Phytochemical Characterization and Biological Activities of Nepeta cadmea Boiss.

Ozturk, Gozde; Demirci, Betül; Yılmaz, Gülderen; ÇİÇEK, MEHMET

doi:10.21448/ijsm.675128

Phytochemical Characterization and Biological Activities of Nepeta cadmea Boiss.

Gülderen YIILMAZ, (Ankara Üniversitesi, Eczacılık Fakültesi, Farmasötik Botanik Anabilim Dalı, Ankara, Türkiye)

Gözde ÖZTÜRK, (Anadolu Üniversitesi,Eczacılık Fakültesi,Farmakognozi Anabilim Dalı, Eskişehir, Türkiye)

Betül DEMİRCİ, (Anadolu Üniversitesi,Eczacılık Fakültesi,Farmakognozi Anabilim Dalı, Eskişehir, Türkiye)

Mehmet ÇİÇEK (Pamukkale Üniversitesi,Fen ve Sanat Fakültesi,Moleküler Biyoloji ve Genetik Bölümü, Denizli,Türkiye)

International Journal of Secondary Metabolite

5 2

Yıl: 2020 Cilt: 7 Sayı: 1 Sayfa Aralığı: 28 - 34 Metin Dili: İngilizce DOI: 10.21448/ijsm.675128 İndeks Tarihi: 19-11-2020

Phytochemical Characterization and Biological Activities of Nepeta cadmea Boiss.

Öz:

The genus Nepeta(Lamiaceae) is represented by 39 species, in total 50 taxa, 19 of which are endemic, in Turkey. Nepetaspecies are known as “kedinanesi” in Turkish and has many traditional usages such as antispasmodic, diuretic, antiseptic, antitussive,andantiasthmatic activities. The aerial parts of N. cadmeawere hydrodistillated for 3 hours by using Clevengerapparatustogatheressentialoil.Todetermineitschemical characterization, the essential oil was analyzed by GC-FID and GC-MS, simultaneously. 4aα,7α,7aβ-Nepetalactone (74.0%), 4aα,7α,7aα-nepetalactone (4.5%) and caryophyllene oxide (2.5%) were found as major components for essential oil. The potential in vitroantibacterial activity of the essential oil was evaluated using the broth microdilution assay. A panel of human pathogenic strains Escherichia coliNRRL B-3008, Pseudomonas aeruginosaATCC 27853, Salmonella typhimuriumATCC 13311, Bacillus cereusNRRL B-3711 and Streptococcus sanguinisATCC 10556 were used. Minimal Inhibitory Concentrations (MIC) of the samples were determined, where in ciprofloxacin was used as a positive control in the assay. MIC valueswere found 2500, 1000, 600, 600, 600 μg/mL against E. coli, P. aeruginosa, S. typhimurium, B. cereusand S. sanguinis, respectively. Compared the literature, it was seen that the essential oil had lower effective against these strains.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Yılmaz G, Ozturk G, Demirci B, ÇİÇEK M (2020). Phytochemical Characterization and Biological Activities of Nepeta cadmea Boiss.. , 28 - 34. 10.21448/ijsm.675128
Chicago	Yılmaz Gülderen,Ozturk Gozde,Demirci Betül,ÇİÇEK MEHMET Phytochemical Characterization and Biological Activities of Nepeta cadmea Boiss.. (2020): 28 - 34. 10.21448/ijsm.675128
MLA	Yılmaz Gülderen,Ozturk Gozde,Demirci Betül,ÇİÇEK MEHMET Phytochemical Characterization and Biological Activities of Nepeta cadmea Boiss.. , 2020, ss.28 - 34. 10.21448/ijsm.675128
AMA	Yılmaz G,Ozturk G,Demirci B,ÇİÇEK M Phytochemical Characterization and Biological Activities of Nepeta cadmea Boiss.. . 2020; 28 - 34. 10.21448/ijsm.675128
Vancouver	Yılmaz G,Ozturk G,Demirci B,ÇİÇEK M Phytochemical Characterization and Biological Activities of Nepeta cadmea Boiss.. . 2020; 28 - 34. 10.21448/ijsm.675128
IEEE	Yılmaz G,Ozturk G,Demirci B,ÇİÇEK M "Phytochemical Characterization and Biological Activities of Nepeta cadmea Boiss.." , ss.28 - 34, 2020. 10.21448/ijsm.675128
ISNAD	Yılmaz, Gülderen vd. "Phytochemical Characterization and Biological Activities of Nepeta cadmea Boiss.". (2020), 28-34. https://doi.org/10.21448/ijsm.675128

APA	Yılmaz G, Ozturk G, Demirci B, ÇİÇEK M (2020). Phytochemical Characterization and Biological Activities of Nepeta cadmea Boiss.. International Journal of Secondary Metabolite, 7(1), 28 - 34. 10.21448/ijsm.675128
Chicago	Yılmaz Gülderen,Ozturk Gozde,Demirci Betül,ÇİÇEK MEHMET Phytochemical Characterization and Biological Activities of Nepeta cadmea Boiss.. International Journal of Secondary Metabolite 7, no.1 (2020): 28 - 34. 10.21448/ijsm.675128
MLA	Yılmaz Gülderen,Ozturk Gozde,Demirci Betül,ÇİÇEK MEHMET Phytochemical Characterization and Biological Activities of Nepeta cadmea Boiss.. International Journal of Secondary Metabolite, vol.7, no.1, 2020, ss.28 - 34. 10.21448/ijsm.675128
AMA	Yılmaz G,Ozturk G,Demirci B,ÇİÇEK M Phytochemical Characterization and Biological Activities of Nepeta cadmea Boiss.. International Journal of Secondary Metabolite. 2020; 7(1): 28 - 34. 10.21448/ijsm.675128
Vancouver	Yılmaz G,Ozturk G,Demirci B,ÇİÇEK M Phytochemical Characterization and Biological Activities of Nepeta cadmea Boiss.. International Journal of Secondary Metabolite. 2020; 7(1): 28 - 34. 10.21448/ijsm.675128
IEEE	Yılmaz G,Ozturk G,Demirci B,ÇİÇEK M "Phytochemical Characterization and Biological Activities of Nepeta cadmea Boiss.." International Journal of Secondary Metabolite, 7, ss.28 - 34, 2020. 10.21448/ijsm.675128
ISNAD	Yılmaz, Gülderen vd. "Phytochemical Characterization and Biological Activities of Nepeta cadmea Boiss.". International Journal of Secondary Metabolite 7/1 (2020), 28-34. https://doi.org/10.21448/ijsm.675128