TY  - JOUR
TI  - EVALUATION OF THIOL DISULPHIDE HOMEOSTASIS AND NEUTROPHILE LYMPHOCYTE RATIO IN CARBON MONOXIDE INTOXICATION
AB  - Objectives: The aim of this study is to search if using thiol/disulphide homeostasis together with Neutrophile Lymphocyte Ratio (NLR) which are oxidative stress markers in patients who apply to the emergency service with carbon monoxide intoxication is useful regarding diagnosis or not. Materials and Methods: The study was performed prospectively with 45 patients who applied to the emergency service between 01.01.2014 - 01.03.2015 and who were included in the study and 40 healthy persons who were determined as control group. Thiol/disulphide homeostasis parameters (Thiol, disulphide, disulphide / native thiol, disulphide / total thiol, native thiol / total thiol) and NLR which are oxidative stress markers were studied in the patient and control groups by a method which was developed newly by Erel and Neşelioğlu. Results: In persons with carbon monoxide intoxication, a significant difference was detected in NT, TT, index 3 and NLR rates according to the control group. NT, TT and index 3 were found lower in the patient group, and NLR mean values were found higher in the patient group (p =0.005, < 0.001, = 0.032, < 0.001 respectively). Conclusion: To use NLR together with thiol/disulphide homeostasis parameters in the diagnosis of carbon monoxide intoxication is useful regarding diagnosing in these patients.
AU  - ercan haydar, fadime güllü
AU  - Yıldırım, Çağdaş
AU  - Tanrıverdi, Fatih
AU  - Ozhasenekler, Ayhan
AU  - Yuzbasioglu, Yucel
AU  - Gökhan, Servan
AU  - eren, funda
AU  - Kahraman, Fatih Ahmet
DO  - 10.5505/amj.2020.71542
PY  - 2020
JO  - Ankara Medical Journal
VL  - 20
IS  - 1
SN  - 1303-2283
SP  - 47
EP  - 56
DB  - TRDizin
UR  - http://search/yayin/detay/381239
ER  -