Yıl: 2019 Cilt: 15 Sayı: 3 Sayfa Aralığı: 158 - 162 Metin Dili: İngilizce DOI: 10.5152/ejbh.2019.4727 İndeks Tarihi: 24-10-2020

The Effect of Mini-Latissimus Dorsi Flap (MLDF) Reconstruction on Shoulder Function in Breast Cancer Patients

Öz:
Objective: The aim of this study is to investigate the effect of mini latissimus dorsi flap (MLDF) reconstruction on ipsilateral shoulder functions.Materials and Methods: Those included in the study are the patients aged between 23 and 73, who were operated with the diagnosis of early breastcancer (cT1-3)N0). The first group includes the patients who had sentinel lymph node biopsy (SLNB) with partial mastectomy. The second groupconsists of the patients who had axillary lymph nodule dissection (ALND) with partial mastectomy. The third group includes the patients who hadSLNB and MLDF with partial mastectomy. The fourth group includes the patients who had ALND and MLDF with partial mastectomy. Patients’Quick Disabilities of the Arm, Shoulder and Hand (Q-DASH) score work model point were recorded.Results: 174 patients were included in this study. According to Q-DASH score, no functional change was detected in 69.5% of the patients, whereasslight functional loss was identified in 23.6%, moderate functional loss in 5.7%, severe functional loss 1.1%. In the comparison of Q-DASH scoresin surgery groups, while these four groups were being analyzed, a significant difference was determined (p=0.007). When dual analyses were made,it was also established that the difference resulted from the group to which ALND and MLDF were applied together.Conclusion: We conclude that MLDF application for reconstruction purposes after breast surgery has a negative impact on shoulder functions ofthe patients who had both of partial mastectomy and ALND.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. DeSantis CE, Bray F, Ferlay J, Lortet-Tieulent J, Anderson BO, Jemal A. International Variation in Female Breast Cancer Incidence and Mortality Rates. Cancer Epidemiol Biomarkers Prev 2015; 24: 1495-1506. (PMID: 26359465) [CrossRef]
  • 2. Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, Parkin DM, Forman D, Bray F. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer 2015; 136: E359-E386. (PMID: 25220842) [CrossRef]
  • 3. Özmen V. Breast Cancer in Turkey: Clinical and Histopathological Characteristics (Analysis of 13.240 Patients). J Breast Health 2014; 10: 98- 105. (PMID: 28331652) [CrossRef]
  • 4. Cho J, Jung SY, Lee JE, Shim EJ, Kim NH, Kim Z, Sohn G, Youn HJ, Kim KS, Kim H, Lee JW, Lee MH. A review of breast cancer survivorship issues from survivors perspectives. J Breast Cancer 2014; 17: 189-199. (PMID: 25320616) [CrossRef]
  • 5. Ditsch N, Bauerfeind I, Vodermaier A, Tripp C, Löhrs B, Toth B, Himsl I, Graeser M, Harbeck N, Lenhard M. A retrospective investigation of women's experience with breast reconstruction after mastectomy. Arch Gynecol Obstet 2013; 287: 555-561. (PMID: 23090185) [CrossRef]
  • 6. Cubasch H, Dickens C, Joffe M, Duarte R, Murugan N, Tsai Chih M, Moodley K, Sharma V, Ayeni O, Jacobson JS, Neugut AI, McCormack V, Ruff P. Breast cancer survival in Soweto, Johannesburg, South Africa: A receptor-defined cohort of women diagnosed from 2009 to 11. Cancer Epidemiol 2018; 52: 120-127. (PMID: 29306221) [CrossRef]
  • 7. Senkus E, Kyriakides S, Penault-Llorca F, Poortmans P, Thompson A, Zackrisson S, Cardoso F. Primary breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2013; 24: 7-23. (PMID: 23970019) [CrossRef]
  • 8. Thiruchelvam PTR, McNeill F, Jallali N, Harris P, Hogben K. Postmastectomy breast reconstruction. BMJ 2013; 347: 5903. (PMID: 24128977) [CrossRef]
  • 9. Alço G, Igdem S, Okkan S, Dincer M, Sarsenov D, Ilgun AS, Agacayak F, Elbüken F, Ercan T, Selamoglu D, Ozmen V. Replacement of the tumor bed following oncoplastic breast conserving surgery with immediate latissimus dorsi mini flap. Mol Clin Oncol 2016; 5: 365-371. (PMID: 27699027) [CrossRef]
  • 10. Noguchi M, Saito Y, Mizukami Y, Nonomura A, Ohta N, Koyasaki N, Taniya T, Miyazaki I. Breast deformity, its correction and assessment of breast-conserving surgery. Breast Cancer Res Treat 1991; 18: 111-118. (PMID: 1912608) [CrossRef]
  • 11. Nos C, Fitoussi A, Bourgeois D, Fourquet A, Salmon RJ, Klough KB. Conservative treatment of lower pole breast cancers by bilateral mammoplasty and radiotherapy. Eur J Surg Oncol 1998; 24: 508-514. (PMID: 9870725) [CrossRef]
  • 12. Spector DJ, Mayer DK, Knafi K, Pusic A. Women's recovery experiences after breast cancer reconstruction surgery. J Psychosoc Oncol 2011; 29: 664-676. (PMID: 22035539) [CrossRef]
  • 13. Winters ZE, Afzal M, Balta V, Freeman J, Llewellyn-Bennett R, Rayter Z, Cook J, Greenwood R, King MT. Prospective Trial Management Group. Patientreported outcomes and their predictors at 2- and 3-year follow-up after immediate latissimus dorsi breast reconstruction and adjuvant treatment. Br J Surg 2016; 103: 524-536. (PMID: 26924354) [CrossRef]
  • 14. Hamdi M, Decorte T, Demuynck M, Defrene B, Fredrickx A, Van Maele G, De Pypere H, Van Landuyt K, Blondeel P, Vanderstraeten G, Monstrey S. Shoulder function after harvesting a thoracodorsal artery perforator flap. Plast Reconstr Surg 2008; 122: 1111-1117. (PMID: 18827644) [CrossRef]
  • 15. Szychta P, Butterworth M, Dixon M, Kulkami D, Raine C, Stewart K. Breast reconstruction with the denervated latissimus dorsi musculocutaneous flap. Breast 2013; 22: 667-672. (PMID: 23374963) [CrossRef]
  • 16. Tomita K, Yano K, Nishibayashi A, Fukai M, Miyasaka M, Hosokawa K. The role of latissimus dorsi myocutaneous flaps in secondary breast reconstruction after breast-conserving surgery. Eplasty 2013; 13: 206-214. (PMID: 23837111)
  • 17. Bhatt CR, Prajapati B, Patil DS, Patel VD, Singh BGP, Mehta CD. Variation in the insertion of the latissimus dorsi and its clinical importance. J Orthop 2013; 10: 25-28. (PMID: 24403744) [CrossRef]
  • 18. Itani Y, Hagiwara A, Hashimoto T, Isogai N, Kusuhara H. Preliminary Study of PGA Fabric for Seromas at Latissimus Dorsi Flap Donor Sites. Plast Reconstr Surg Glob Open 2017; 5: e1499. (PMID: 29184727) [CrossRef]
  • 19. Button J, Scott J, Taghizadeh R, Weiler-Mithoff E, Hart AM. Shoulder function following autologous LD breast reconstruction. A prospective three year observational study comparing quilting and non-quilting donor site techniques. J Plast Reconstr Aesthet Surg 2010; 63: 1505-1512. (PMID: 19819774) [CrossRef]
  • 20. Düger T, Yakut E, Öksüz Ç, Yörükan S, Bilgütay BS, Ayhan Ç, Leblebicioğlu G, Kayıhan H, Kırdı N, Yakut Y, Güler Ç. Reliability and Validity of the Turkish Version of the Disabilities of the Arm, Shoulder and Hand (DASH)Questionnaire. Fizyoter Rehabil 2006; 17: 99-107.
  • 21. Sajid MS, Betal D, Akhter N, Rapisarda IF, Bonomi R. Prevention of postoperative seroma-related morbidity by quilting of latissimus dorsi flap donor site: A systematic review. Clin Breast Cancer 2011; 11: 357-363. (PMID: 21705282) [CrossRef]
  • 22. Hernanz F, González-Noriega M, Sánchez S, Paz L, Muñoz P, Hermana S. Oncoplastic breast conserving surgery with tailored needle-guided excision. Gland Surg 2017; 6: 698-705. (PMID: 29302488) [CrossRef]
  • 23. Dixon JM, Venizelos B, Chan P. Latissimus dorsi miniflap: a new technique for extending breast conservation. Breast 2002; 11: 58-65. (PMID: 14965647) [CrossRef]
  • 24. Mele S, Wright D, Paramanathan N, Laws S, Peiris L, Rainsbury R. Longterm effect of oncoplastic breast-conserving surgery using latissimus dorsi miniflaps on mammographic surveillance and the detection of local recurrence. J Plast Reconstr Aesthet Surg 2017; 70: 1203-1209. (PMID: 28734752) [CrossRef]
  • 25. Jeevan R, Cromwell DA, Browne JP, Caddy CM, Pereira J, Sheppard C, Greenaway K, van der Meulen JH. Findings of a national comparative audit of mastectomy and breast reconstruction survey in England. J Plast Reconstr Aesthet Surg 2014; 67: 1333-1344. (PMID: 24908545) [CrossRef]
  • 26. Smith S. Functional Morbidity Following Latissimus Dorsi Flap Breast Reconstruction. J Adv Pract Oncol 2014; 5: 181-187. (PMID: 25089217) [CrossRef]
  • 27. Kim Z, Kang SG, Lee MH, Roh JH, Park JH, Lee J, Kim S, Lim CW, Lee MH. Skin-sparing mastectomy and immediate latissimus dorsi flap reconstruction: A retrospective analysis of the surgical and patientreported outcomes. World J Surg Oncol 2012; 10: 259. (PMID: 23192102) [CrossRef]
  • 28. Spear SL, Hess CL. A review of the biomechanical and functional changes in shoulder following transfer of the latissimus dorsi muscles. Plast Reconstr Surg 2005; 115: 2070-2073. (PMID: 15923857) [CrossRef]
  • 29. Glassey N, Perks GB, McCulley SJ. A prospective assessment of shoulder morbidity and recovery time scales following latissimus dorsi breast reconstruction. Plast Reconstr Surg 2008; 122: 1334-1340. (PMID: 18971716) [CrossRef]
  • 30. Koh CE, Morrison WA. Functional impairment after latissimus dorsi flap. ANZ J Surg 2009; 79: 42-47. (PMID: 19183378) [CrossRef]
  • 31. Forthomme B, Heymans O, Jacquemin D, Klinkenberg S, Hoffmann S, Grandjean FX, Crielaard JM, Croisier JL. Shoulder function after latissimus dorsi transfer in breast reconstruction. Clin Physiol Funct Imaging 2010; 30: 406-412. (PMID: 20633032) [CrossRef]
  • 32. Gosselink R, Rouffaer L, Vanhelden P, Piot W, Troosters T, Christiaens M. Recovery of upper limb function after axillary dissection. J Surg Oncol 2003; 83: 204-211. (PMID: 12884231) [CrossRef]
  • 33. Mansel RE, Fallowfield L, Kissin M, Goyal A, Newcombe RG, Dixon JM, Yiangou C, Horgan K, Bundred N, Monypenny I, England D, Sibbering M, Abdullah TI, Barr L, Chetty U, Sinnett DH, Fleissig A, Clarke D, Ell PJ. Randomized multicenter trial of sentinel node biopsy versus standard axillary treatment in operable breast cancer: the ALMANAC Trial. J Natl Cancer Inst 2006; 98: 599-609. (PMID: 16670385) [CrossRef]
APA Duymaz T, erdoğan z, ilgun a, Ordu C, Ucuncu M, ALCO G, Öztürk A, ELBÜKEN F, aktepe f, Ozmen V (2019). The Effect of Mini-Latissimus Dorsi Flap (MLDF) Reconstruction on Shoulder Function in Breast Cancer Patients. , 158 - 162. 10.5152/ejbh.2019.4727
Chicago Duymaz Tomris,erdoğan zeynep,ilgun ahmet serkan,Ordu Cetin,Ucuncu Muhammed,ALCO GUL,Öztürk Alper,ELBÜKEN Filiz,aktepe fatma,Ozmen Vahit The Effect of Mini-Latissimus Dorsi Flap (MLDF) Reconstruction on Shoulder Function in Breast Cancer Patients. (2019): 158 - 162. 10.5152/ejbh.2019.4727
MLA Duymaz Tomris,erdoğan zeynep,ilgun ahmet serkan,Ordu Cetin,Ucuncu Muhammed,ALCO GUL,Öztürk Alper,ELBÜKEN Filiz,aktepe fatma,Ozmen Vahit The Effect of Mini-Latissimus Dorsi Flap (MLDF) Reconstruction on Shoulder Function in Breast Cancer Patients. , 2019, ss.158 - 162. 10.5152/ejbh.2019.4727
AMA Duymaz T,erdoğan z,ilgun a,Ordu C,Ucuncu M,ALCO G,Öztürk A,ELBÜKEN F,aktepe f,Ozmen V The Effect of Mini-Latissimus Dorsi Flap (MLDF) Reconstruction on Shoulder Function in Breast Cancer Patients. . 2019; 158 - 162. 10.5152/ejbh.2019.4727
Vancouver Duymaz T,erdoğan z,ilgun a,Ordu C,Ucuncu M,ALCO G,Öztürk A,ELBÜKEN F,aktepe f,Ozmen V The Effect of Mini-Latissimus Dorsi Flap (MLDF) Reconstruction on Shoulder Function in Breast Cancer Patients. . 2019; 158 - 162. 10.5152/ejbh.2019.4727
IEEE Duymaz T,erdoğan z,ilgun a,Ordu C,Ucuncu M,ALCO G,Öztürk A,ELBÜKEN F,aktepe f,Ozmen V "The Effect of Mini-Latissimus Dorsi Flap (MLDF) Reconstruction on Shoulder Function in Breast Cancer Patients." , ss.158 - 162, 2019. 10.5152/ejbh.2019.4727
ISNAD Duymaz, Tomris vd. "The Effect of Mini-Latissimus Dorsi Flap (MLDF) Reconstruction on Shoulder Function in Breast Cancer Patients". (2019), 158-162. https://doi.org/10.5152/ejbh.2019.4727
APA Duymaz T, erdoğan z, ilgun a, Ordu C, Ucuncu M, ALCO G, Öztürk A, ELBÜKEN F, aktepe f, Ozmen V (2019). The Effect of Mini-Latissimus Dorsi Flap (MLDF) Reconstruction on Shoulder Function in Breast Cancer Patients. European Journal of Breast Health, 15(3), 158 - 162. 10.5152/ejbh.2019.4727
Chicago Duymaz Tomris,erdoğan zeynep,ilgun ahmet serkan,Ordu Cetin,Ucuncu Muhammed,ALCO GUL,Öztürk Alper,ELBÜKEN Filiz,aktepe fatma,Ozmen Vahit The Effect of Mini-Latissimus Dorsi Flap (MLDF) Reconstruction on Shoulder Function in Breast Cancer Patients. European Journal of Breast Health 15, no.3 (2019): 158 - 162. 10.5152/ejbh.2019.4727
MLA Duymaz Tomris,erdoğan zeynep,ilgun ahmet serkan,Ordu Cetin,Ucuncu Muhammed,ALCO GUL,Öztürk Alper,ELBÜKEN Filiz,aktepe fatma,Ozmen Vahit The Effect of Mini-Latissimus Dorsi Flap (MLDF) Reconstruction on Shoulder Function in Breast Cancer Patients. European Journal of Breast Health, vol.15, no.3, 2019, ss.158 - 162. 10.5152/ejbh.2019.4727
AMA Duymaz T,erdoğan z,ilgun a,Ordu C,Ucuncu M,ALCO G,Öztürk A,ELBÜKEN F,aktepe f,Ozmen V The Effect of Mini-Latissimus Dorsi Flap (MLDF) Reconstruction on Shoulder Function in Breast Cancer Patients. European Journal of Breast Health. 2019; 15(3): 158 - 162. 10.5152/ejbh.2019.4727
Vancouver Duymaz T,erdoğan z,ilgun a,Ordu C,Ucuncu M,ALCO G,Öztürk A,ELBÜKEN F,aktepe f,Ozmen V The Effect of Mini-Latissimus Dorsi Flap (MLDF) Reconstruction on Shoulder Function in Breast Cancer Patients. European Journal of Breast Health. 2019; 15(3): 158 - 162. 10.5152/ejbh.2019.4727
IEEE Duymaz T,erdoğan z,ilgun a,Ordu C,Ucuncu M,ALCO G,Öztürk A,ELBÜKEN F,aktepe f,Ozmen V "The Effect of Mini-Latissimus Dorsi Flap (MLDF) Reconstruction on Shoulder Function in Breast Cancer Patients." European Journal of Breast Health, 15, ss.158 - 162, 2019. 10.5152/ejbh.2019.4727
ISNAD Duymaz, Tomris vd. "The Effect of Mini-Latissimus Dorsi Flap (MLDF) Reconstruction on Shoulder Function in Breast Cancer Patients". European Journal of Breast Health 15/3 (2019), 158-162. https://doi.org/10.5152/ejbh.2019.4727