Can immature reticulocyte fraction be an inflammatory biomarker in late-preterm infants diagnosed with congenital pneumonia?

baydemir, canan; Çetin, Ceren; ER, İlkay

doi:10.5455/annalsmedres.2020.02.161

Can immature reticulocyte fraction be an inflammatory biomarker in late-preterm infants diagnosed with congenital pneumonia?

İlkay ER, (Sağlık Bilimleri Üniversitesi, Kocaeli Derince Eğitim Araştırma Hastanesi, Neonatoloji Bölümü, Kocaeli, Türkiye)

Ceren ÇETİN, (Sağlık Bilimleri Üniversitesi, Kocaeli Derince Eğitim Araştırma Hastanesi, Pediatrik Enfeksiyon Hastalıkları Bölümü, Kocaeli, Türkiye)

Canan BAYDEMİR (Kocaeli Üniversitesi, Tıp Fakültesi, Biyoistatistik ve Tıp Bilişimi Anabilim Dalı, Kocaeli, Türkiye)

Annals of Medical Research

1 0

Yıl: 2020 Cilt: 27 Sayı: 7 Sayfa Aralığı: 1918 - 1923 Metin Dili: İngilizce DOI: 10.5455/annalsmedres.2020.02.161 İndeks Tarihi: 30-10-2020

Can immature reticulocyte fraction be an inflammatory biomarker in late-preterm infants diagnosed with congenital pneumonia?

Öz:

Aim: Congenital pneumonia (CP) is serious respiratory infection of the neonates. Recently introduced hematological parameter,immature reticulocyte fraction (IRF), has been investigated to gather clinical information about the prognosis of anemia as well asto measure the level of inflammatory activity in adult patients. In this study of late-preterm infants diagnosed with CP, we comparedIRF with common sepsis biomarkers and evaluated its role as inflammatory biomarker in neonates.Material and Methods: Late-preterms were categorized based on infectious vs. non-infectious etiology of the respiratory distress.Blood samples were taken at 48-72 hours after birth. IRF was measured with Sysmex XN-3000. Biomarkers such as complete bloodcount parameters, C-reactive protein (CRP), and procalcitonin (PCT) were used for the comparison.Results: Total of 25 late-preterms, 14 in CP-group and 11 in transient tachypnea of the newborn (TTN) group were included study.The groups were comparable in terms of gestational age, birth weight and cesarean section rate. The proportion of prolongedmembrane rupture was signifiantly higher in CP-group. No signifiant differences were found between hemoglobin, hematocritand reticulocyte in both groups (p>0.05). The value of IRF was higher in CP-group compared to in TTN-group, although it was notstatistically signifiant (37.8±7.2% vs. 31.6±9.4%, respectively) (p=0.08). PCT was signifiantly higher in CP-group (p=0.017). Nodifferences were found in other biomarkers between the groups (p>0.05).Conclusion: Our results suggest that PCT can be diagnostic marker in CP, but further studies are needed to confim role of IRF inneonatal inflammation.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	ER İ, Çetin C, baydemir c (2020). Can immature reticulocyte fraction be an inflammatory biomarker in late-preterm infants diagnosed with congenital pneumonia?. , 1918 - 1923. 10.5455/annalsmedres.2020.02.161
Chicago	ER İlkay,Çetin Ceren,baydemir canan Can immature reticulocyte fraction be an inflammatory biomarker in late-preterm infants diagnosed with congenital pneumonia?. (2020): 1918 - 1923. 10.5455/annalsmedres.2020.02.161
MLA	ER İlkay,Çetin Ceren,baydemir canan Can immature reticulocyte fraction be an inflammatory biomarker in late-preterm infants diagnosed with congenital pneumonia?. , 2020, ss.1918 - 1923. 10.5455/annalsmedres.2020.02.161
AMA	ER İ,Çetin C,baydemir c Can immature reticulocyte fraction be an inflammatory biomarker in late-preterm infants diagnosed with congenital pneumonia?. . 2020; 1918 - 1923. 10.5455/annalsmedres.2020.02.161
Vancouver	ER İ,Çetin C,baydemir c Can immature reticulocyte fraction be an inflammatory biomarker in late-preterm infants diagnosed with congenital pneumonia?. . 2020; 1918 - 1923. 10.5455/annalsmedres.2020.02.161
IEEE	ER İ,Çetin C,baydemir c "Can immature reticulocyte fraction be an inflammatory biomarker in late-preterm infants diagnosed with congenital pneumonia?." , ss.1918 - 1923, 2020. 10.5455/annalsmedres.2020.02.161
ISNAD	ER, İlkay vd. "Can immature reticulocyte fraction be an inflammatory biomarker in late-preterm infants diagnosed with congenital pneumonia?". (2020), 1918-1923. https://doi.org/10.5455/annalsmedres.2020.02.161

APA	ER İ, Çetin C, baydemir c (2020). Can immature reticulocyte fraction be an inflammatory biomarker in late-preterm infants diagnosed with congenital pneumonia?. Annals of Medical Research, 27(7), 1918 - 1923. 10.5455/annalsmedres.2020.02.161
Chicago	ER İlkay,Çetin Ceren,baydemir canan Can immature reticulocyte fraction be an inflammatory biomarker in late-preterm infants diagnosed with congenital pneumonia?. Annals of Medical Research 27, no.7 (2020): 1918 - 1923. 10.5455/annalsmedres.2020.02.161
MLA	ER İlkay,Çetin Ceren,baydemir canan Can immature reticulocyte fraction be an inflammatory biomarker in late-preterm infants diagnosed with congenital pneumonia?. Annals of Medical Research, vol.27, no.7, 2020, ss.1918 - 1923. 10.5455/annalsmedres.2020.02.161
AMA	ER İ,Çetin C,baydemir c Can immature reticulocyte fraction be an inflammatory biomarker in late-preterm infants diagnosed with congenital pneumonia?. Annals of Medical Research. 2020; 27(7): 1918 - 1923. 10.5455/annalsmedres.2020.02.161
Vancouver	ER İ,Çetin C,baydemir c Can immature reticulocyte fraction be an inflammatory biomarker in late-preterm infants diagnosed with congenital pneumonia?. Annals of Medical Research. 2020; 27(7): 1918 - 1923. 10.5455/annalsmedres.2020.02.161
IEEE	ER İ,Çetin C,baydemir c "Can immature reticulocyte fraction be an inflammatory biomarker in late-preterm infants diagnosed with congenital pneumonia?." Annals of Medical Research, 27, ss.1918 - 1923, 2020. 10.5455/annalsmedres.2020.02.161
ISNAD	ER, İlkay vd. "Can immature reticulocyte fraction be an inflammatory biomarker in late-preterm infants diagnosed with congenital pneumonia?". Annals of Medical Research 27/7 (2020), 1918-1923. https://doi.org/10.5455/annalsmedres.2020.02.161