TY  - JOUR
TI  - High C-reactive protein level as a predictor for appendiceal perforation
AB  - BACKGROUND: Between 18% and 34% of acute appendicitis (AA) patients may have complicated appendicitis. Perforation is themost important complication of AA. Perforation increases morbidity and mortality. In this study, we aimed to investigate the role ofbasic inflammatory markers in the diagnosis of perforated AA.METHODS: A retrospective chart review was conducted of patients who underwent appendectomy with a diagnosis of AA betweenJanuary 2014 and October 2019 at Akdeniz University Faculty of Medicine; and between December 2017 and October 2019 at IstinyeUniversity Faculty of Medicine Hospital. Markers recorded were as follows: white blood cell count, neutrophils, lymphocytes, platelets,c-reactive protein, mean platelet volume, red cell distribution width and eosinophils. Hematological indices were combined to generatethe following three ratios: white cell neutrophil ratio, platelet lymphocyte ratio and neutrophil-lymphocyte ratio.RESULTS: A total of 536 patients with a diagnosis of AA underwent an operation. There were 344 (64.1%) male patients and 192(35.9%) female patients. The mean age of the patients was 36.7±16.2 (15-88) years. There were 94 (17.5%) patients with perforatedAA and 442 (82.5%) patients with non-perforated AA. C-reactive protein (AUC: 0.81, p<0.001) was the most accurate markers indistinguishing the perforated and non-perforated group.CONCLUSION: Elevated CRP level is a nonspecific inflammatory marker in most of the inflammatory diseases. A high CRP levelcan, therefore, be used as a supplement in the diagnosis of perforated AA.
AU  - VURAL, Veli
AU  - ÖZOZAN, Ömer Vefik
DO  - 10.14744/tjtes.2019.14799
PY  - 2020
JO  - Ulusal Travma ve Acil Cerrahi Dergisi
VL  - 26
IS  - 1
SN  - 1306-696X
SP  - 63
EP  - 66
DB  - TRDizin
UR  - http://search/yayin/detay/374995
ER  -