Pharmacognostical Studies on Acer campestre L. subsp. campestre

Burcu SEN UTSUKARCİ, (İstanbul Üniversitesi, Eczacılık Fakültesi, Farmakognozi Anabilim Dalı, İstanbul, Türkiye)
Yavuz Selim BAL, (İstanbul Üniversitesi, Eczacılık Fakültesi, İstanbul, Türkiye)
Bahar GÜRDAL, (İstanbul Üniversitesi Eczacılık Fakültesi, Farmasötik Botanik Anabilim Dalı, İstanbul, Türkiye)
Hilal BARDAKÇI, (Acıbadem Mehmet Ali Aydınlar Üniversitesi, Eczacılık Fakültesi, Farmakognozi Anabilim Dalı, İstanbul, Türkiye)
Fatıma Nur YILMAZ, (İstanbul Üniversitesi, Eczacılık Fakültesi, Farmasötik Mikrobiyoloji Anabilim Dalı, İstanbul, Türkiye)
Sibel DÖŞLER (İstanbul Üniversitesi, Eczacılık Fakültesi, Farmasötik Mikrobiyoloji Anabilim Dalı, İstanbul, Türkiye)
International Journal of Secondary Metabolite
8 1
Yıl: 2020 Cilt: 7 Sayı: 2 Sayfa Aralığı: 126 - 138 Metin Dili: İngilizce DOI: 10.21448/ijsm.711952 İndeks Tarihi: 02-11-2020

Pharmacognostical Studies on Acer campestre L. subsp. campestre

Öz:
This study on Acer campestre L. subsp. campestre, used traditionallyin treatments of various inflammation disorders, especially hemorrhoids andrheumatism, aimed to determine the total phenolic contents, the antioxidant andantimicrobial potentials, and the chemical composition profile of the extracts andsubextracts from maple syrup and Acer campestre L. subsp. campestre leaves andtwigs. The antioxidant activities of maple syrup extracts and subextracts wereexamined by 2,2-diphenyl-1-picryl-hydrazyl (DPPH), and the total phenoliccontents of all samples were determined using the Folin-Ciocalteu reagent (FCR)method. Also, they were tested for their antimicrobial activities by microbrothdilution technique. Catechic tannin, saponins and flavonoids are determined in itsleaves and twigs by preliminary qualitative phytochemical analysis. Thealcoholic extracts obtained by 48-hour maceration (91.2%), ethyl acetatesubextract of alcohol extracts obtained by 24-hour maceration (91.1%) andalcohol extracts obtained by 24-hour maceration (88.8%) exhibited higher radicalscavenging activity than other samples, while the decoction and infusion hadmoderate activities. Beside of this, it was found that the syrup and its subextractshave more total phenolic contents than other extracts. The alcohol extractsobtained by 24-hour maceration and by 48-hour maceration exhibited higheractivity against Candida albicans (78 μg/mL and 156 μg/mL, respectively). Onlythe alcohol extract obtained by 48-hour maceration and ethyl acetate subextractof syrup showed an activity against Escherichia coli, while all samples exceptbutanol subextract of syrup have an antibacterial activity against Pseudomonasaeruginosa.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • [1]. Ravipati, A.S., Zhang, L., Koyyalamudi, S.R., Jeong, S.C., Reddy, N., Bartlett, J., Satyanarayanan, M. (2012). Antioxidant and anti-inflammatory activities of selected Chinese medicinal plants and their relation with antioxidant content. BMC Complement. Altern. Med., 12, Article number: 173. https://doi.org/10.1186/1472-6882-12-173
  • [2]. Schinella, G.R., Tournier, H.A., Prieto, J.M. (2002). Antioxidant activity of antiinflammatory plant extracts. Life Sciences, 70, 1023-1033. https://doi.org/10.1016/S0024- 3205(01)01482-5
  • [3]. Zhang, L., Ravipati, A.S., Koyyalamudi, S.R., Jeong, S.C., Reddy, N., Smith, P.T., Bartlett, J., Shanmugam, K., Münch, D.G., Wu, M.J. (2011). Antioxidant and Anti-inflammatory Activities of Selected Medicinal Plants Containing Phenolic and Flavonoid compounds. J. Agric. Food Chem., 59, 12361–12367. https://doi.org/10.1021/jf203146e
  • [4]. Talhouk, R., Karam, C., Fostok, S., El-Jouni, W., Barbour, E. (2007). Anti-inflammatory bioactivities in plant extracts. J. Med. Food, 10, 1 10. https://doi.org/10.1089/jmf.2005.0 55
  • [5]. Zhang, Y., Yuan, T., Li, L., Nahar, P., Slitt, A., Seeram, N.P. (2014). Chemical compositional, biological, and safety studies of a novel maple syrup derived extract for nutraceutical applications. J. Agric. Food Chem., 62, 6687 6698. https://doi.org/10.1021 /jf501924y
  • [6]. Perkins, T.D., van den Berg, A.K. (2009). Maple syrup-production, composition, chemistry, and sensory characteristics. In Advances in Food and Nutrition Research; Taylor, S.L. Ed.; Academic Press, Elsevier, USA, 2009, Volume 56, pp. 101−143. ISBN: 978-0-12-374439-5
  • [7]. Storz, G., Darvill, A.G., Albersheim, P. (1986). Characterization of polysaccharides isolated from maple syrup. Phytochemistry, 25, 437-441, https://doi.org/10.1016/S0031- 9422(00)85497-7
  • [8]. Ball, D. W. (2007). The chemical composition of maple syrup. J. Chem. Educ., 84, 1647- 1650. https://doi.org/10.1021/ed084p1647
  • [9]. Li, L., Seeram, N.P. (2010). Maple syrup phytochemicals include lignans, coumarins, a stilbene and other previously unreported antioxidant phenolic compounds. J. Agric. Food Chem., 58, 11673-11679. https://doi.org/10.1021/jf1033398
  • [10]. Li, L., Seeram, N.P. (2011). Further investigation into maple syrup yields three new lignans, a new phenylpropanoid, and twenty-six other phytochemicals. J. Agric. Food Chem., 59, 7708-7716. https://doi.org/10.1021/jf2011613
  • [11]. Li, L., Seeram, N.P. (2011). Quebecol, a novel phenolic compound isolated from Canadian maple syrup. J. Funct. Foods, 3, 125-128. https://doi.org/10.1016/j.jff.2011.02.004
  • [12]. Yuan, T., Li, L., Zhang, Y., Seeram, N.P. (2013). Pasteurized and sterilized maple sap as functional beverages: Chemical composition and antioxidant activities. J. Funct. Foods, 5, 1582−1590. https://doi.org/10.1016/j.jff.2013.06.009
  • [13]. Kermasha, S., Goetghebeur, M., Dumont, J. (1995). Determination of phenolic compound profiles in maple products by high performance liquid chromatography. J. Agric. Food Chem., 43, 708−716. https://doi.org/10.1021/jf00051a028
  • [14]. Abou-Zaid, M.M., Nozzolillo, C., Tonon, A., Coppens, M., Lombardo, A.D.A. (2008). High performance liquid chromatography characterization and identification of antioxidant polyphenols in maple syrup. Pharm. Biol., 46, 117−125. https://doi.org/10.1080/13880200701735031
  • [15]. González-Sarrías, A., Li, L., Seeram, N. P. (2012). Effects of maple (Acer) plant part extracts on proliferation, apoptosis and cell cycle arrest of human tumorigenic and nontumorigenic colon cells. Phytother. Res., 26, 995−1002. https://doi.org/10.1002/ptr.3677
  • [16]. Legault, J., Girard-Lalancette, K., Grenon, C., Dussault, C., Pichette, A. (2010). Antioxidant activity, inhibition of nitric oxide overproduction, and in vitro antiproliferative effect of maple sap and syrup from Acer saccharum. J. Med. Food, 13, 460−468. https://doi.org/10.1089/jmf.2009.0029
  • [17]. Nahar, P.P., Driscoll, M. V., Li, L., Slitt, A. L., Seeram, N.P. (2014). Phenolic mediated anti-inflammatory properties of a maple syrup extract in RAW 264.7 murine macrophages. J. Funct. Foods, 6, 126−136. https://doi.org/10.1016/j.jff.2013.09.026
  • [18]. Watanabe, Y., Kamei, A., Shinozaki, F., Ishijima, T., Iida, K., Nakai, Y., Arai, S., Abe, K. (2011). Ingested maple syrup evokes a possible liverprotecting effect-physiologic and genomic investigations with rats. Biosci. Biotechnol. Biochem., 75, 2408−2410. https://d oi.org/10.1271/bbb.110532
  • [19]. Nagai, N., Ito, Y., Taga, A. (2013). Comparison of the enhancement of plasma glucose levels in type 2 diabetes Otsuka Long-Evans Tokushima fatty rats by oral administration of sucrose or maple syrup. J. Oleo Sci., 62, 737−743. https://doi.org/10.5650/jos.62.737
  • [20]. Thériault, M., Caillet, S., Kermasha, S., Lacroix, M. (2006). Antioxidant, antiradical and antimutagenic activities of phenolic compounds present in maple products. Food Chem., 98, 490–501. https://doi.org/10.1016/j.foodchem.2005.05.079
  • [21]. González-Sarrías, A., Yuan, T., Seeram, N.P. (2012). Cytotoxicity and structure activity relationship studies of maplexins A-I, gallotannins from red maple (Acer rubrum). Food Chem. Toxicol., 50, 1369–1376. https://doi.org/10.1016/j.fct.2012.02.031
  • [22]. Honma, A., Koyama, T., Yazawa, K. (2010). Anti-hyperglycemic effects of sugar maple Acer saccharum and its constituent acertannin. Food Chem., 123, 390– 394. https://doi.org/10.1016/j.foodchem.2010.04.052
  • [23]. Wu, D., Wu, X.D., You, X.-F., Ma, X.-F., Tian, W.-X.. (2010). Inhibitory Effects on Bacterial Growth and beta-Ketoacyl-ACP Reductase by Different Species of Maple Leaf Extracts and Tannic Acid. Phytother. Res., 24, S35-S41. https://doi.org/10.1002/ptr.2873
  • [24]. Jedinak, A., Valachova, M., Maliar, T., Sturdik, E. (2010). Antiprotease activity of selected Slovak medicinal plants. Pharmazie, 65, 137-140. https://doi.org/10.1691/ph.20 10.9668
  • [25]. Ecevit Genc G., Ozhatay N. (2006). An ethnobotanical study in Catalca (European part of Istanbul) II. Turk. J. Pharm. Sci., 3, 73-89.
  • [26]. Tuzlacı, E. (2016). Turkiye Bitkileri Geleneksel Ilac Rehberi; Istanbul Medikal Saglik ve Yayincilik, Istanbul, Turkey, pp. 630-631. ISBN: 9786054949717
  • [27]. Baytop, B. (1980). Farmakognozi, Volume I, 3. Edition; Istanbul Universitesi Yayinlari, Baha Matbaası, Istanbul, Turkey, pp. 206-207.
  • [28]. Bardakci, H., Celep, E., Kurt-Celep, I., Deniz, I., Sen-Utsukarci, B., Akaydin, G. (2019). A comparative investigation on phenolic composition, antioxidant and antimicrobial potentials of Salvia heldreichiana Boiss. ex Bentham extracts. S. Afr. J. Bot., 125, 72-80. https://doi.org/10.1016/j.sajb.2019.07.010
  • [29]. Singleton, V.L., Rossi Jr., J.A. (1965). Colorimetry of total phenolics with phosphomolibdic-phosphotungtic acid reagents. Am. J. Enol. and Vitic., 16, 144-158.
  • [30]. Clinical and Laboratory Standards Institute (CLSI), (2000). Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts; Approved Standard M27-A NCCLS, Wayne, Pennsylvania.
  • [31]. Clinical and Laboratory Standards Institute (CLSI), (2012). Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically: Approved Standard, Ninth edition, M7-A9. Wayne, Pennsylvania.
  • [32]. de Freitas Araújo, M.G., Hilário, F., Vilegas, W., Dos Santos, L.C., Brunetti, I.L., Sotomayor, C.E., Bauab, T.M. (2012). Correlation among antioxidant, antimicrobial, hemolytic, and antiproliferative properties of Leiothrix spiralis leaves extract. Int. J. Mol. Sci., 13, 9260-9277. https://doi.org/10.3390/ijms13079260
  • [33]. Park, S.J., Shin E.H., Kim, D.H., Rha, Y.-A. (2016). Nutrition components and physicochemical properties of Acer termentosum Maxim. leaf. Culi. Sci. & Hos. Res., 22, 27-38. https://doi.org/10.20878/cshr.2016.22.8.003
  • [34]. Watanabe, M., Devkota, H.P. (2017). Antioxidant phenolic constituents from the leaves of Acer ginnala var. aidzuense. Journal of Natural Remedies, 17, 9-12. https://doi.org/10.18311/jnr/2017/15632
  • [35]. Choi, Y.-H., Han S.S., Lee, H.O, Baek, S.H. (2005). Biological activity of bioactive components from Acer ginnala Max. Bull. Korean Chem. Soc., 26, 1450-1452. https://doi.org/10.5012/bkcs.2005.26.9.1450
  • [36]. Meda, N.R., Suwal, S., Rott, M., Poubelle, P.E., Stevanovic, T. (2016). Investigation of extracts from red and sugar maple buds as potential sources of antioxidant phytochemicals. Current Topics in Phytochemistry, 13, 69-78.
  • [37]. Atroune, F., Chaker, S., Djebbar, R., Dahmani-Megrerouche, M. (2019). Comparative evaluation of phenolics content and antioxidant activity of leaves and branches of field maple (Acer campestre) from two populations of Northeastern Algeria. Analele Universităţii din Oradea, Fascicula Biologie, 26, 7-13.
  • [38]. Geoffroy, T.R., Fortin, Y., Stevanovic, T. (2017). Hot-water extraction optimization of sugar maple (Acer saccharum Marsh.) and red maple (Acer rubrum L.) bark applying principal component analysis. J. Wood Chem. Technol., 37, 261-272. https://doi.org/10.1080/02773813.2017.1279631
  • [39]. Park, K.H., Yoon, K.H., Yin, J., Le, T.T., Ahn, H.S., Yoon, S.H., Lee, M.W. (2017). Antioxidative and anti-inflammatory activities of galloyl derivatives and antidiabetic activities of Acer ginnala. Evid.-Based Complementary Altern. Med., Article ID 6945912, 8 pages. https://doi.org/10.1155/2017/6945912
  • [40]. Lee, C.S., Jang, E.-R., Kim, Y.J., Seo, S.J., Choi, S.E., Lee, M.W. (2011). Polyphenol acertannin prevents TRAIL-induced apoptosis in human keratinocytes by suppressing apoptosis-related protein activation. Chem.-Biol. Interact., 189, 52–59. https://doi.org/10.1016/j.cbi.2010.10.009
  • [41]. Moskalenko, S.A. (1986). Preliminary screening of far-eastern ethnomedicinal plants for antibacterial activity. J. Ethnopharmacol., 15,231-259. https://doi.org/10.1016/0378- 8741(86)90163-7
  • [42]. Zhang, F., Luo, S.Y., Ye, Y.B., Zhao, W.H., Sun, X.G., Wang, Z.Q., Li, R., Sun, Y.H., Tian, W.X., Zhang, Y.X. (2008). The antibacterial efficacy of an aceraceous plant [shantung maple (Acer truncatum Bunge)] may be related to inhibition of bacterial betaoxoacyl- acyl carrier protein reductase (FabG). Biotechnol. Appl. Biochem., 51, 73-78. https://doi.org/10.1042/BA20070255
  • [43]. Khan, S., Bakht, J., Shafi M. (2018). Antinociceptive, antimicrobial potential and phytochemical screening of different solvent extracted samples from the stem of Acer pentapomicum. Pak. J. Pharm. Sci., 31, 1457-1461.
APA Sen-Utsukarci B, Bal Y, Gurdal B, BARDAKÇI H, Yılmaz F, Dosler s (2020). Pharmacognostical Studies on Acer campestre L. subsp. campestre. , 126 - 138. 10.21448/ijsm.711952
Chicago Sen-Utsukarci Burcu,Bal Yavuz Selim,Gurdal Bahar,BARDAKÇI Hilal,Yılmaz Fatıma nur,Dosler sibel Pharmacognostical Studies on Acer campestre L. subsp. campestre. (2020): 126 - 138. 10.21448/ijsm.711952
MLA Sen-Utsukarci Burcu,Bal Yavuz Selim,Gurdal Bahar,BARDAKÇI Hilal,Yılmaz Fatıma nur,Dosler sibel Pharmacognostical Studies on Acer campestre L. subsp. campestre. , 2020, ss.126 - 138. 10.21448/ijsm.711952
AMA Sen-Utsukarci B,Bal Y,Gurdal B,BARDAKÇI H,Yılmaz F,Dosler s Pharmacognostical Studies on Acer campestre L. subsp. campestre. . 2020; 126 - 138. 10.21448/ijsm.711952
Vancouver Sen-Utsukarci B,Bal Y,Gurdal B,BARDAKÇI H,Yılmaz F,Dosler s Pharmacognostical Studies on Acer campestre L. subsp. campestre. . 2020; 126 - 138. 10.21448/ijsm.711952
IEEE Sen-Utsukarci B,Bal Y,Gurdal B,BARDAKÇI H,Yılmaz F,Dosler s "Pharmacognostical Studies on Acer campestre L. subsp. campestre." , ss.126 - 138, 2020. 10.21448/ijsm.711952
ISNAD Sen-Utsukarci, Burcu vd. "Pharmacognostical Studies on Acer campestre L. subsp. campestre". (2020), 126-138. https://doi.org/10.21448/ijsm.711952
APA Sen-Utsukarci B, Bal Y, Gurdal B, BARDAKÇI H, Yılmaz F, Dosler s (2020). Pharmacognostical Studies on Acer campestre L. subsp. campestre. International Journal of Secondary Metabolite, 7(2), 126 - 138. 10.21448/ijsm.711952
Chicago Sen-Utsukarci Burcu,Bal Yavuz Selim,Gurdal Bahar,BARDAKÇI Hilal,Yılmaz Fatıma nur,Dosler sibel Pharmacognostical Studies on Acer campestre L. subsp. campestre. International Journal of Secondary Metabolite 7, no.2 (2020): 126 - 138. 10.21448/ijsm.711952
MLA Sen-Utsukarci Burcu,Bal Yavuz Selim,Gurdal Bahar,BARDAKÇI Hilal,Yılmaz Fatıma nur,Dosler sibel Pharmacognostical Studies on Acer campestre L. subsp. campestre. International Journal of Secondary Metabolite, vol.7, no.2, 2020, ss.126 - 138. 10.21448/ijsm.711952
AMA Sen-Utsukarci B,Bal Y,Gurdal B,BARDAKÇI H,Yılmaz F,Dosler s Pharmacognostical Studies on Acer campestre L. subsp. campestre. International Journal of Secondary Metabolite. 2020; 7(2): 126 - 138. 10.21448/ijsm.711952
Vancouver Sen-Utsukarci B,Bal Y,Gurdal B,BARDAKÇI H,Yılmaz F,Dosler s Pharmacognostical Studies on Acer campestre L. subsp. campestre. International Journal of Secondary Metabolite. 2020; 7(2): 126 - 138. 10.21448/ijsm.711952
IEEE Sen-Utsukarci B,Bal Y,Gurdal B,BARDAKÇI H,Yılmaz F,Dosler s "Pharmacognostical Studies on Acer campestre L. subsp. campestre." International Journal of Secondary Metabolite, 7, ss.126 - 138, 2020. 10.21448/ijsm.711952
ISNAD Sen-Utsukarci, Burcu vd. "Pharmacognostical Studies on Acer campestre L. subsp. campestre". International Journal of Secondary Metabolite 7/2 (2020), 126-138. https://doi.org/10.21448/ijsm.711952
Sayfa Oluşturulma Tarihi
26-04-2024 6:29

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