Comparing The Effects of Sugammadex and Neostigmine On Neuromuscular Block and Bispectral Index In Recovery From Intracranial Mass Resection Operations
Yıl: 2020 Cilt: 25 Sayı: 3 Sayfa Aralığı: 371 - 377 Metin Dili: İngilizce DOI: 10.5505/ejm.2020.99705 İndeks Tarihi: 17-11-2020
Comparing The Effects of Sugammadex and Neostigmine On Neuromuscular Block and Bispectral Index In Recovery From Intracranial Mass Resection Operations
Öz: Neuromuscular recovery (NMR) is a critical part of recovery from general anesthesia. Neostigmine is a choline esteraseinhibitor and one of the leading agents which are used for NMR from non-depolarizing neuromuscular block. Its effectdepends on competitive antagonism of the neuromuscular blocking agent (NMBA) in the neuromuscular junction (NMJ).Sugammadex is a new agent which has attracted attention with dramatically rapid NMR from non -depolarizingneuromuscular blocking agents (NDNMBAs). It effects via chemically antagonizing NMBAs.In this study, effects of neostigmine and sugammadex concerning recovery from general anesthesia for intracranial massexcision operations were compared. Totally 60 patients were included in the study. Neostigmine was used for 30 patients,and sugammadex was used for 30 patients. Evaluation criteria were the train of four (TOF), bispectral index (BIS),Glasgow Coma Scale (GCS), Modified Aldrete Score (MAS), Ramsey Sedation Score (RSS), vital signs and existedcomplications.It is observed that NMR and recovery from anesthesia were significantly shorter in the sugammadex group (p<0,05). It isalso seen that the duration of attaining BIS level to 80 was significantly shorter in the sugammadex group but this result isattributed to the artifact of the rapidly increasing neuromuscular activity in the sugammadex group.Conclusion: We suggest that both neostigmine and sugammadex are useful agents for NMR. Sugammadex has mor eadvantages than neostigmine because of rapid onset of action without increased complications but much more studies areneeded about sugammadex to take the place of neostigmine.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | kurcaloglu m, sarihasan b, Çetinoğlu E (2020). Comparing The Effects of Sugammadex and Neostigmine On Neuromuscular Block and Bispectral Index In Recovery From Intracranial Mass Resection Operations. , 371 - 377. 10.5505/ejm.2020.99705 |
| Chicago | kurcaloglu mustafa,sarihasan bahriye binnur,Çetinoğlu Erhan Çetin Comparing The Effects of Sugammadex and Neostigmine On Neuromuscular Block and Bispectral Index In Recovery From Intracranial Mass Resection Operations. (2020): 371 - 377. 10.5505/ejm.2020.99705 |
| MLA | kurcaloglu mustafa,sarihasan bahriye binnur,Çetinoğlu Erhan Çetin Comparing The Effects of Sugammadex and Neostigmine On Neuromuscular Block and Bispectral Index In Recovery From Intracranial Mass Resection Operations. , 2020, ss.371 - 377. 10.5505/ejm.2020.99705 |
| AMA | kurcaloglu m,sarihasan b,Çetinoğlu E Comparing The Effects of Sugammadex and Neostigmine On Neuromuscular Block and Bispectral Index In Recovery From Intracranial Mass Resection Operations. . 2020; 371 - 377. 10.5505/ejm.2020.99705 |
| Vancouver | kurcaloglu m,sarihasan b,Çetinoğlu E Comparing The Effects of Sugammadex and Neostigmine On Neuromuscular Block and Bispectral Index In Recovery From Intracranial Mass Resection Operations. . 2020; 371 - 377. 10.5505/ejm.2020.99705 |
| IEEE | kurcaloglu m,sarihasan b,Çetinoğlu E "Comparing The Effects of Sugammadex and Neostigmine On Neuromuscular Block and Bispectral Index In Recovery From Intracranial Mass Resection Operations." , ss.371 - 377, 2020. 10.5505/ejm.2020.99705 |
| ISNAD | kurcaloglu, mustafa vd. "Comparing The Effects of Sugammadex and Neostigmine On Neuromuscular Block and Bispectral Index In Recovery From Intracranial Mass Resection Operations". (2020), 371-377. https://doi.org/10.5505/ejm.2020.99705 |
| APA | kurcaloglu m, sarihasan b, Çetinoğlu E (2020). Comparing The Effects of Sugammadex and Neostigmine On Neuromuscular Block and Bispectral Index In Recovery From Intracranial Mass Resection Operations. Eastern Journal of Medicine, 25(3), 371 - 377. 10.5505/ejm.2020.99705 |
| Chicago | kurcaloglu mustafa,sarihasan bahriye binnur,Çetinoğlu Erhan Çetin Comparing The Effects of Sugammadex and Neostigmine On Neuromuscular Block and Bispectral Index In Recovery From Intracranial Mass Resection Operations. Eastern Journal of Medicine 25, no.3 (2020): 371 - 377. 10.5505/ejm.2020.99705 |
| MLA | kurcaloglu mustafa,sarihasan bahriye binnur,Çetinoğlu Erhan Çetin Comparing The Effects of Sugammadex and Neostigmine On Neuromuscular Block and Bispectral Index In Recovery From Intracranial Mass Resection Operations. Eastern Journal of Medicine, vol.25, no.3, 2020, ss.371 - 377. 10.5505/ejm.2020.99705 |
| AMA | kurcaloglu m,sarihasan b,Çetinoğlu E Comparing The Effects of Sugammadex and Neostigmine On Neuromuscular Block and Bispectral Index In Recovery From Intracranial Mass Resection Operations. Eastern Journal of Medicine. 2020; 25(3): 371 - 377. 10.5505/ejm.2020.99705 |
| Vancouver | kurcaloglu m,sarihasan b,Çetinoğlu E Comparing The Effects of Sugammadex and Neostigmine On Neuromuscular Block and Bispectral Index In Recovery From Intracranial Mass Resection Operations. Eastern Journal of Medicine. 2020; 25(3): 371 - 377. 10.5505/ejm.2020.99705 |
| IEEE | kurcaloglu m,sarihasan b,Çetinoğlu E "Comparing The Effects of Sugammadex and Neostigmine On Neuromuscular Block and Bispectral Index In Recovery From Intracranial Mass Resection Operations." Eastern Journal of Medicine, 25, ss.371 - 377, 2020. 10.5505/ejm.2020.99705 |
| ISNAD | kurcaloglu, mustafa vd. "Comparing The Effects of Sugammadex and Neostigmine On Neuromuscular Block and Bispectral Index In Recovery From Intracranial Mass Resection Operations". Eastern Journal of Medicine 25/3 (2020), 371-377. https://doi.org/10.5505/ejm.2020.99705 |
