Efficiency of mechanical thrombectomy in acute ischemic stroke patients

The aim of this single-center study is to assess the outcomes in patients with acute ischemic stroke underwent endovascular mechanical thrombectomy. The data andoutcome of patients who were admitted due to acute ischemic stroke caused by a large vessel occlusion in the anterior or posterior circulation and treated with endovascular stent retriever mechanical thrombectomy between 2014 and 2018 were retrospectively evaluated. Recanalization success was assessed based on Thrombolysis inCerebral Infarction (TICI) scores, and the TICI grades 2b and 3 were considered as ‘successful’. Functional outcomes of the patients were assessed by modified RankinScale (mRS) at the 3rd month follow up and a score of ≤2 points was considered as ‘good clinical outcome’. Successful recanalization was achieved in 34 patients (69%).At the 3rd month follow-up, 23 patients (46,9%) had mRS scores of ≤2 points. The overall mortality rate at the 90th day was %30 (n=15). After endovascular thrombectomy, symptomatic intracranial hemorrhage was seen in 9 patients, groin hematoma due to vascular access in 5 patients, which did not require additional treatment, andpseudoaneurysm in 3 patients. Stent retriever mechanical thrombectomy is an effective and safe procedure in patients admitted due to acute ischemic stroke caused bylarge vessel occlusion.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

1. Rha JH, Saver JL. The impact of recanalization on iskemic stroke outcomes. Stroke. 2007;38:967-73.
2. Emberson J, Lees KR, Lyden P, et al. Effect of treatment delay, age and stroke severity on the effects of intravenous thrombolysis with alteplase for acut ischaemic stroke: a meta-analysis of individual patient data from randomized trials. Lancet. 2014,29;384:1929-35.
3. Bhatia R1, Hill MD, Shobha N, et al. Low rates of acute recanalization with intravenous recombinant tissue plasminogen activator in ischemic stroke: realworld experience and a call for action. Stroke. 2010;41:2254-8.
4. Riedel CH, Zimmermann P, Jensen-Kondering U, et al. The importance of size: successful recanalization by intravenous thrombolysis in acute anteriorstroke depends on thrombus length. Stroke. 2011;42:1775-7.
5. Kharitonova TV, Melo TP, Andersen G, et al. Importance of cerebral artery recanalization in patients with stroke with and without neurological improvement after intravenous thrombolysis. Stroke. 2013;44:2513-8.
6. Behme D, Mpotsaris A, Zeyen P, et al. Emergency stenting of the extracranial internal carotid artery in combination with anterior circulation thrombectomy in acute ischemic stroke: a retrospective multicenter study. AJNR Am J Neuroradiol. 2015;36:2340-5.
7. Berkhemer OA, Fransen PS, Beumer D, et al. A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med. 2015:1;372:11-20.
8. Goyal M, Demchuk AM, Menon BK, et al. Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med. 2015 12; 372:1019-30.
9. Campbell BC, Mitchell PJ, Kleinig TJ, et al. Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med. 2015; 372:1009-18.
10. Saver JL, Goyal M, Bonafe A, et al. Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med. 2015;11;372:2285-95.
11. Jovin TG, Chamorro A, Cobo E, et al. Thrombectomy within 8 hours after symptom onset in ischemic stroke. N Engl J Med. 2015;11;372:2296-306.
12. Broderick JP, Palesch YY, Demchuk AM, et al. Endovascular therapy after intravenous t-PA versus t-PA alone skroke. N Engl J Med. 2013;7;368:893-903
13. Lees KR, Bluhmki E, von Kummer R, et al. Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials. Lancet 2010;375:1695-703.
14. Zhu W, Churilov L, Campbell BC, et al. Large-Vessel Occlusion Is Associated with Poor Outcomes in Stroke Patient Aged 80 Years or Older Who Underwent Intravenous Trombolysis. J Stroke Cerebrovasc Dis. 2014;23:2888-93.
15. Vidale S, Agostoni E. Endovascular Treatment of ischemic stroke: an uptade meta-analyis of efficacy and safety. Vasc Endovascular Surg. 2017;51: 215-9.

APA	Kolu M, Yıldırım I, Kaya A, Kamisli S, kaplan y, durak m, GÜRBÜZ S, SARAÇ K (2020). Efficiency of mechanical thrombectomy in acute ischemic stroke patients. , 700 - 703. 10.5455/medscience.2020.06.105
Chicago	Kolu Mehmet,Yıldırım Ismail Okan,Kaya Ahmet Turan,Kamisli Suat,kaplan yuksel,durak mehmet akif,GÜRBÜZ SÜKRÜ,SARAÇ KAYA Efficiency of mechanical thrombectomy in acute ischemic stroke patients. (2020): 700 - 703. 10.5455/medscience.2020.06.105
MLA	Kolu Mehmet,Yıldırım Ismail Okan,Kaya Ahmet Turan,Kamisli Suat,kaplan yuksel,durak mehmet akif,GÜRBÜZ SÜKRÜ,SARAÇ KAYA Efficiency of mechanical thrombectomy in acute ischemic stroke patients. , 2020, ss.700 - 703. 10.5455/medscience.2020.06.105
AMA	Kolu M,Yıldırım I,Kaya A,Kamisli S,kaplan y,durak m,GÜRBÜZ S,SARAÇ K Efficiency of mechanical thrombectomy in acute ischemic stroke patients. . 2020; 700 - 703. 10.5455/medscience.2020.06.105
Vancouver	Kolu M,Yıldırım I,Kaya A,Kamisli S,kaplan y,durak m,GÜRBÜZ S,SARAÇ K Efficiency of mechanical thrombectomy in acute ischemic stroke patients. . 2020; 700 - 703. 10.5455/medscience.2020.06.105
IEEE	Kolu M,Yıldırım I,Kaya A,Kamisli S,kaplan y,durak m,GÜRBÜZ S,SARAÇ K "Efficiency of mechanical thrombectomy in acute ischemic stroke patients." , ss.700 - 703, 2020. 10.5455/medscience.2020.06.105
ISNAD	Kolu, Mehmet vd. "Efficiency of mechanical thrombectomy in acute ischemic stroke patients". (2020), 700-703. https://doi.org/10.5455/medscience.2020.06.105

APA	Kolu M, Yıldırım I, Kaya A, Kamisli S, kaplan y, durak m, GÜRBÜZ S, SARAÇ K (2020). Efficiency of mechanical thrombectomy in acute ischemic stroke patients. Medicine Science, 9(3), 700 - 703. 10.5455/medscience.2020.06.105
Chicago	Kolu Mehmet,Yıldırım Ismail Okan,Kaya Ahmet Turan,Kamisli Suat,kaplan yuksel,durak mehmet akif,GÜRBÜZ SÜKRÜ,SARAÇ KAYA Efficiency of mechanical thrombectomy in acute ischemic stroke patients. Medicine Science 9, no.3 (2020): 700 - 703. 10.5455/medscience.2020.06.105
MLA	Kolu Mehmet,Yıldırım Ismail Okan,Kaya Ahmet Turan,Kamisli Suat,kaplan yuksel,durak mehmet akif,GÜRBÜZ SÜKRÜ,SARAÇ KAYA Efficiency of mechanical thrombectomy in acute ischemic stroke patients. Medicine Science, vol.9, no.3, 2020, ss.700 - 703. 10.5455/medscience.2020.06.105
AMA	Kolu M,Yıldırım I,Kaya A,Kamisli S,kaplan y,durak m,GÜRBÜZ S,SARAÇ K Efficiency of mechanical thrombectomy in acute ischemic stroke patients. Medicine Science. 2020; 9(3): 700 - 703. 10.5455/medscience.2020.06.105
Vancouver	Kolu M,Yıldırım I,Kaya A,Kamisli S,kaplan y,durak m,GÜRBÜZ S,SARAÇ K Efficiency of mechanical thrombectomy in acute ischemic stroke patients. Medicine Science. 2020; 9(3): 700 - 703. 10.5455/medscience.2020.06.105
IEEE	Kolu M,Yıldırım I,Kaya A,Kamisli S,kaplan y,durak m,GÜRBÜZ S,SARAÇ K "Efficiency of mechanical thrombectomy in acute ischemic stroke patients." Medicine Science, 9, ss.700 - 703, 2020. 10.5455/medscience.2020.06.105
ISNAD	Kolu, Mehmet vd. "Efficiency of mechanical thrombectomy in acute ischemic stroke patients". Medicine Science 9/3 (2020), 700-703. https://doi.org/10.5455/medscience.2020.06.105