Yıl: 2020 Cilt: 21 Sayı: 2 Sayfa Aralığı: 70 - 78 Metin Dili: İngilizce

Testis spectroscopy may predict sperm retrieval rate in men with non-obstructive azoospermia undergoing micro-TESE: A pilot study

Öz:
Objective: To investigate whether prior testis magnetic resonance spectroscopy predicts the success or failure of micro-dissection testicularsperm extraction (micro-TESE) in patients with non-obstructive azoospermia (NOA).Material and Methods: Nine men with NOA who were scheduled for micro-TESE for the first time, 9 NOA men with a history of previousmicro-TESE and 5 fertile men were enrolled. All NOA patients and fertile controls underwent testis spectroscopy. A multi-voxel spectroscopysequence was used. Testicular signals of choline (Cho), creatine (Cr), myo-inositol (MI), lactate, and lipids were analyzed quantitatively andcompared with the results of the micro-TESEs.Results: The most prominent peaks were Cho and Cr in the fertile controls and NOA subjects with positive sperm retrieval in the micro-TESE. Ahigh Cho peak was detected in 87% of the NOA men with positive sperm retrieval. NOA men without sperm at the previous micro-TESE showeda marked decrease in Cho and Cr signals. For positive sperm retrieval in micro-TESE, the cut-off value of Cho was 1.46 ppm, the cut-off value ofCr was 1.43 ppm, and the cut-off value of MI was 0.79 ppm.Conclusion: Testis spectroscopy can be used as a non-invasive screening method to predict the success or failure of micro-TESE. (J Turk GerGynecol Assoc 2020; 21: 70-8)
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Konular:
Fen > Tıp > Kadın Hastalıkları ve Doğum
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA ÇELİK Ö, HATIRNAZ Ş, ERŞAHİN A, BAŞBUĞ A, YILDIRIM G, ÖZENER V, GÜRPINAR N, ÇELİK S, ÇELİK N, KÜÇÜK T, ÜNLÜ C (2020). Testis spectroscopy may predict sperm retrieval rate in men with non-obstructive azoospermia undergoing micro-TESE: A pilot study. Journal of the Turkish-German Gynecological Association, 21(2), 70 - 78.
Chicago ÇELİK Önder,HATIRNAZ Şafak,ERŞAHİN Aynur,BAŞBUĞ Alper,YILDIRIM Gonca Yetkin,ÖZENER Vahit,GÜRPINAR Neslihan,ÇELİK Sudenaz,ÇELİK Nilüfer,KÜÇÜK Tansu,ÜNLÜ Cihat Testis spectroscopy may predict sperm retrieval rate in men with non-obstructive azoospermia undergoing micro-TESE: A pilot study. Journal of the Turkish-German Gynecological Association 21, no.2 (2020): 70 - 78.
MLA ÇELİK Önder,HATIRNAZ Şafak,ERŞAHİN Aynur,BAŞBUĞ Alper,YILDIRIM Gonca Yetkin,ÖZENER Vahit,GÜRPINAR Neslihan,ÇELİK Sudenaz,ÇELİK Nilüfer,KÜÇÜK Tansu,ÜNLÜ Cihat Testis spectroscopy may predict sperm retrieval rate in men with non-obstructive azoospermia undergoing micro-TESE: A pilot study. Journal of the Turkish-German Gynecological Association, vol.21, no.2, 2020, ss.70 - 78.
AMA ÇELİK Ö,HATIRNAZ Ş,ERŞAHİN A,BAŞBUĞ A,YILDIRIM G,ÖZENER V,GÜRPINAR N,ÇELİK S,ÇELİK N,KÜÇÜK T,ÜNLÜ C Testis spectroscopy may predict sperm retrieval rate in men with non-obstructive azoospermia undergoing micro-TESE: A pilot study. Journal of the Turkish-German Gynecological Association. 2020; 21(2): 70 - 78.
Vancouver ÇELİK Ö,HATIRNAZ Ş,ERŞAHİN A,BAŞBUĞ A,YILDIRIM G,ÖZENER V,GÜRPINAR N,ÇELİK S,ÇELİK N,KÜÇÜK T,ÜNLÜ C Testis spectroscopy may predict sperm retrieval rate in men with non-obstructive azoospermia undergoing micro-TESE: A pilot study. Journal of the Turkish-German Gynecological Association. 2020; 21(2): 70 - 78.
IEEE ÇELİK Ö,HATIRNAZ Ş,ERŞAHİN A,BAŞBUĞ A,YILDIRIM G,ÖZENER V,GÜRPINAR N,ÇELİK S,ÇELİK N,KÜÇÜK T,ÜNLÜ C "Testis spectroscopy may predict sperm retrieval rate in men with non-obstructive azoospermia undergoing micro-TESE: A pilot study." Journal of the Turkish-German Gynecological Association, 21, ss.70 - 78, 2020.