Yıl: 2020 Cilt: 27 Sayı: 1 Sayfa Aralığı: 116 - 121 Metin Dili: İngilizce DOI: 10.5455/annalsmedres.2019.11.746 İndeks Tarihi: 12-10-2020

Dual energy CT based iodine density in relation to histological parameters in gastric cancer

Öz:
Aim: To evaluate whether iodine density (ID) and normalized iodine density (NID) of tumor on rapid kV-switching dual energy CT isassociated with histological parameters which influences disease prognosis in gastric cancerMaterial and Methods: Twenty patients with gastric adenocarcinoma who had preoperative staging CT imaging dual energy modein arterial phase were retrospectively included. Patients who had neoadjuvant treatment prior to surgery were excluded. ID and NIDvalues were measured on arterial phase dual energy CT images on a dedicated workstation.Results: ID and NID of the tumor were significantly lower in poorly differentiated tumors compared with well differentiated tumors(p=0.019, p=0.046), and also in patients with unfavorable histology compared with unfavorable histology group (p=0.005, p=0.042).There were no significant ID and NID value differences between patients with and without serosal infiltration, nodal metastasis,lymphovascular and perineural invasion, surgical margin involvement (p>0.05).Conclusion: ID related parameters can be useful for predicting the prognosis of gastric cancer.
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  • 1. Rawla P, Barsouk A. Epidemiology of gastric cancer: global trends, risk factors and prevention. Prz Gastroenterol 2019;14:26-38.
  • 2. Ahn HS, Kim SH, Kodera Y, et al. Gastric cancer staging with radiologic imaging modalities and UICC staging system. Dig Surg 2013;30:142-9.
  • 3. Sun RJ, Tang L, Chen Y, et al. Feasibility of differentiating T3 from T4a gastric cancer in different Lauren classification by determining serosa invasion: Diagnostic performance of high enhanced serosa sign. Chin J Cancer Res 2018;30:263-71.
  • 4. Kwee RM, Kwee TC. Imaging in assessing lymph node status in gastric cancer. Gastric Cancer 2009;12:6-22.
  • 5. Dobritoiu M, Stepan AE, Vere CC, et al. Evaluation of Gastric Carcinomas Histological Patterns in Relation to Tumors Aggressiveness Parameters. Curr Health Sci J 2018;44:342-6.
  • 6. Luu C, Thapa R, Woo K, et al. Does histology really influence gastric cancer prognosis? J Gastrointest Oncol 2017;8:1026-36.
  • 7. McCollough CH, Leng S, Yu L, et al. Dual- and Multienergy ct: principles, technical approaches, and clinical applications. Radiology 2015;276:637-53.
  • 8. Agrawal MD, Pinho DF, Kulkarni NM, et al. Oncologic applications of dual-energy CT in the abdomen. Radiographics 2014;34:589-612.
  • 9. Meng X, Ni C, Shen Y, et al. Differentiating malignant from benign gastric mucosal lesions with quantitative analysis in dual energy spectral computed tomography: Initial experience. Medicine (Baltimore) 2017;96:e5878.
  • 10. Cheng SM, Ling W, Zhu J, et al. Dual energy spectral ct imaging in the assessment of gastric cancer and cell proliferation: a preliminary study. Sci Rep 2018;8:17619.
  • 11. Li J, Fang M, Wang R, et al. Diagnostic accuracy of dual-energy CT-based nomograms to predict lymph node metastasis in gastric cancer. Eur Radiol 2018;28:5241-9.
  • 12. Pan Z, Pang L, Ding B, et al. Gastric cancer staging with dual energy spectral CT imaging. PLoS One 2013;8:e53651.
  • 13. Yang L, Shi G, Zhou T, et al. Quantification of the iodine content of perigastric adipose tissue by dual-energy ct: a novel method for preoperative diagnosis of T4- stage gastric cancer. PLoS One 2015;10:e0136871.
  • 14. Kupeli A, Bulut E, Cansu A, et al. Contribution of DECT in detecting serosal invasion of gastric cancer. Turk J Med Sci 2019;49:782-8.
  • 15. Li R, Li J, Wang X, et al. Detection of gastric cancer and its histological type based on iodine concentration in spectral CT. Cancer Imaging 2018;18:42.
  • 16. Liang P, Ren XC, Gao JB, et al. Iodine Concentration in Spectral CT: Assessment of Prognostic Determinants in Patients With Gastric Adenocarcinoma. AJR Am J Roentgenol 2017;209:1033-8.
  • 17. Chen XH, Ren K, Liang P, et al. Spectral computed tomography in advanced gastric cancer: Can iodine concentration non-invasively assess angiogenesis? World J Gastroenterol. 2017;23:1666-75.
  • 18. Xie ZY, Chai RM, Ding GC, et al. T and N Staging of Gastric Cancer Using Dual-Source Computed Tomography. Gastroenterol Res Pract 2018;2018:5015202.
  • 19. Gabelloni M FL, Neri E. Imaging biomarkers in upper gastrointestinal cancers. BJR Open 2019;1(20190001).
  • 20. Marin D, Boll DT, Mileto A, et al. State of the art: dualenergy CT of the abdomen. Radiology. 2014;271:327- 42.
  • 21. Jacobsen MC, Schellingerhout D, Wood CA, et al. Intermanufacturer comparison of dual-energy ct iodine quantification and monochromatic attenuation: a phantom study. Radiology 2018;287:224-34.
  • 22. Rizzo S, Radice D, Femia M, et al. Metastatic and nonmetastatic lymph nodes: quantification and different distribution of iodine uptake assessed by dual-energy CT. Eur Radiol 2018;28:760-9.
  • 23. Li L, Zhao Y, Luo D, et al. Diagnostic value of single source dual-energy spectral computed tomography in differentiating parotid gland tumors: initial results. Quant Imaging Med Surg 2018;8:588-96.
  • 24. Gonzalez-Perez V, Arana E, Barrios M, et al. Differentiation of benign and malignant lung lesions: Dual-Energy Computed Tomography findings. Eur J Radiol 2016;85:1765-72.
  • 25. Chang Y, Niu W, Lian PL, et al. Endocan-expressing microvessel density as a prognostic factor for survival in human gastric cancer. World J Gastroenterol 2016;22:5422-9.
  • 26. Du JR, Jiang Y, Zhang YM, et al. Vascular endothelial growth factor and microvascular density in esophageal and gastric carcinomas. World J Gastroenterol 2003;9:1604-6.
  • 27. Kaza RK, Caoili EM, Cohan RH, et al. Distinguishing enhancing from nonenhancing renal lesions with fast kilovoltage-switching dual-energy CT. AJR Am J Roentgenol 2011;197:1375-81.
  • 28. Mileto A, Marin D, Alfaro-Cordoba M, et al. Iodine quantification to distinguish clear cell from papillary renal cell carcinoma at dual-energy multidetector CT: a multireader diagnostic performance study. Radiology 2014;273:813-20.
  • 29. Patel BN, Vernuccio F, Meyer M, et al. Dual-Energy CT Material Density Iodine Quantification for Distinguishing Vascular From Nonvascular Renal Lesions: Normalization Reduces Intermanufacturer Threshold Variability. AJR Am J Roentgenol 2019;212:366-76.
APA Çamlıdağ i (2020). Dual energy CT based iodine density in relation to histological parameters in gastric cancer. , 116 - 121. 10.5455/annalsmedres.2019.11.746
Chicago Çamlıdağ ilkay Dual energy CT based iodine density in relation to histological parameters in gastric cancer. (2020): 116 - 121. 10.5455/annalsmedres.2019.11.746
MLA Çamlıdağ ilkay Dual energy CT based iodine density in relation to histological parameters in gastric cancer. , 2020, ss.116 - 121. 10.5455/annalsmedres.2019.11.746
AMA Çamlıdağ i Dual energy CT based iodine density in relation to histological parameters in gastric cancer. . 2020; 116 - 121. 10.5455/annalsmedres.2019.11.746
Vancouver Çamlıdağ i Dual energy CT based iodine density in relation to histological parameters in gastric cancer. . 2020; 116 - 121. 10.5455/annalsmedres.2019.11.746
IEEE Çamlıdağ i "Dual energy CT based iodine density in relation to histological parameters in gastric cancer." , ss.116 - 121, 2020. 10.5455/annalsmedres.2019.11.746
ISNAD Çamlıdağ, ilkay. "Dual energy CT based iodine density in relation to histological parameters in gastric cancer". (2020), 116-121. https://doi.org/10.5455/annalsmedres.2019.11.746
APA Çamlıdağ i (2020). Dual energy CT based iodine density in relation to histological parameters in gastric cancer. Annals of Medical Research, 27(1), 116 - 121. 10.5455/annalsmedres.2019.11.746
Chicago Çamlıdağ ilkay Dual energy CT based iodine density in relation to histological parameters in gastric cancer. Annals of Medical Research 27, no.1 (2020): 116 - 121. 10.5455/annalsmedres.2019.11.746
MLA Çamlıdağ ilkay Dual energy CT based iodine density in relation to histological parameters in gastric cancer. Annals of Medical Research, vol.27, no.1, 2020, ss.116 - 121. 10.5455/annalsmedres.2019.11.746
AMA Çamlıdağ i Dual energy CT based iodine density in relation to histological parameters in gastric cancer. Annals of Medical Research. 2020; 27(1): 116 - 121. 10.5455/annalsmedres.2019.11.746
Vancouver Çamlıdağ i Dual energy CT based iodine density in relation to histological parameters in gastric cancer. Annals of Medical Research. 2020; 27(1): 116 - 121. 10.5455/annalsmedres.2019.11.746
IEEE Çamlıdağ i "Dual energy CT based iodine density in relation to histological parameters in gastric cancer." Annals of Medical Research, 27, ss.116 - 121, 2020. 10.5455/annalsmedres.2019.11.746
ISNAD Çamlıdağ, ilkay. "Dual energy CT based iodine density in relation to histological parameters in gastric cancer". Annals of Medical Research 27/1 (2020), 116-121. https://doi.org/10.5455/annalsmedres.2019.11.746