Association of sexual function and psychological symptoms including depression, anxiety and stress in women with recurrent vulvovaginal candidiasis

Moshfeghy, Zeinab; Mani, Arash; sayadi, mehrab; Tahari, Somayeh; Janghorban, Roksana; NAJIB, Fatemeh Sadat

Association of sexual function and psychological symptoms including depression, anxiety and stress in women with recurrent vulvovaginal candidiasis

Zeinab MOSHFEGHY, (Shahid Beheshti University of Medical Sciences, Tehran, Iran)

Somayeh TAHARI, (Shiraz University of Medical Sciences, Shiraz, Iran)

Roksana JANGHORBAN, (Shiraz University of Medical Sciences, Shiraz, Iran)

Fatemeh Sadat NAJIB, (Shiraz University of Medical Sciences, Shiraz, Iran)

Arash MANI, (Shiraz University of Medical Sciences, Shiraz, Iran)

Mehrab SAYADI (Shiraz University of Medical Sciences, Shiraz, Iran)

Journal of the Turkish-German Gynecological Association

2 0

Yıl: 2020 Cilt: 21 Sayı: 2 Sayfa Aralığı: 90 - 96 Metin Dili: İngilizce İndeks Tarihi: 16-10-2020

Association of sexual function and psychological symptoms including depression, anxiety and stress in women with recurrent vulvovaginal candidiasis

Öz:

Objective: Recurrent vulvovaginal candidiasis (RVVC) is a common vaginal infection which could affect the quality of life, romantic relationships,and sexual performance. There is some evidence that psychological problems result in an increased incidence of RVVC by changing the immunesystems of individuals. The aim of this study was to determine the association of sexual function and psychological factors including depression,anxiety, and stress in women with RVVC.Material and Methods: Study design was case controlled. Equal numbers of women with RVVC and uninfected women referred to gynecologyclinics were selected, using convenience purposive sampling. Two samples of vaginal discharge were prepared from each person. One samplewas examined microscopically and the second was cultured on Sabouraud Agar. Data collection tools used for this study included demographicquestionnaire, Female Sexual Function Index, Depression Anxiety Stress Scales-21. Data were analyzed using SPSS software (version 19).Results: Less sexual satisfaction [odds ratio (OR): 0.608, 95% confidence interval (CI): 0.421-0.878] and less orgasm (OR: 0.741, 95% CI: 0.530-0.998) was associated with RVVC. In patients with RVVC, the levels of depression, anxiety and stress were significantly higher compared to thoseof healthy individuals.Conclusion: Depression, anxiety and stress in the past four weeks are related to an increased risk of RVVC. There is an association betweendepression, anxiety and stress, sexual satisfaction, and orgasm with RVVC. It may be that psychological interventions and sexual counseling canbe effective in improving RVVC. (J Turk Ger Gynecol Assoc 2020; 21: 90-6)

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World Health Organization. Global health sector strategy on Sexually Transmitted Infections 2016-2021. 2016.
Gil NF, Martinez RCR, Gomes BC, Nomizo A, Martinis ECPD. Vaginal lactobacilli as potential probiotics against Candida spp. Braz J Microbiol 2010; 41: 6-14.
Hainer LB, Gibson MV. Vaginitis: Diagnosis and treatment. Am Fam Physician 2011; 83: 807-15.
Berek JS. Bereks and Novak’s Gynecology. Lippincott Williams and Wilkins. Philadelphia; 2012.
Zhu YX, Li T, Fan SR, Liu XP, Liang YH, Liu P. Health-related quality of life as measured with the Short-Form 36 (SF-36) questionnaire in patients with recurrent vulvovaginal candidiasis. Health Qual Life Outcomes 2016; 14: 65.
Ekpenyong CE, Inyang-etoh EC, Ettebong EO, Akpan UP, Ibu JO, Daniel NE. Recurrent vulvovaginal candidosis among young women in south eastern Nigeria: the role of lifestyle and healthcare practices. Int J STD AIDS 2012; 23: 704-9.
Akbarzadeh M, Bonyadpour B, Pakshir K, Mohagheghzadeh A. Causes and clinical symptoms of vaginal candidiasis in patients referring to selective clinics of Shiraz University of Medical Sciences (2009). J Arak Uni Med Sci 2010; 13: 12-20.
Gunther LS, Martins HP, Gimenes F, Abreu AL, Consolaro ME, Svidzinski TI. Prevalence of Candida albicans and non-albicans isolates from vaginal secretions: comparative evaluation of colonization, vaginal candidiasis and recurrent vaginal candidiasis in diabetic and non-diabetic women. Sao Paulo Med J 2014; 132: 116-20.
Roozbahani F, Kariman N, Mojab F, Nasiri M. Effect of Myrtus communis capsule on vaginal candidiasis treatment. Pajoohandeh J 2013; 18: 242-9.
Emeribe AU, Nasir IA, Onyia J, Ifunanya Al. Prevalence of vulvovaginal candidiasis among nonpregnant women attending a tertiary health care facility in Abuja, Nigeria. Res Rep Trop Med 2015; 6: 37-42.
Esim BE, Kars B, Karsidag AY, Karadeniz BI, Kaymaz O, Gencer S, et al. Diagnosis of vulvovaginitis: Comparison of clinical and microbiological diagnosis. Arch Gynecol Obstet 2010; 282: 515-9.
Onianwah IF. The Incidence and Prevalence of Candida albicans infection of the urogenital tract of females between the ages of 18 and 45 years old: A Case study of Patients receiving treatment in Ashford and Patrice clinic in Port Harcourt. Int Res J Environment Sci 2014; 3: 101-4.
Foxman B, Ryan Muraglia, Dietz JP, Sobel JD, Wagner J. Prevalence of recurrent vulvovaginal candidiasis in 5 european countries and the united states: Results from an internet panel survey. J Low Genit Tract Dis 2013; 17: 340-5.
Weissenbacher T, Witkin S, Ledger W, Tolbert V, Gingelmaier A, Scholz C, et al. Relationship between clinical diagnosis of recurrent vulvovaginal candidiasis and detection of Candida species by culture and polymerase chain reaction. Arch Gynecol Obstet 2009; 279: 125-9.
Hedayati MT, Taheri Z, Galinimoghadam T, Aghili SR, Yazdani Cherati J, Mosayebi E. Isolation of different species of candida in patients with vulvovaginal candidiasis from Sari, Iran. Jundishapur J Microbiol 2015; 8: e15992.
Ehrström S, Kornfeld D, Thuresson J, Rylander E. Signs of chronic stress in women with recurrent candida vulvovaginitis. Am J Obstet Gynecol 2005; 193: 1376-81.
Leonard BE. The concept of depression as a dysfunction of the immune system. Curr Immunol Rev 2010; 6: 205-12. 18. Hinkle JL, Cheever KH. Brunner and Suddarth’s textbook of medicalsurgical nursing, Philadelphia: Wolters Kluwer. Pennsylvania; 2018.
Leonard BE. Inflammation and depression. Acta Neuropsychiatr 2018; 30: 1-16.
Ehrström S, Kornfeld D, Rylander E. Perceived stress in women with recurrent vulvovaginal candidiasis. J Psychosom Obstet Gynaecol 2007; 28: 169-76.
Yazdanpanahi Z, Beygi Z, Akbarzadeh M, Zare N. To investigate the relationship between stress, anxiety and depression with sexual function and its domains in women of reproductive age. Int J Med Res Health Sci 2016; 5: 223-31.
Arafa AE, Senosy SA. Female sexual dysfunction in Egyptian women with anxiety: Prevalence and patterns. J Public Health 2018; 26: 545-9.
Jafarnejad F, Kazemayni H, Mazloom R, Emamimoghadam Z, Sefidgaran A. Study on the effect of colporrhaphy on women’s sexual function and satisfaction. Iran J Obstet Gynecol Infertil 2013; 16: 14-23.
Giraldo PC, Polpeta NC, Juliato CR, Yoshida LP, do Amaral RL, Eleutério Junior J. Evaluation of sexual function in brazilian women with recurrent vulvovaginal candidiasis and localized provoked vulvodynia. J Sex Med 2012; 9: 805-11.
Chaudhury S, Mujawar S. Depression and female sexual dysfunction. J Psychiatr Res Treat 2017; 1: 1-2.
Rosen R, Brown C, Heiman J, Leiblum S, Meston C, Shabsigh R, et al. Female Sexual Function Index (FSFI): A multidimensional selfreport instrument for the assessment of female sexual function. J Sex Marital Ther 2000; 26: 191-208.
Mohammadi Kh, Heydari M, Faghihzadeh S. The female sexual function index (FSFI): Validation of the Iranian version. J of Payesh 2008; 7: 269-78.
Antony MM, Bieling PJ, Cox BJ, Enns MW, Swinson RP. Psychometric properties of the 42-item and 21-item versions of the Depression Anxiety Stress Scales in clinical groups and a community sample. Psychological Assessment 1998; 10: 176-81.
Lovibond PF, Lovibond SH. The structure of negative emotional states: Comparison of the Depression Anxiety Stress Scales (DASS) with the Beck Depression and Anxiety Inventories. Behav Res Ther 1995; 33: 335-43.
Samani S, Jokar B. A study on the reliability and validity of the short form of the depression anxiety stress scale (Dass-21). J Social Sci Humanities of Shiraz University 2007; 26: 65-76.
Gungor ANC, Uludag A, Sahin M, Gencer M, Uysal A. Effects of vaginal discharge on female sexual function. Int J Gynecol Obstet 2014; 124: 27-9.
Akimoto-Gunther L, Bonfim-Mendonça Pde S, Takahachi G, Irie MM, Miyamoto S, Consolaro ME, et al. Highlights regarding host predisposing factors to recurrent vulvovaginal candidiasis: Chronic Stress and Reduced Antioxidant Capacity. PloS One 2016; 11: e0158870.
Nyirjesy P, Peyton C, Weitz MV, Mathew L, Culhane JF. Causes of chronic vaginitis: analysis of a prospective database of affected women. Obstet Gynecol 2006; 108: 1185-91.
Meyer H, Goettlicher S, Mendling W. Stress as a cause of chronic recurrent vulvovaginal candidosis and the effectiveness of the conventional antimycotic therapy. Mycoses 2006; 49: 202-9.
Mazinani R, AkbariMehr M, Kaskian A, Kashanian M. Evaluation of prevalence of sexual dysfunctions and its related factors in women. Razi J Med Sci 2012; 19: 61-8.
Bradford A, Meston C M. The impact of anxiety on sexual arousal in women. Behav Res Ther 2006; 44: 1067-77.
Sreelakshmy K, Velayudhan R, Kuriakose D, Nair R. Sexual dysfunction in females with depression: a cross-sectional study. Trends Psychiatry Psychother 2017; 39: 106-9.
Clayton AH, Hamilton DV. Female sexual dysfunction. Psychiatr Clin North Am 2010; 33: 323-38.

APA	Moshfeghy Z, Tahari S, Janghorban R, NAJIB F, Mani A, sayadi m (2020). Association of sexual function and psychological symptoms including depression, anxiety and stress in women with recurrent vulvovaginal candidiasis. , 90 - 96.
Chicago	Moshfeghy Zeinab,Tahari Somayeh,Janghorban Roksana,NAJIB Fatemeh Sadat,Mani Arash,sayadi mehrab Association of sexual function and psychological symptoms including depression, anxiety and stress in women with recurrent vulvovaginal candidiasis. (2020): 90 - 96.
MLA	Moshfeghy Zeinab,Tahari Somayeh,Janghorban Roksana,NAJIB Fatemeh Sadat,Mani Arash,sayadi mehrab Association of sexual function and psychological symptoms including depression, anxiety and stress in women with recurrent vulvovaginal candidiasis. , 2020, ss.90 - 96.
AMA	Moshfeghy Z,Tahari S,Janghorban R,NAJIB F,Mani A,sayadi m Association of sexual function and psychological symptoms including depression, anxiety and stress in women with recurrent vulvovaginal candidiasis. . 2020; 90 - 96.
Vancouver	Moshfeghy Z,Tahari S,Janghorban R,NAJIB F,Mani A,sayadi m Association of sexual function and psychological symptoms including depression, anxiety and stress in women with recurrent vulvovaginal candidiasis. . 2020; 90 - 96.
IEEE	Moshfeghy Z,Tahari S,Janghorban R,NAJIB F,Mani A,sayadi m "Association of sexual function and psychological symptoms including depression, anxiety and stress in women with recurrent vulvovaginal candidiasis." , ss.90 - 96, 2020.
ISNAD	Moshfeghy, Zeinab vd. "Association of sexual function and psychological symptoms including depression, anxiety and stress in women with recurrent vulvovaginal candidiasis". (2020), 90-96.

APA	Moshfeghy Z, Tahari S, Janghorban R, NAJIB F, Mani A, sayadi m (2020). Association of sexual function and psychological symptoms including depression, anxiety and stress in women with recurrent vulvovaginal candidiasis. Journal of the Turkish-German Gynecological Association, 21(2), 90 - 96.
Chicago	Moshfeghy Zeinab,Tahari Somayeh,Janghorban Roksana,NAJIB Fatemeh Sadat,Mani Arash,sayadi mehrab Association of sexual function and psychological symptoms including depression, anxiety and stress in women with recurrent vulvovaginal candidiasis. Journal of the Turkish-German Gynecological Association 21, no.2 (2020): 90 - 96.
MLA	Moshfeghy Zeinab,Tahari Somayeh,Janghorban Roksana,NAJIB Fatemeh Sadat,Mani Arash,sayadi mehrab Association of sexual function and psychological symptoms including depression, anxiety and stress in women with recurrent vulvovaginal candidiasis. Journal of the Turkish-German Gynecological Association, vol.21, no.2, 2020, ss.90 - 96.
AMA	Moshfeghy Z,Tahari S,Janghorban R,NAJIB F,Mani A,sayadi m Association of sexual function and psychological symptoms including depression, anxiety and stress in women with recurrent vulvovaginal candidiasis. Journal of the Turkish-German Gynecological Association. 2020; 21(2): 90 - 96.
Vancouver	Moshfeghy Z,Tahari S,Janghorban R,NAJIB F,Mani A,sayadi m Association of sexual function and psychological symptoms including depression, anxiety and stress in women with recurrent vulvovaginal candidiasis. Journal of the Turkish-German Gynecological Association. 2020; 21(2): 90 - 96.
IEEE	Moshfeghy Z,Tahari S,Janghorban R,NAJIB F,Mani A,sayadi m "Association of sexual function and psychological symptoms including depression, anxiety and stress in women with recurrent vulvovaginal candidiasis." Journal of the Turkish-German Gynecological Association, 21, ss.90 - 96, 2020.
ISNAD	Moshfeghy, Zeinab vd. "Association of sexual function and psychological symptoms including depression, anxiety and stress in women with recurrent vulvovaginal candidiasis". Journal of the Turkish-German Gynecological Association 21/2 (2020), 90-96.