Should there be a specific length of the colon-rectum segment to be resected for an adequate number of lymph nodes in cases of colorectal cancers? A retrospective multi-center study

Öz:

Objective: This study aimed to evaluate the question as to whether there should be a certain length of the colon-rectum segment to be resected forcorrect lymph node staging in cases with colorectal cancer.Material and Methods: The files and electronic datas of the patients had been undergone surgery for colorectal cancer between January 2011 andJune 2016 were evaluated. The patients were divided into two groups; Group I= ≥ 12 lymph nodes, and Group II= lymph nodes less than 12 (< 12) lymphnodes.Results: Mean age of the 327 participants in this study was 64.30 ± 12.20. Mean length of resected colon-rectum segment was 25.61 (± 14.07) cm; meannumber of dissected lymph nodes was 20.63 ± 12.30. Median length of the resected colon was 24 cm (range: 145-6) in Group I and 20 cm (range: 52-9) inGroup II; a significant difference was found between the groups (p= 0.002). Factors associated with adequate lymph node dissection included type of theoperation (p= 0.001), tumor location (p= 0.005), tumor T stage (p= 0.001), condition of metastasis in the lymph node (p= 0.008) and stage of the disease (p=0.031). Overall survival was 62.4 ± 1.31 months, and Group I and Group II survival was 61.4 ± 1.39 months and 66.7 ± 3.25 months, respectively (p= 0.449).Conclusion: Results of the study showed that ≥ 12 lymph nodes would likely be dissected when the length of the resected colon-rectum segment is >21 cm. We conclude that the removed colonic size can be significant when performed with oncological surgical standardization.

Anahtar Kelime:

Kolorektal kanserlerde yeterli lenf nodu sayısı için çıkarılacak kolon-rektum segmentinin belirli bir uzunluğu olmalı mı? Retrospektif çok merkezli bir çalışma

Öz:

Giriş ve Amaç: Bu çalışma, kolorektal kanserli olgularda doğru lenf nodu evrelemesi için rezeke edilecek kolon-rektum segmentinin belirli bir uzunluğunun olup olmadığı sorusunu değerlendirmeyi amaçlamaktadır. Gereç ve Yöntem: Kolorektal kanserli hastaların Ocak 2011-Haziran 2016 tarihleri arasında ameliyat geçiren dosyaları ve elektronik verileri değerlendirildi. Hastalar iki gruba ayrıldı; Grup I= ≥ 12 lenf nodu ve Grup II= 12’den az lenf nodu sayısı. Bulgular: Çalışmaya yaş ortalaması 64,30 ± 12,20 olan 327 olgu dahil edilmiştir. Rezeke edilen kolon-rektum segmentinin ortalama toplam uzunluğu 25,61 (± 14,07) cm; diseke edilen ortalama lenf nodu sayısı 20,63 ± 12,30 idi. Çıkarılan ortalama kolon-rektum uzunluğu Grup I’de 24 cm (145-6) ve Grup II’de 20 cm (52-9) olup gruplar arasında anlamlı fark bulunmuştur (p= 0,002). Yeterli lenf nodu diseksiyonu ile ilişkili faktörler; operasyonun türü (p= 0,001), tümör yeri (p= 0,005), tümör T evresi (p= 0,001), lenf nodunda metastaz durumu (p= 0,008) ve hastalığın evresi (p= 0,031) olarak bulunmuştur. Ortalama sağkalım 62,4 ± 1,31 ay idi. Grup I ve Grup II’de sırasıyla, 61,4 ± 1,39 ay ve 66,7 ± 3,25 idi (p= 0,449). Sonuç: Bu çalışma, çıkarılan kolon-rektum uzunluğu > 21 cm olduğunda ≥ 12 lenf nodu çıkarılabileceğini gösterdi. Çıkarılan bu kolon-rektum uzunluğunun onkolojik cerrahi standardizasyonuyla beraber yapıldığında anlamlı olacağını düşünüyoruz.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Ureyen O, ULUSOY C, Acar A, Sağlam F, Kızıloğlu İ, alemdar a, Atahan M, Dadalı E, KARAISLI S, AYDIN M, İlhan E, GÜVEN H (2020). Should there be a specific length of the colon-rectum segment to be resected for an adequate number of lymph nodes in cases of colorectal cancers? A retrospective multi-center study. , 23 - 32. 10.5578/turkjsurg.4550
Chicago	Ureyen Orhan,ULUSOY CEMAL,Acar Atahan,Sağlam Fazıl,Kızıloğlu İlker,alemdar ali,Atahan Murat Kemal,Dadalı Emrah,KARAISLI Serkan,AYDIN MEHMET CAN,İlhan Enver,GÜVEN HAKAN Should there be a specific length of the colon-rectum segment to be resected for an adequate number of lymph nodes in cases of colorectal cancers? A retrospective multi-center study. (2020): 23 - 32. 10.5578/turkjsurg.4550
MLA	Ureyen Orhan,ULUSOY CEMAL,Acar Atahan,Sağlam Fazıl,Kızıloğlu İlker,alemdar ali,Atahan Murat Kemal,Dadalı Emrah,KARAISLI Serkan,AYDIN MEHMET CAN,İlhan Enver,GÜVEN HAKAN Should there be a specific length of the colon-rectum segment to be resected for an adequate number of lymph nodes in cases of colorectal cancers? A retrospective multi-center study. , 2020, ss.23 - 32. 10.5578/turkjsurg.4550
AMA	Ureyen O,ULUSOY C,Acar A,Sağlam F,Kızıloğlu İ,alemdar a,Atahan M,Dadalı E,KARAISLI S,AYDIN M,İlhan E,GÜVEN H Should there be a specific length of the colon-rectum segment to be resected for an adequate number of lymph nodes in cases of colorectal cancers? A retrospective multi-center study. . 2020; 23 - 32. 10.5578/turkjsurg.4550
Vancouver	Ureyen O,ULUSOY C,Acar A,Sağlam F,Kızıloğlu İ,alemdar a,Atahan M,Dadalı E,KARAISLI S,AYDIN M,İlhan E,GÜVEN H Should there be a specific length of the colon-rectum segment to be resected for an adequate number of lymph nodes in cases of colorectal cancers? A retrospective multi-center study. . 2020; 23 - 32. 10.5578/turkjsurg.4550
IEEE	Ureyen O,ULUSOY C,Acar A,Sağlam F,Kızıloğlu İ,alemdar a,Atahan M,Dadalı E,KARAISLI S,AYDIN M,İlhan E,GÜVEN H "Should there be a specific length of the colon-rectum segment to be resected for an adequate number of lymph nodes in cases of colorectal cancers? A retrospective multi-center study." , ss.23 - 32, 2020. 10.5578/turkjsurg.4550
ISNAD	Ureyen, Orhan vd. "Should there be a specific length of the colon-rectum segment to be resected for an adequate number of lymph nodes in cases of colorectal cancers? A retrospective multi-center study". (2020), 23-32. https://doi.org/10.5578/turkjsurg.4550

APA	Ureyen O, ULUSOY C, Acar A, Sağlam F, Kızıloğlu İ, alemdar a, Atahan M, Dadalı E, KARAISLI S, AYDIN M, İlhan E, GÜVEN H (2020). Should there be a specific length of the colon-rectum segment to be resected for an adequate number of lymph nodes in cases of colorectal cancers? A retrospective multi-center study. Turkish Journal of Surgery, 36(1), 23 - 32. 10.5578/turkjsurg.4550
Chicago	Ureyen Orhan,ULUSOY CEMAL,Acar Atahan,Sağlam Fazıl,Kızıloğlu İlker,alemdar ali,Atahan Murat Kemal,Dadalı Emrah,KARAISLI Serkan,AYDIN MEHMET CAN,İlhan Enver,GÜVEN HAKAN Should there be a specific length of the colon-rectum segment to be resected for an adequate number of lymph nodes in cases of colorectal cancers? A retrospective multi-center study. Turkish Journal of Surgery 36, no.1 (2020): 23 - 32. 10.5578/turkjsurg.4550
MLA	Ureyen Orhan,ULUSOY CEMAL,Acar Atahan,Sağlam Fazıl,Kızıloğlu İlker,alemdar ali,Atahan Murat Kemal,Dadalı Emrah,KARAISLI Serkan,AYDIN MEHMET CAN,İlhan Enver,GÜVEN HAKAN Should there be a specific length of the colon-rectum segment to be resected for an adequate number of lymph nodes in cases of colorectal cancers? A retrospective multi-center study. Turkish Journal of Surgery, vol.36, no.1, 2020, ss.23 - 32. 10.5578/turkjsurg.4550
AMA	Ureyen O,ULUSOY C,Acar A,Sağlam F,Kızıloğlu İ,alemdar a,Atahan M,Dadalı E,KARAISLI S,AYDIN M,İlhan E,GÜVEN H Should there be a specific length of the colon-rectum segment to be resected for an adequate number of lymph nodes in cases of colorectal cancers? A retrospective multi-center study. Turkish Journal of Surgery. 2020; 36(1): 23 - 32. 10.5578/turkjsurg.4550
Vancouver	Ureyen O,ULUSOY C,Acar A,Sağlam F,Kızıloğlu İ,alemdar a,Atahan M,Dadalı E,KARAISLI S,AYDIN M,İlhan E,GÜVEN H Should there be a specific length of the colon-rectum segment to be resected for an adequate number of lymph nodes in cases of colorectal cancers? A retrospective multi-center study. Turkish Journal of Surgery. 2020; 36(1): 23 - 32. 10.5578/turkjsurg.4550
IEEE	Ureyen O,ULUSOY C,Acar A,Sağlam F,Kızıloğlu İ,alemdar a,Atahan M,Dadalı E,KARAISLI S,AYDIN M,İlhan E,GÜVEN H "Should there be a specific length of the colon-rectum segment to be resected for an adequate number of lymph nodes in cases of colorectal cancers? A retrospective multi-center study." Turkish Journal of Surgery, 36, ss.23 - 32, 2020. 10.5578/turkjsurg.4550
ISNAD	Ureyen, Orhan vd. "Should there be a specific length of the colon-rectum segment to be resected for an adequate number of lymph nodes in cases of colorectal cancers? A retrospective multi-center study". Turkish Journal of Surgery 36/1 (2020), 23-32. https://doi.org/10.5578/turkjsurg.4550