDEM H Is There Any Relation Between Recurrent Miscarriage and Complete Blood Count Values? A Case-Control Study. KONURALP TIP DERGİSİ. 2020; 12(1): 39 - 43. 10.18521/ktd.518494
IEEE	SEVER ERDEM Z,Cayir Y,koşan z,ERDEM H "Is There Any Relation Between Recurrent Miscarriage and Complete Blood Count Values? A Case-Control Study." KONURALP TIP DERGİSİ, 12, ss.39 - 43, 2020. 10.18521/ktd.518494
ISNAD	SEVER ERDEM, Zeynep vd. "Is There Any Relation Between Recurrent Miscarriage and Complete Blood Count Values? A Case-Control Study". KONURALP TIP DERGİSİ 12/1 (2020), 39-43. https://doi.org/10.18521/ktd.518494