TY  - JOUR
TI  - Testis spectroscopy may predict sperm retrieval rate in men with non-obstructive azoospermia undergoing micro-TESE: A pilot study
AB  - Objective: To investigate whether prior testis magnetic resonance spectroscopy predicts the success or failure of micro-dissection testicularsperm extraction (micro-TESE) in patients with non-obstructive azoospermia (NOA).Material and Methods: Nine men with NOA who were scheduled for micro-TESE for the first time, 9 NOA men with a history of previousmicro-TESE and 5 fertile men were enrolled. All NOA patients and fertile controls underwent testis spectroscopy. A multi-voxel spectroscopysequence was used. Testicular signals of choline (Cho), creatine (Cr), myo-inositol (MI), lactate, and lipids were analyzed quantitatively andcompared with the results of the micro-TESEs.Results: The most prominent peaks were Cho and Cr in the fertile controls and NOA subjects with positive sperm retrieval in the micro-TESE. Ahigh Cho peak was detected in 87% of the NOA men with positive sperm retrieval. NOA men without sperm at the previous micro-TESE showeda marked decrease in Cho and Cr signals. For positive sperm retrieval in micro-TESE, the cut-off value of Cho was 1.46 ppm, the cut-off value ofCr was 1.43 ppm, and the cut-off value of MI was 0.79 ppm.Conclusion: Testis spectroscopy can be used as a non-invasive screening method to predict the success or failure of micro-TESE. (J Turk GerGynecol Assoc 2020; 21: 70-8)
AU  - Ünlü, Mehmet Cihat
AU  - GÜRPINAR, Neslihan
AU  - ersahin, aynur
AU  - hatirnaz, safak
AU  - yetkin yildirim, gonca
AU  - Celik, Önder
AU  - ÖZENER, Vahit
AU  - celik, nilufer
AU  - KÜÇÜK, Tansu
AU  - basbug, alper
AU  - ÇELİK, Sudenaz
PY  - 2020
JO  - Journal of the Turkish-German Gynecological Association
VL  - 21
IS  - 2
SN  - 1309-0399
SP  - 70
EP  - 78
DB  - TRDizin
UR  - http://search/yayin/detay/364837
ER  -