Potato (Solanum tuberosum L.) is one of the most important starch crops grown extensively. In this study, theeffects of saline water and proline content on yield and some characteristics of potato were determined. Prolineconcentrations of 0 mM (control), 10 mM, and 20 mM were applied to potato crop irrigated with water withelectrical conductivities of 0.2 dSm-1(control), 3.5 dSm-1, 7 dSm-110 dSm-1and 13 dSm-1. Different levels ofsaline irrigation water were obtained by adding NaCl into the tap water with an EC of 0.2 dSm-1. In the salinewater treatments, a leaching fraction about 20% was applied. The study was conducted between January-June2010 in the pots located in a greenhouse under the Eastern Mediterranean (Hatay, Turkey) conditions. Comparedto the control treatment, the amount of irrigation water and crop water use decreased by 4.5%-18.9% and 3.0%-16.0% depending on soil salinity, respectively. Soil salinity caused a decrease in total tuber yield, mean tuberweight, total dry weight, harvest index, and number of potatoes classified as Grade A, whereas it caused anincrease in total dry matter content. No distinct effects of proline on tuber yield were observed in the treatments ofhigher salt stress. The effect of increasing proline concentration was mostly pronounced in the vegetative and gasexchange parameters.