DETERMINATION OF THE EFFECTIVE TIME OF DENTURE CLEANSER TABLETS ON THE REMOVAL OF CANDIDA ALBICANS ON DENTURE BASE RESINS

Yıl: 2019 Cilt: 22 Sayı: 3 Sayfa Aralığı: 325 - 335 Metin Dili: İngilizce DOI: 10.7126/cumudj.566223 İndeks Tarihi: 17-12-2020

DETERMINATION OF THE EFFECTIVE TIME OF DENTURE CLEANSER TABLETS ON THE REMOVAL OF CANDIDA ALBICANS ON DENTURE BASE RESINS

Öz:
Objective: The aim of this study was to determinate of the effective time ofdifferent denture cleanser tablets on the removal of Candida albicans on variousbase resins.Materials and Methods: Conventional heat cured resin, high impact resin,autopolymerized resin, and polyamide resin were used. 160 samples were preparedfor each resin type. The biofilm of C. albicans was formed on the resins and thenexposed to alkaline peroxide tablet and enzymatic tablets for 3, 5, 10, 20, 40, 80,160 and 200 minutes. Cell viability was assessed by MTT test. 3-way ANOVAwas used for statistical analysis.Results: The effect of resin type, tablet type and application time on cell viabilityof C. albicans were found to be significant (p<0.05). Cell death was at least 65%on the resins even at the minimum time. Furthermore, as the duration ofadministration of both tablets increased, cell viability in all resins tended todecrease. The administration of both tablets on all resins for 10 min resulted inapproximately 80% cell death. Additionally, the most significant antimicrobialactivities of the tablets were determined at 20th minutes. The alkaline peroxidetablet on all base resins for application periods of 3 to 200 minutes was generallymore effective than the enzymatic tablet.Conclusions: Alkaline peroxide and enzymatic cleanser tablets showedremarkable anticandidal activity for all resins. The patients with risk of C. albicansinfection should keep their prostheses in cleanser tablets for at least 20 minutes.Furthermore, the anticandidal effect tended to increase with prolonged exposuretime.
Anahtar Kelime:

Protez Kaide Rezinleri Üzerindeki Candida Albicans'ın Uzaklaştırılmasında Protez Temizleyici Tabletlerin Etkin Sürelerinin Belirlenmesi

Öz:
Amaç: Bu çalışmanın amacı, çeşitli protez kaide rezinleri üzerindeki Candida albicans'ın uzaklaştırılmasında farklı protez temizleyici tabletlerin etkin sürelerinin belirlenmesidir. Gereç ve Yöntemler: Çalışmada geleneksel ısıyla polimerize olan rezin, yüksek çarpma dayanıklı rezin, otopolimerize rezin ve poliamid rezin kullanıldı. Her rezin tipi için 160 numune hazırlandı. C. albicans'ın biyofilmi rezinler üzerinde oluşturuldu ve daha sonra 3-5-10-20-40-80-160-200 dakika boyunca alkalin peroksit tablet ve enzimatik tablete maruz bırakıldı. Hücre canlılığı MTT testi ile değerlendirildi. İstatistiksel analiz için 3 yönlü ANOVA kullanıldı. Bulgular: Rezin tipi, tablet tipi ve uygulama süresinin rezinler üzerindeki C. albicans'ın hücre canlılığı üzerine etkisi anlamlı bulundu (p<0,05). Minimum sürede bile rezinlerde en az %65 hücre ölümü meydana geldi. Bununla birlikte, her iki tabletin uygulama süresi arttıkça, tüm rezinlerdeki hücre canlılığı azalma eğilimi gösterdi. Rezinlerin her iki tablete de 10 dakika maruz bırakılması tüm rezinlerde yaklaşık %80 hücre ölümüne neden oldu. Bununla birlikte, tabletlerin en önemli antimikrobiyal aktiviteleri 20. dakika da görülmüştür. Alkalin peroksit tablet, tüm protez kaide rezinleri üzerinde 3 ila 200 dakikalık uygulama süreleri için genel olarak enzimatik tabletten daha etkili olmuştur. Sonuçlar: Alkalin peroksit ve enzimatik temizleyici tabletler, tüm rezinler için kayda değer bir antikandidal aktivite göstermiştir. C. albicans enfeksiyonu riski taşıyan hastalar protezlerini temizleyici tabletlerde en az 20 dakika tutmalıdır. Bununla birlikte, antikandidal etki tablet süresinin uzaması ile artma eğilimindedir. Anahtar Kelimeler: Protez kaideleri, protez temizleyicileri, kandida albicans, hücre canlılığı.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Bibliyografik
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APA hayran y (2019). DETERMINATION OF THE EFFECTIVE TIME OF DENTURE CLEANSER TABLETS ON THE REMOVAL OF CANDIDA ALBICANS ON DENTURE BASE RESINS. , 325 - 335. 10.7126/cumudj.566223
Chicago hayran yeliz DETERMINATION OF THE EFFECTIVE TIME OF DENTURE CLEANSER TABLETS ON THE REMOVAL OF CANDIDA ALBICANS ON DENTURE BASE RESINS. (2019): 325 - 335. 10.7126/cumudj.566223
MLA hayran yeliz DETERMINATION OF THE EFFECTIVE TIME OF DENTURE CLEANSER TABLETS ON THE REMOVAL OF CANDIDA ALBICANS ON DENTURE BASE RESINS. , 2019, ss.325 - 335. 10.7126/cumudj.566223
AMA hayran y DETERMINATION OF THE EFFECTIVE TIME OF DENTURE CLEANSER TABLETS ON THE REMOVAL OF CANDIDA ALBICANS ON DENTURE BASE RESINS. . 2019; 325 - 335. 10.7126/cumudj.566223
Vancouver hayran y DETERMINATION OF THE EFFECTIVE TIME OF DENTURE CLEANSER TABLETS ON THE REMOVAL OF CANDIDA ALBICANS ON DENTURE BASE RESINS. . 2019; 325 - 335. 10.7126/cumudj.566223
IEEE hayran y "DETERMINATION OF THE EFFECTIVE TIME OF DENTURE CLEANSER TABLETS ON THE REMOVAL OF CANDIDA ALBICANS ON DENTURE BASE RESINS." , ss.325 - 335, 2019. 10.7126/cumudj.566223
ISNAD hayran, yeliz. "DETERMINATION OF THE EFFECTIVE TIME OF DENTURE CLEANSER TABLETS ON THE REMOVAL OF CANDIDA ALBICANS ON DENTURE BASE RESINS". (2019), 325-335. https://doi.org/10.7126/cumudj.566223
APA hayran y (2019). DETERMINATION OF THE EFFECTIVE TIME OF DENTURE CLEANSER TABLETS ON THE REMOVAL OF CANDIDA ALBICANS ON DENTURE BASE RESINS. Cumhuriyet Dental Journal , 22(3), 325 - 335. 10.7126/cumudj.566223
Chicago hayran yeliz DETERMINATION OF THE EFFECTIVE TIME OF DENTURE CLEANSER TABLETS ON THE REMOVAL OF CANDIDA ALBICANS ON DENTURE BASE RESINS. Cumhuriyet Dental Journal 22, no.3 (2019): 325 - 335. 10.7126/cumudj.566223
MLA hayran yeliz DETERMINATION OF THE EFFECTIVE TIME OF DENTURE CLEANSER TABLETS ON THE REMOVAL OF CANDIDA ALBICANS ON DENTURE BASE RESINS. Cumhuriyet Dental Journal , vol.22, no.3, 2019, ss.325 - 335. 10.7126/cumudj.566223
AMA hayran y DETERMINATION OF THE EFFECTIVE TIME OF DENTURE CLEANSER TABLETS ON THE REMOVAL OF CANDIDA ALBICANS ON DENTURE BASE RESINS. Cumhuriyet Dental Journal . 2019; 22(3): 325 - 335. 10.7126/cumudj.566223
Vancouver hayran y DETERMINATION OF THE EFFECTIVE TIME OF DENTURE CLEANSER TABLETS ON THE REMOVAL OF CANDIDA ALBICANS ON DENTURE BASE RESINS. Cumhuriyet Dental Journal . 2019; 22(3): 325 - 335. 10.7126/cumudj.566223
IEEE hayran y "DETERMINATION OF THE EFFECTIVE TIME OF DENTURE CLEANSER TABLETS ON THE REMOVAL OF CANDIDA ALBICANS ON DENTURE BASE RESINS." Cumhuriyet Dental Journal , 22, ss.325 - 335, 2019. 10.7126/cumudj.566223
ISNAD hayran, yeliz. "DETERMINATION OF THE EFFECTIVE TIME OF DENTURE CLEANSER TABLETS ON THE REMOVAL OF CANDIDA ALBICANS ON DENTURE BASE RESINS". Cumhuriyet Dental Journal 22/3 (2019), 325-335. https://doi.org/10.7126/cumudj.566223