Prognostic significance of poorly differentiated cluster grading system in intestinal type gastric adenocarcinoma

Semra GÜRÜNLÜOĞLU, (Malatya Turgut Özal Üniversitesi, Eğitim ve Araştırma Hastanesi, Tıbbi Patoloji Anabilim Dalı, Malatya, Türkiye)
Emine TÜRKMEN ŞAMDANCI, (İnönü Üniversitesi, Tıp Fakültesi, Tıbbi Patoloji Anabilim Dalı, Malatya, Türkiye)
Ahmet Kadir ARSLAN, (İnönü Üniversitesi, Tıp Fakültesi, Biyoistatistik ve Tıp Bilişimi Anabilim Dalı, Malatya, Türkiye)
Nusret AKPOLAT, (İnönü Üniversitesi, Tıp Fakültesi, Tıbbi Patoloji Anabilim Dalı, Malatya, Türkiye)
Nurhan ŞAHİN, (Bezmialem Üniversitesi, Tıp Fakültesi, Tıbbi Patoloji Anabilim Dalı, İstanbul, Türkiye)
Hasan GÖKÇE (İnönü Üniversitesi, Tıp Fakültesi, Tıbbi Patoloji Anabilim Dalı, Malatya, Türkiye)
Annals of Medical Research
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Yıl: 2020 Cilt: 27 Sayı: 8 Sayfa Aralığı: 2022 - 2030 Metin Dili: İngilizce DOI: 10.5455/annalsmedres.2020.06.578 İndeks Tarihi: 06-12-2020

Prognostic significance of poorly differentiated cluster grading system in intestinal type gastric adenocarcinoma

Öz:
Aim: Gastric carcinoma is the fourth most common carcinoma worldwide. The relationships established between the tumormorphology and the prognosis have not been very effective until recent times. Poorly Differentiated Clusters (PDCs); are structuresthose can be easily identified in H&E sections. A new grading system based on PDC count has been studied in colorectal carcinoma;and found to be associated with prognosis. We have aimed to investigate this concept in gastric carcinoma.Material and Methods: Our study included 80 cases, consisting of 16 females and 64 males having gastric carcinoma with intestinalmorphology. For each case; conventional grade, PDC grade and prognostic parameters to be applied in the study were determined,and statistically compared.Results: Significant discrepancy was found between the two grading systems. PDC tumor grades were statistically related to; medianmetastatic lymph node counts, metastatic lymph node ratios, lymph node stages (pN) and the presence of perineural invasion.Conclusion: In stomach carcinoma; PDC grading system was found to be related to a significant part of the expected parametersand may have a prognostic value.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA GÜRÜNLÜOĞLU S, Samdanci E, ARSLAN A, AKPOLAT N, Sahin N, GOKÇE H (2020). Prognostic significance of poorly differentiated cluster grading system in intestinal type gastric adenocarcinoma. , 2022 - 2030. 10.5455/annalsmedres.2020.06.578
Chicago GÜRÜNLÜOĞLU SEMRA,Samdanci Emine,ARSLAN Ahmet Kadir,AKPOLAT NUSRET,Sahin Nurhan,GOKÇE HASAN Prognostic significance of poorly differentiated cluster grading system in intestinal type gastric adenocarcinoma. (2020): 2022 - 2030. 10.5455/annalsmedres.2020.06.578
MLA GÜRÜNLÜOĞLU SEMRA,Samdanci Emine,ARSLAN Ahmet Kadir,AKPOLAT NUSRET,Sahin Nurhan,GOKÇE HASAN Prognostic significance of poorly differentiated cluster grading system in intestinal type gastric adenocarcinoma. , 2020, ss.2022 - 2030. 10.5455/annalsmedres.2020.06.578
AMA GÜRÜNLÜOĞLU S,Samdanci E,ARSLAN A,AKPOLAT N,Sahin N,GOKÇE H Prognostic significance of poorly differentiated cluster grading system in intestinal type gastric adenocarcinoma. . 2020; 2022 - 2030. 10.5455/annalsmedres.2020.06.578
Vancouver GÜRÜNLÜOĞLU S,Samdanci E,ARSLAN A,AKPOLAT N,Sahin N,GOKÇE H Prognostic significance of poorly differentiated cluster grading system in intestinal type gastric adenocarcinoma. . 2020; 2022 - 2030. 10.5455/annalsmedres.2020.06.578
IEEE GÜRÜNLÜOĞLU S,Samdanci E,ARSLAN A,AKPOLAT N,Sahin N,GOKÇE H "Prognostic significance of poorly differentiated cluster grading system in intestinal type gastric adenocarcinoma." , ss.2022 - 2030, 2020. 10.5455/annalsmedres.2020.06.578
ISNAD GÜRÜNLÜOĞLU, SEMRA vd. "Prognostic significance of poorly differentiated cluster grading system in intestinal type gastric adenocarcinoma". (2020), 2022-2030. https://doi.org/10.5455/annalsmedres.2020.06.578
APA GÜRÜNLÜOĞLU S, Samdanci E, ARSLAN A, AKPOLAT N, Sahin N, GOKÇE H (2020). Prognostic significance of poorly differentiated cluster grading system in intestinal type gastric adenocarcinoma. Annals of Medical Research, 27(8), 2022 - 2030. 10.5455/annalsmedres.2020.06.578
Chicago GÜRÜNLÜOĞLU SEMRA,Samdanci Emine,ARSLAN Ahmet Kadir,AKPOLAT NUSRET,Sahin Nurhan,GOKÇE HASAN Prognostic significance of poorly differentiated cluster grading system in intestinal type gastric adenocarcinoma. Annals of Medical Research 27, no.8 (2020): 2022 - 2030. 10.5455/annalsmedres.2020.06.578
MLA GÜRÜNLÜOĞLU SEMRA,Samdanci Emine,ARSLAN Ahmet Kadir,AKPOLAT NUSRET,Sahin Nurhan,GOKÇE HASAN Prognostic significance of poorly differentiated cluster grading system in intestinal type gastric adenocarcinoma. Annals of Medical Research, vol.27, no.8, 2020, ss.2022 - 2030. 10.5455/annalsmedres.2020.06.578
AMA GÜRÜNLÜOĞLU S,Samdanci E,ARSLAN A,AKPOLAT N,Sahin N,GOKÇE H Prognostic significance of poorly differentiated cluster grading system in intestinal type gastric adenocarcinoma. Annals of Medical Research. 2020; 27(8): 2022 - 2030. 10.5455/annalsmedres.2020.06.578
Vancouver GÜRÜNLÜOĞLU S,Samdanci E,ARSLAN A,AKPOLAT N,Sahin N,GOKÇE H Prognostic significance of poorly differentiated cluster grading system in intestinal type gastric adenocarcinoma. Annals of Medical Research. 2020; 27(8): 2022 - 2030. 10.5455/annalsmedres.2020.06.578
IEEE GÜRÜNLÜOĞLU S,Samdanci E,ARSLAN A,AKPOLAT N,Sahin N,GOKÇE H "Prognostic significance of poorly differentiated cluster grading system in intestinal type gastric adenocarcinoma." Annals of Medical Research, 27, ss.2022 - 2030, 2020. 10.5455/annalsmedres.2020.06.578
ISNAD GÜRÜNLÜOĞLU, SEMRA vd. "Prognostic significance of poorly differentiated cluster grading system in intestinal type gastric adenocarcinoma". Annals of Medical Research 27/8 (2020), 2022-2030. https://doi.org/10.5455/annalsmedres.2020.06.578
Sayfa Oluşturulma Tarihi
23-04-2024 15:47

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