Yıl: 2020 Cilt: 23 Sayı: 3 Sayfa Aralığı: 364 - 374 Metin Dili: Türkçe DOI: 10.5505/kpd.2020.27576 İndeks Tarihi: 19-10-2020

Şizotipi kavramı ve şizotipal kişilik bozukluğu

Öz:
Şizofreni pozitif, negatif belirtiler, bilişsel bozulma, dezorganizsayon ve benzeri boyutlardan oluşan ve buboyutların farklı düzeylerde kesişimi nedeniyle farklıgörünümlerle karşımıza çıkan bir bozukluktur. Şizofrenibenzeri tabloların tanımlanması ilk olarak şizofrenihastalarının ailelerinde psikoz benzeri belirtilerin biryığılım gösterdiği izlenimine dayanmaktadır. Sonrasındayapılan çalışmalarda paranoid, şizoid ve şizotipal kişilikbozuklukları bu spektrumda şizofreniyle karşılaştırılarakincelenmiştir. Özellikle şizotipal kişilik bozukluğunun birkişilik bozukluğu olmaktan çok farklı şizotipi boyutlarınınbir arada ve yoğun olarak görüldüğü, ilerleyici olmayanbir şizofreni spektrum bozukluğu olduğu düşüncesigiderek baskın hale gelmektedir. Kişilik bozukluklarıiçinde şizofreni ile en fazla genetik ortaklığı bulunanşizotipal kişilik bozukluğudur. Şizotipi terimi ilk kezşizofreni benzeri psikoz fenotipi olarak tanımlanmıştır.Günümüze kadar yapılan çalışmalarla şizotipinin, tıpkışizofreni gibi farklı boyutlarının olduğu ve bu boyutlarınklinik olmayan populasyonda ve psikoz riski altındakibireylerde yaygın olarak karşılığının olduğu gösterilmiştir.Aynı zamanda şizofreni ve şizotipinin birbiriyle ilişkiliboyutlarının benzer nörobiyolojik temelleri olduğubulunmuştur. Tanımı gereği şizofreni prodromu ancakşizofreni gelişmiş hastalarda geriye yönelik adı konabilecekbir durumdur. Bu nedenle şizotipal kişilik bozukluğuve yüksek şizotipi şizofreni prodromunu yansıtmaktanziyade yelpazenin içinde yer alan bir yatkınlık göstergesidir.Psikoz etiyopatogenezinin aydınlatılması,şizofreninin erken tanısı, duyarlılaştırıcı etkenlere müdahaleve psikotik kırılmanın önlenmesi açısından sınırdayer alan bu olguların tanımlanması önem taşımaktadır.
Anahtar Kelime:

The concept of schizotypy and schizotypal personality disorder

Öz:
Schizophrenia is a disorder that consists of positive, negative symptoms, cognitive impairment, disorganization and various dimensions and manifested as several clinical appearances because of different intersections of these dimensions at different levels. The description of the schizophrenia-like clinical picture is based primarily on the finding that psychosis-like symptoms have accumulated in families of patients with schizophrenia. The following studies have examined paranoid, schizoid and schizotypal personality disorders in this spectrum by comparing them to schizophrenia. The idea intensely becomes more dominant in the literature that especially schizotypal personality disorder (SPD) is a non-progressive schizophrenia spectrum disorder in which different dimensions of schizotypy are seen together rather than a personality disorder. Among the personality disorders, SPD has the strongest genetic relationship with schizophrenia. The term schizotypy was first described as a schizophrenia-like psychosis phenotype. To date, studies have shown schizotypy has different dimensions, such as schizophrenia, and that reflections of these dimensions are common in non-clinical populations and individuals at risk for psychosis. At the same time, several studies found related dimensions of schizophrenia and schizotypy have similar neurobiological bases. As per the definiton of prodrome is a condition can only be defined retrospectively in patients with schizophrenia. Therefore, schizotypal personality disorder and high schizotypy are predisposition indicators within the spectrum rather than reflecting the schizophrenia prodrome. Identifying of these borderline cases is important for uncovering etiopathogenesis of psychosis, early diagnosis of schizophrenia, intervention to predisposing factors and prevention of psychotic break.
Anahtar Kelime:

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APA MISIR E, Alptekin K (2020). Şizotipi kavramı ve şizotipal kişilik bozukluğu. , 364 - 374. 10.5505/kpd.2020.27576
Chicago MISIR EMRE,Alptekin Koksal Şizotipi kavramı ve şizotipal kişilik bozukluğu. (2020): 364 - 374. 10.5505/kpd.2020.27576
MLA MISIR EMRE,Alptekin Koksal Şizotipi kavramı ve şizotipal kişilik bozukluğu. , 2020, ss.364 - 374. 10.5505/kpd.2020.27576
AMA MISIR E,Alptekin K Şizotipi kavramı ve şizotipal kişilik bozukluğu. . 2020; 364 - 374. 10.5505/kpd.2020.27576
Vancouver MISIR E,Alptekin K Şizotipi kavramı ve şizotipal kişilik bozukluğu. . 2020; 364 - 374. 10.5505/kpd.2020.27576
IEEE MISIR E,Alptekin K "Şizotipi kavramı ve şizotipal kişilik bozukluğu." , ss.364 - 374, 2020. 10.5505/kpd.2020.27576
ISNAD MISIR, EMRE - Alptekin, Koksal. "Şizotipi kavramı ve şizotipal kişilik bozukluğu". (2020), 364-374. https://doi.org/10.5505/kpd.2020.27576
APA MISIR E, Alptekin K (2020). Şizotipi kavramı ve şizotipal kişilik bozukluğu. Klinik Psikiyatri Dergisi, 23(3), 364 - 374. 10.5505/kpd.2020.27576
Chicago MISIR EMRE,Alptekin Koksal Şizotipi kavramı ve şizotipal kişilik bozukluğu. Klinik Psikiyatri Dergisi 23, no.3 (2020): 364 - 374. 10.5505/kpd.2020.27576
MLA MISIR EMRE,Alptekin Koksal Şizotipi kavramı ve şizotipal kişilik bozukluğu. Klinik Psikiyatri Dergisi, vol.23, no.3, 2020, ss.364 - 374. 10.5505/kpd.2020.27576
AMA MISIR E,Alptekin K Şizotipi kavramı ve şizotipal kişilik bozukluğu. Klinik Psikiyatri Dergisi. 2020; 23(3): 364 - 374. 10.5505/kpd.2020.27576
Vancouver MISIR E,Alptekin K Şizotipi kavramı ve şizotipal kişilik bozukluğu. Klinik Psikiyatri Dergisi. 2020; 23(3): 364 - 374. 10.5505/kpd.2020.27576
IEEE MISIR E,Alptekin K "Şizotipi kavramı ve şizotipal kişilik bozukluğu." Klinik Psikiyatri Dergisi, 23, ss.364 - 374, 2020. 10.5505/kpd.2020.27576
ISNAD MISIR, EMRE - Alptekin, Koksal. "Şizotipi kavramı ve şizotipal kişilik bozukluğu". Klinik Psikiyatri Dergisi 23/3 (2020), 364-374. https://doi.org/10.5505/kpd.2020.27576