TY  - JOUR
TI  - The role of positron emission tomography/computed tomography in the evaluation of anterior mediastinal masses and differentiating between the histological subtypes of thymic epithelial neoplasms
AB  - Background: This study aims to investigate the role of positron emissiontomography/computed tomography in differentiating between benignand malignant anterior mediastinal masses and between the histologicalsubtypes of thymic epithelial neoplasms.Methods: This retrospective study included a total of 57 patients(30 males, 27 females; mean age 48.9 years; range, 14 to 78 years)who underwent an fluorodeoxyglucose positron emission tomography/computed tomography with an indication of an anterior mediastinalmass between May 2010 and November 2018. The maximum andmean standardized uptake values, metabolic tumor volume, total lesionglycolysis, and mean Hounsfield units of the lesions were determined.Thymic epithelial neoplasms were classified as low-risk thymomas(A, AB, B1), high-risk thymomas (B2, B3), and thymic carcinomas.All lesions were evaluated together and divided into two groups asbenign and malignant, and positron emission tomography/computedtomography parameters of the two groups were compared.Results: Histopathological examination identified 29 thymic epithelialneoplasms (13 low-risk, 14 high-risk, two thymic carcinomas), 13 benignlesions, and 15 malignant lesions. No significant correlation was identifiedbetween the positron emission tomography/computed tomographyparameters and histological subtype of thymic epithelial neoplasms. Therewas no significant difference in the maximum and mean standardizeduptake values, metabolic tumor volume, total lesion glycolysis, and meanHounsfield units of the lesions between low-risk and high-risk thymiccarcinomas. The maximum and mean standardized uptake values,metabolic tumor volume, and mean Hounsfield units of the lesions weresignificantly higher in the malignant group than in the benign group.Conclusion: Our study results show that positron emission tomography/computed tomography is useful in the differentiation of benign andmalignant anterior mediastinal masses, although it fails to differentiatebetween the histological subtypes of thymic epithelial neoplasms.
AU  - BUDAK, EMİNE
AU  - YANARATEŞ, AHMET
DO  - 10.5606/tgkdc.dergisi.2020.18432
PY  - 2020
JO  - Türk Göğüs Kalp Damar Cerrahisi Dergisi
VL  - 28
IS  - 2
SN  - 1301-5680
SP  - 315
EP  - 321
DB  - TRDizin
UR  - http://search/yayin/detay/371502
ER  -